La Plata to Veinticinco de Agosto, Uruguay

By admin, 13 October, 2026

By road, La Plata and Veinticinco de Agosto, Uruguay are about 361 miles (581 km) apart, or roughly 7 h 33 min of driving. You cross from Argentina into Uruguay at about mile 201, at the Gualeguaychú–Fray Bentos bridge.

U.S. State Department travel advisory: Argentina — Level 1, Exercise Normal Precautions; Uruguay — Level 2, Exercise Increased Caution

Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
  • Uruguay: “Traffic fatalities are high in Uruguay.”
Museo de la Pasión BoquenseMuseo de la Casa RosadaSan José ObservatorySt. George Antiochian Orthodox Cathedral, Buenos AiresMuseo Nacional del HombreMuseo PueyrredonGualeguaychú CathedralFrigorífico Anglo del UruguayCathedral of San José de MayoArgentina–Uruguay borderLa PlataVeinticinco de Agosto
Route from La Plata to Veinticinco de Agosto with the 9 stops listed below (blue dots) and the approximate Argentina–Uruguay border crossing (red square).
Distance361 mi (581 km)
Time at the wheel, no stops7 h 33 min
Main roads, in orderRN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN136
Border crossingabout mile 201, Argentina → Uruguay (the Gualeguaychú–Fray Bentos bridge)
Regions on the routeBuenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Florida
Fuel estimate (car at 25 mpg)about 14.5 gal; actual use varies by vehicle and traffic
Stops listed below9

Getting across the Argentina–Uruguay border

The route crosses at about mile 201, at the Gualeguaychú–Fray Bentos bridge, from Entre Ríos into Río Negro. Plan on two checks on each side: immigration for your passport and customs for the car.

Entering Uruguay (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date.
Driving in UruguayYou can drive on your U.S. license.
Entering Argentina (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps.
Driving in ArgentinaA valid U.S. license usually works; an International Driving Permit is recommended.
Rental carCross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book.

Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.

The La Plata–Veinticinco de Agosto drive in a few lines

RN12 (47 mi) and RN9 (39 mi) carry about 24% of the 361 miles. The first 201 miles are in Argentina; the last 160 are in Uruguay. It runs through 8 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Florida. Of the 9 stops listed below, 3 are within a mile of the road.

Road-by-road breakdown: La Plata to Veinticinco de Agosto

RoadRoute miles (from–to)Length, miRegion
local roads0–33Buenos Aires
RN13–3330Buenos Aires, Ciudad de Buenos Aires
local roads33–374Ciudad de Buenos Aires
AV1-N37–425Ciudad de Buenos Aires
connecting roads42–453Ciudad de Buenos Aires
RN945–8439Buenos Aires
connecting roads84–851Buenos Aires
RP685–894Buenos Aires
RN1289–13647Buenos Aires, Entre Ríos
RN14136–17337Entre Ríos
local roads173–1796Entre Ríos
RN136179–19819Entre Ríos
connecting roads198–2013Entre Ríos
local roads201–29897Río Negro, Soriano
connecting roads298–2991Soriano
local roads299–33536Colonia, San José
connecting roads335–3383San José
local roads338–36123San José
  • Mile 29 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
  • Mile 45 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
  • Mile 107 of this route: Buenos Aires → Entre Ríos (region line)
  • Mile 201 of this route: Entre Ríos → Río Negro (international border)
  • Mile 217 of this route: Río Negro → Soriano (region line)
  • Mile 299 of this route: Soriano → Colonia (region line)
  • Mile 316 of this route: Colonia → San José (region line)
  • Mile 361 of this route: San José → Florida (region line)

Stops between La Plata and Veinticinco de Agosto

  • Right off the route (under 1 mile): Museo de la Pasión Boquense (mile 32), Museo de la Casa Rosada (mile 35), Cathedral of San José de Mayo (mile 336)
  • Museums and history: Museo de la Pasión Boquense (mile 32), Museo de la Casa Rosada (mile 35), St. George Antiochian Orthodox Cathedral, Buenos Aires (mile 39), Museo Nacional del Hombre (mile 40), Museo Pueyrredon (mile 48), Gualeguaychú Cathedral (mile 178), Cathedral of San José de Mayo (mile 336)

Museo de la Pasión Boquense

Mile 32 · Sports museum · 0.6 mi from the route

Football fans can dig into the history and personalities of Club Atlético Boca Juniors at the Museo de la Pasión Boquense, a themed soccer museum devoted to the club.

Museo de la Casa Rosada

Mile 35 · Museum · 0.2 mi from the route

Set in the old galleries of the Taylor Customs House in Buenos Aires, this museum opened in 2011 and displays about 10,000 historic pieces that belonged to Argentine presidents.

San José Observatory

Mile 36 · Observatory · 2 mi from the route

The San José Observatory is an amateur astronomy observatory in Buenos Aires, founded in 1913 in a structure first built in 1870.

St. George Antiochian Orthodox Cathedral, Buenos Aires

Mile 39 · Cathedral · 2 mi from the route · side trip; actual detour depends on access roads

St. George Antiochian Orthodox Cathedral serves as the cathedral of the Archdiocese of Buenos Aires and All Argentina under the Greek Orthodox Patriarchate of Antioch.

Museo Nacional del Hombre

Mile 40 · Museum · 1 mi from the route

In the Belgrano district of Buenos Aires, the Museo Nacional del Hombre is a national museum focused on the archaeology of South America's Indigenous peoples.

Museo Pueyrredon

Mile 48 · Art museum · 3 mi from the route · side trip; actual detour depends on access roads

In Acassuso, in the San Isidro district of Buenos Aires Province, this municipal history museum bears the name of Brigadier General Juan Martín de Pueyrredón.

Gualeguaychú Cathedral

Mile 178 · Cathedral · 1 mi from the route

St. Joseph's Cathedral, also called Gualeguaychú Cathedral, is the mother church of the Roman Catholic Diocese of Gualeguaychú in Argentina.

Frigorífico Anglo del Uruguay

Mile 201 · Industrial heritage site · 5 mi from the route · side trip; actual detour depends on access roads

The former Anglo meatpacking plant on the Uruguay River at Fray Bentos began shipping frozen meat in 1924, on the site where Liebig exported meat extract and corned beef from 1865. It is part of a UNESCO World Heritage landscape inscribed in 2015.

Cathedral of San José de Mayo

Mile 336 · Cathedral · 0.9 mi from the route

The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.

More drives to Veinticinco de Agosto

More drives from La Plata

Frequently asked questions

How long does it take to drive from La Plata to Veinticinco de Agosto, Uruguay?

About 7 h 33 min of driving without stops, over 361 miles.

What is the driving distance from La Plata to Veinticinco de Agosto, Uruguay?

About 361 miles (581 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Where does the La Plata to Veinticinco de Agosto drive cross the border?

At about mile 201, from Argentina into Uruguay, at the Gualeguaychú–Fray Bentos bridge.

What do U.S. citizens need to drive from La Plata into Uruguay?

No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)

Is it safe to drive from La Plata to Veinticinco de Agosto, Uruguay?

The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from La Plata to Veinticinco de Agosto use?

In order: RN1, AV1-N, RN9, RP6, RN12, RN14 and RN136. The road-by-road table above shows the route miles for each one.

What are good stops between La Plata and Veinticinco de Agosto?

Closest to the road: Museo de la Pasión Boquense (sports museum, mile 32, 0.6 mi from the route); Museo de la Casa Rosada (museum, mile 35, 0.2 mi from the route); Cathedral of San José de Mayo (cathedral, mile 336, 0.9 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.