Plan on about 4 h 10 min of driving for the 204-mile (329 km) trip from Guarujá to São Carlos, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Flooding makes some roads through the Amazon impassable for much of the year.”
| Distance by road | 204 mi (329 km) |
|---|---|
| Drive time without stops | 4 h 10 min |
| Main roads, in order | SPA-248/055 → SP-160 → SP-015 → SP-348 → SPA-102/330 → SP-330 → SP-310 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 8.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
How the Guarujá to São Carlos drive plays out
SP-348 (49 mi) and SP-310 (47 mi) carry about 47% of the 204 miles. None of the 9 stops below is right on the road, so plan each as a short side trip.
The route from Guarujá to São Carlos, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SPA-248/055 | 1–19 | 18 | São Paulo |
| connecting roads | 19–22 | 3 | São Paulo |
| SP-160 | 22–53 | 31 | São Paulo |
| local roads | 53–58 | 5 | São Paulo |
| SP-015 | 58–66 | 8 | São Paulo |
| connecting roads | 66–68 | 2 | São Paulo |
| SP-348 | 68–117 | 49 | São Paulo |
| SPA-102/330 | 117–122 | 5 | São Paulo |
| SP-330 | 122–153 | 31 | São Paulo |
| connecting roads | 153–154 | 1 | São Paulo |
| SP-310 | 154–201 | 47 | São Paulo |
| local roads | 201–204 | 3 | São Paulo |
Breaking up the drive: stops between Guarujá and São Carlos
- Museums and history: Pelé Museum (mile 7), Museu Lasar Segall (mile 55), Luiz Cássio dos Santos Werneck Memorial (mile 58), Fundadores de São Paulo (mile 59), Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão (mile 138), Museu de Minerais e Rochas Heinz Ebert (mile 168)
- With kids: São Paulo Aquarium (mile 53)
Pelé Museum
Pelé Museum (Museu Pelé) in Santos is dedicated to the career of former player Pelé. It opened in June 2014 as part of the side events of the FIFA World Cup.
São Paulo Aquarium
The São Paulo Aquarium is an oceanarium in the Ipiranga district of São Paulo, opened in July 2006 as the first themed aquarium in Latin America.
Museu Lasar Segall
Housed in the home and studio architect Gregori Warchavchik designed in 1932, the Museu Lasar Segall in São Paulo is an art museum devoted to artist Lasar Segall, who lived there until 1957.
Luiz Cássio dos Santos Werneck Memorial
Opened in 1994, the Luiz Cássio dos Santos Werneck Memorial preserves the history of São Paulo Futebol Clube, displaying historic objects to fans and visitors.
Fundadores de São Paulo
In São Paulo's Vila Mariana neighborhood, Fundadores de São Paulo is a monument by sculptor Luis Morrone honoring the city's founders, inaugurated in 1963 after ten years of construction.
Teatro J. Safra
Teatro J. Safra is a theater in the city of São Paulo, with Maurício Machado serving as its manager and artistic curator.
Teatro Polytheama
Opened in 1911, Teatro Polytheama is a performance venue in Jundiaí, in the interior of São Paulo state.
Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão
Americana's municipal history museum occupies the old headquarters of the Fazenda Salto Grande, near where the Atibaia and Jaguari rivers meet to form the Piracicaba, and is run by the city's culture and tourism department.
Museu de Minerais e Rochas Heinz Ebert
On the Unesp university campus in Rio Claro, the Museu de Minerais e Rochas Heinz Ebert occupies the building of the Department of Petrology and Metallogeny at the Institute of Geosciences and Exact Sciences.
In São Carlos itself
Museu Histórico e Pedagógico Cerqueira César
Now called Museu de São Carlos, this museum opened in 1957 and holds over 7,000 items about the city, including a replica of a carriage like Dom Pedro II's from his 1886 visit.
St. Charles Borromeo Cathedral, São Carlos
St. Charles Borromeo Cathedral is a Catholic church on Dom José Marcondes Homem de Melo Square in the city of São Carlos, São Paulo state.
São Carlos Municipal Theatre
Officially named Teatro Municipal Dr. Alderico Vieira Perdigão, the São Carlos Municipal Theatre is the city's public theater in São Carlos, in the interior of São Paulo state.
More drives to São Carlos
- Jundiaí to São Carlos
- São Paulo to São Carlos
- São Vicente to São Carlos
- Santos to São Carlos
- Mogi das Cruzes to São Carlos
- Taubaté to São Carlos
From Guarujá to other places in Brazil
- Guarujá to Paranapiacaba
- Guarujá to Bragança Paulista
- Guarujá to Itu
- Guarujá to Limeira
- Guarujá to Mogi Guaçu
- Guarujá to Botucatu
Frequently asked questions
How long is the drive from Guarujá to São Carlos?
About 4 h 10 min of driving without stops, over 204 miles.
How far is São Carlos from Guarujá by car?
About 204 miles (329 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Guarujá to São Carlos?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Guarujá to São Carlos?
In order: SPA-248/055, SP-160, SP-015, SP-348, SPA-102/330, SP-330 and SP-310. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Guarujá to São Carlos?
Closest to the road: Luiz Cássio dos Santos Werneck Memorial (sports museum, mile 58, 2 mi from the route); Fundadores de São Paulo (monument, mile 59, 2 mi from the route); Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão (museum, mile 138, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.