The Wayro route from Itapetininga to Barretos is 254 miles (409 km), about 5 h 4 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Distance by road | 254 mi (409 km) |
|---|---|
| Driving time, no stops | 5 h 4 min |
| Main roads, in order | SP-270 → SP-127 → BR-373 → SP-310 → SP-326 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 10.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
How the Itapetininga to Barretos drive plays out
SP-127 (86 mi) and SP-326 (80 mi) carry about 65% of the 254 miles. Of the 8 stops listed below, 1 are within a mile of the road.
Itapetininga to Barretos: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SP-270 | 1–6 | 5 | São Paulo |
| SP-127 | 6–73 | 67 | São Paulo |
| BR-373 | 73–76 | 3 | São Paulo |
| connecting roads | 76–78 | 2 | São Paulo |
| SP-127 | 78–97 | 19 | São Paulo |
| connecting roads | 97–98 | 1 | São Paulo |
| SP-310 | 98–172 | 74 | São Paulo |
| SP-326 | 172–252 | 80 | São Paulo |
| local roads | 252–254 | 2 | São Paulo |
Places worth a stop between Itapetininga and Barretos
- Right off the route (under 1 mile): Museu Histórico e Pedagógico Prudente de Moraes (mile 76)
- Museums and history: Museu Paulo Setúbal (mile 27), Museu Histórico e Pedagógico Prudente de Moraes (mile 76), Museu de Minerais e Rochas Heinz Ebert (mile 99), St. Charles Borromeo Cathedral, São Carlos (mile 135), Museu Histórico e Pedagógico Cerqueira César (mile 135), Casa da Cultura Luís Antonio Martinez Corrêa (mile 160), Our Lady of Carmel Cathedral, Jaboticabal (mile 202), André Matarazzo Museum of Arms, Vehicles and Machines Eduardo (mile 225)
Museu Paulo Setúbal
Housed in Tatuí's former jail and courthouse, finished in 1920, the Paulo Setúbal Historical Museum (Museu Histórico Paulo Setúbal) honors the local-born novelist with rooms on his life, town history and Tatuí soldiers of World War II.
Museu Histórico e Pedagógico Prudente de Moraes
Piracicaba's Prudente de Moraes museum fills the 19th-century home where Brazil's first civilian president lived until his death in 1902, with his belongings, local art and an exhibit on the city's history.
Museu de Minerais e Rochas Heinz Ebert
In Rio Claro, Unesp's Institute of Geosciences and Exact Sciences houses the Museu de Minerais e Rochas Heinz Ebert in its Department of Petrology and Metallogeny building.
St. Charles Borromeo Cathedral, São Carlos
St. Charles Borromeo Cathedral is a Catholic church on Dom José Marcondes Homem de Melo Square in the city of São Carlos, São Paulo state.
Museu Histórico e Pedagógico Cerqueira César
Now called Museu de São Carlos, this museum opened in 1957 and holds over 7,000 items about the city, including a replica of a carriage like Dom Pedro II's from his 1886 visit.
Casa da Cultura Luís Antonio Martinez Corrêa
Araraquara's Casa da Cultura occupies a 1914 mansion protected by São Paulo's heritage council, CONDEPHAAT. It holds historical collections ranging from documents to artworks, plus a small theater and rooms for cultural workshops.
Our Lady of Carmel Cathedral, Jaboticabal
Jaboticabal's Our Lady of Carmel Cathedral stands on Joaquim Batista Square, the city's zero point. It serves as seat of the Catholic Diocese of Jaboticabal and became a parish in 1898.
André Matarazzo Museum of Arms, Vehicles and Machines Eduardo
Known locally as the Museu do Automóvel, Bebedouro's private museum grew from Eduardo André Matarazzo's collection of vintage vehicles and also shows retired airliners outdoors, including a DC-3 and a Vickers Viscount.
Arriving in Barretos
Museu Ruy Menezes
In Barretos, São Paulo, the Ruy Menezes Historical, Artistic and Folkloric Museum safeguards the city's memory through documents and objects from local history.
More drives to Barretos
- Araraquara to Barretos
- São Carlos to Barretos
- Limeira to Barretos
- Piracicaba to Barretos
- Poços de Caldas to Barretos
- Campinas to Barretos
From Itapetininga to other places in Brazil
- Itapetininga to Paranapiacaba
- Itapetininga to Cubatão
- Itapetininga to Mogi Guaçu
- Itapetininga to Itanhaém
- Itapetininga to Araxá
- Itapetininga to Araguari
Frequently asked questions
How long does it take to drive from Itapetininga to Barretos?
About 5 h 4 min of driving without stops, over 254 miles.
How far is Barretos from Itapetininga by car?
About 254 miles (409 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Itapetininga to Barretos drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Itapetininga to Barretos use?
In order: SP-270, SP-127, BR-373, SP-310 and SP-326. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Itapetininga to Barretos?
Closest to the road: Museu Paulo Setúbal (museum, mile 27, 1 mi from the route); Museu Histórico e Pedagógico Prudente de Moraes (museum, mile 76, 0.2 mi from the route); Casa da Cultura Luís Antonio Martinez Corrêa (historic site, mile 160, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.