Itajaí to Botucatu is about 452 road miles (727 km): roughly 9 h 21 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Road maintenance is inadequate in many areas.”
| Total distance | 452 mi (727 km) |
|---|---|
| Time at the wheel, no stops | 9 h 21 min |
| Main roads, in order | BR-101 → BR-376 → BR-116 → BR-277 → PRC-373 → PR-151 → PR-239 → SP-281 → SP-255 → SP-280 → SP-209 |
| States on the route | Santa Catarina, Paraná, São Paulo |
| Fuel estimate (car at 25 mpg) | about 18.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
The Itajaí–Botucatu drive in a few lines
PR-151 (89 mi) and BR-101 (74 mi) carry about 36% of the 452 miles. It runs through 3 states: Santa Catarina, Paraná, São Paulo. Of the 9 stops listed below, 3 are within a mile of the road.
Itajaí to Botucatu: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | Santa Catarina |
| BR-101 | 4–78 | 74 | Santa Catarina |
| BR-376 | 78–121 | 43 | Santa Catarina, Paraná |
| BR-116 | 121–129 | 8 | Paraná |
| BR-277 | 129–198 | 69 | Paraná |
| BR-376 | 198–205 | 7 | Paraná |
| PRC-373 | 205–210 | 5 | Paraná |
| PR-151 | 210–299 | 89 | Paraná |
| PR-239 | 299–307 | 8 | Paraná |
| connecting roads | 307–309 | 2 | Paraná, São Paulo |
| SP-281 | 309–344 | 35 | São Paulo |
| SP-255 | 344–417 | 73 | São Paulo |
| connecting roads | 417–418 | 1 | São Paulo |
| SP-280 | 418–437 | 19 | São Paulo |
| SP-209 | 437–450 | 13 | São Paulo |
| local roads | 450–452 | 2 | São Paulo |
- Mile 79 of this route: Santa Catarina → Paraná (state line)
- Mile 308 of this route: Paraná → São Paulo (state line)
Places worth a stop between Itajaí and Botucatu
- Right off the route (under 1 mile): Antigo Engenho de Mate da Rondinha (mile 145), Vila Velha State Park (mile 189), Jaguariaíva River Canyon (mile 283)
- Nature and outdoors: Vila Velha State Park (mile 189), Campos Gerais National Park (mile 213), Jaguariaíva River Canyon (mile 283)
- Museums and history: Museu Casa Fritz Alt (mile 52), Museu Arqueológico de Sambaqui de Joinville (mile 53), Antigo Engenho de Mate da Rondinha (mile 145), Museu de Arqueologia de Ponta Grossa (mile 201), Casa da Memória Paraná (mile 206)
Museu Casa Fritz Alt
Artist Fritz Alt's 1940s home in Joinville opened as a museum in 1975; its setting on Morro do Boa Vista gives visitors a panoramic view of the city.
Museu Arqueológico de Sambaqui de Joinville
In Joinville, Santa Catarina, this archaeological museum explores the way of life and culture of the fisher-hunter-gatherer groups who were among the first peoples to spread across South America and settle what is now Brazil.
Antigo Engenho de Mate da Rondinha
In Campo Largo, Paraná, the Parque Histórico do Mate is a themed park that tells the story of the yerba mate cycle and ranks among the town's visitor attractions.
Vila Velha State Park
Also called the Old Village State Park, Vila Velha State Park covers 9,397 acres in the municipality of Ponta Grossa, Paraná.
Museu de Arqueologia de Ponta Grossa
Officially the Museu de Arqueologia Ciro Flamarion Cardoso, this Ponta Grossa museum opened in 2001 and holds objects on the history, art and archaeology of ancient Egypt.
Casa da Memória Paraná
In Ponta Grossa, Paraná, Casa da Memória Paraná is a museum and memorial that documents the history of the city, the Campos Gerais region and the state.
Campos Gerais National Park
Created in 2006 across Ponta Grossa, Castro and Carambeí, Campos Gerais National Park protects native grasslands and Araucaria forest, with visitor sites like the Buraco do Padre sinkhole and the Mariquinha and São Jorge River waterfalls.
Jaguariaíva River Canyon
The Jaguariaíva River runs through this canyon in Jaguariaíva, in the Brazilian state of Paraná.
Abadia de Santa Cruz
Founded in 1936 by German monks from Himmerod Abbey, the Abadia de Santa Cruz is a Cistercian monastery in Itaporanga, São Paulo state.
More drives to Botucatu
- Franca to Botucatu
- Uberlândia to Botucatu
- Rio Verde to Botucatu
- Campinas to Botucatu
- Bragança Paulista to Botucatu
- Jundiaí to Botucatu
From Itajaí to other places in Brazil
- Itajaí to Paranaguá
- Itajaí to Guarapuava
- Itajaí to Passo Fundo
- Itajaí to São Leopoldo
- Itajaí to Itanhaém
- Itajaí to Novo Hamburgo
Frequently asked questions
How long does it take to drive from Itajaí to Botucatu?
About 9 h 21 min of driving without stops, over 452 miles.
How far is Botucatu from Itajaí by car?
About 452 miles (727 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Itajaí to Botucatu drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Itajaí to Botucatu use?
In order: BR-101, BR-376, BR-116, BR-277, PRC-373, PR-151, PR-239, SP-281, SP-255, SP-280 and SP-209. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Itajaí to Botucatu?
Closest to the road: Antigo Engenho de Mate da Rondinha (museum, mile 145, 0.3 mi from the route); Vila Velha State Park (state park, mile 189, 0.9 mi from the route); Jaguariaíva River Canyon (canyon, mile 283, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.