Plan on about 11 h 30 min of driving for the 544-mile (876 km) trip from Itajaí to Resende, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Flooding makes some roads through the Amazon impassable for much of the year.”
| Distance | 544 mi (876 km) |
|---|---|
| Driving time, no stops | 11 h 30 min |
| Main roads, in order | BR-101 → BR-376 → BR-116 → SP-021 → SP-015 → SP-060 |
| States on the route | Santa Catarina, Paraná, São Paulo, Rio de Janeiro |
| Fuel estimate (car at 25 mpg) | about 21.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
What the drive from Itajaí to Resende is like
BR-116 (236 mi) and SP-060 (160 mi) carry about 73% of the 544 miles. It runs through 4 states: Santa Catarina, Paraná, São Paulo, Rio de Janeiro. Of the 9 stops listed below, 4 are within a mile of the road.
Roads you'll take from Itajaí to Resende
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | Santa Catarina |
| BR-101 | 4–78 | 74 | Santa Catarina |
| BR-376 | 78–121 | 43 | Santa Catarina, Paraná |
| BR-116 | 121–357 | 236 | Paraná, São Paulo |
| connecting roads | 357–358 | 1 | São Paulo |
| SP-021 | 358–366 | 8 | São Paulo |
| connecting roads | 366–372 | 6 | São Paulo |
| SP-015 | 372–382 | 10 | São Paulo |
| SP-060 | 382–542 | 160 | São Paulo, Rio de Janeiro |
| local roads | 542–544 | 2 | Rio de Janeiro |
- Mile 79 of this route: Santa Catarina → Paraná (state line)
- Mile 185 of this route: Paraná → São Paulo (state line)
- Mile 526 of this route: São Paulo → Rio de Janeiro (state line)
What to see on the way from Itajaí to Resende
- Right off the route (under 1 mile): Museu do Índio (mile 356), Desinfectório Central (mile 378), Basilica of Our Lady of Aparecida (mile 482), Itatiaia National Park (mile 535)
- Nature and outdoors: Guaricana National Park (mile 90), Roberto Ribas Lange State Park (mile 149), Rio Turvo State Park (mile 212), Campina do Encantado State Park (mile 249), Itatiaia National Park (mile 535)
- Museums and history: Museu Nacional de Imigração e Colonização (mile 52), Museu do Índio (mile 356), Desinfectório Central (mile 378), Basilica of Our Lady of Aparecida (mile 482)
Museu Nacional de Imigração e Colonização
Joinville's Museu Nacional de Imigração e Colonização keeps memories, stories and objects tied to immigration in southern Brazil; it was created by federal law in 1957.
Guaricana National Park
Created in 2014, Guaricana National Park protects about 49,300 hectares of the Serra do Mar in Paraná, across Guaratuba, Morretes and São José dos Pinhais, within the largest continuous stretch of dense Atlantic Forest in Brazil.
Roberto Ribas Lange State Park
Created in 1994 near Antonina and Morretes on the Paraná coast, Roberto Ribas Lange State Park protects Atlantic Forest on the steep slopes of the Serra do Mar. Hundreds of bird species have been recorded in its dense rainforest.
Rio Turvo State Park
Spanning about 73,900 hectares of Atlantic Forest in Cajati, Barra do Turvo and Jacupiranga, Rio Turvo State Park has trails, the Cachoeira do Azeite waterfall, Morro do Guaraú and the Gruta da Capelinha cave.
Campina do Encantado State Park
Campina do Encantado State Park, in the São Paulo state town of Pariquera-Açu, protects a peat bog and a patch of wetland forest, described as a unique ecosystem of great scientific interest.
Museu do Índio
In Embu das Artes, São Paulo, this private museum linked to an Indigenous culture information center displays over 500 ethnographic pieces and runs cultural programs about Brazil's Indigenous peoples.
Desinfectório Central
Built in 1893 by the São Paulo state government to fight epidemics through disinfection, the Desinfectório Central was listed as heritage in 1985 and now houses the Emílio Ribas Museum of Public Health.
Basilica of Our Lady of Aparecida
Brazil's National Shrine in Aparecida houses the image of Our Lady Aparecida that fishermen pulled from the Paraíba do Sul River in 1717. Work on the current basilica began in 1955, and Pope John Paul II consecrated it in 1980.
Itatiaia National Park
Brazil's national park system started here: Itatiaia National Park (Parque Nacional do Itatiaia) was created in 1937 as the country's first. The protected area lies on the border between Rio de Janeiro and Minas Gerais states.
More drives to Resende
- Niterói to Resende
- São José dos Campos to Resende
- Jacareí to Resende
- Mogi das Cruzes to Resende
- São Paulo to Resende
- Jundiaí to Resende
From Itajaí to other places in Brazil
- Itajaí to Paranaguá
- Itajaí to Guarapuava
- Itajaí to Passo Fundo
- Itajaí to São Leopoldo
- Itajaí to Itanhaém
- Itajaí to Novo Hamburgo
Frequently asked questions
How long does it take to drive from Itajaí to Resende?
About 11 h 30 min of driving without stops, over 544 miles.
How far is Resende from Itajaí by car?
About 544 miles (876 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Itajaí to Resende drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Itajaí to Resende use?
In order: BR-101, BR-376, BR-116, SP-021, SP-015 and SP-060. The road-by-road table above shows the route miles for each one.
What are good stops between Itajaí and Resende?
Closest to the road: Museu do Índio (museum, mile 356, 0.4 mi from the route); Basilica of Our Lady of Aparecida (basilica, mile 482, 0.4 mi from the route); Itatiaia National Park (national park, mile 535, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.