Plan on about 10 h 20 min of driving for the 508-mile (818 km) trip from Guarujá to Patos de Minas, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Use caution when walking or driving at night.”
| Distance by road | 508 mi (818 km) |
|---|---|
| Drive time without stops | 10 h 20 min |
| Main roads, in order | SPA-248/055 → SP-160 → SP-015 → SP-348 → SPA-102/330 → SP-330 → SP-334 → MG-428 → BR-146 → BR-365 |
| States on the route | São Paulo, Minas Gerais |
| Fuel estimate (car at 25 mpg) | about 20.3 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
The Guarujá–Patos de Minas drive in a few lines
SP-330 (134 mi) and SP-334 (91 mi) carry about 44% of the 508 miles. It runs through 2 states: São Paulo, Minas Gerais. Of the 8 stops listed below, 4 are within a mile of the road.
Guarujá to Patos de Minas: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | São Paulo |
| SPA-248/055 | 1–19 | 18 | São Paulo |
| connecting roads | 19–22 | 3 | São Paulo |
| SP-160 | 22–53 | 31 | São Paulo |
| local roads | 53–58 | 5 | São Paulo |
| SP-015 | 58–66 | 8 | São Paulo |
| connecting roads | 66–68 | 2 | São Paulo |
| SP-348 | 68–117 | 49 | São Paulo |
| SPA-102/330 | 117–122 | 5 | São Paulo |
| SP-330 | 122–256 | 134 | São Paulo |
| connecting roads | 256–257 | 1 | São Paulo |
| SP-334 | 257–348 | 91 | São Paulo |
| MG-428 | 348–407 | 59 | São Paulo, Minas Gerais |
| connecting roads | 407–409 | 2 | Minas Gerais |
| BR-146 | 409–488 | 79 | Minas Gerais |
| BR-365 | 488–503 | 15 | Minas Gerais |
| local roads | 503–508 | 5 | Minas Gerais |
- Mile 349 of this route: São Paulo → Minas Gerais (state line)
Places worth a stop between Guarujá and Patos de Minas
- Right off the route (under 1 mile): Museu de Ciências da Universidade de São Paulo (mile 52), Basílica Nossa Senhora do Patrocínio (mile 163), Vassununga State Park (mile 211), Museu Casa de Portinari (mile 268)
- Nature and outdoors: Vassununga State Park (mile 211), Furnas do Bom Jesus State Park (mile 334)
- Museums and history: Museu de Ciências da Universidade de São Paulo (mile 52), Museu Lasar Segall (mile 55), Xingu Museum (mile 60), Basílica Nossa Senhora do Patrocínio (mile 163), Museu Casa de Portinari (mile 268)
Museu de Ciências da Universidade de São Paulo
The University of São Paulo's Science Museum, created in 2005, brings the exact, human and natural sciences, technology and the arts to the public beyond the campus.
Museu Lasar Segall
Housed in the home and studio architect Gregori Warchavchik designed in 1932, the Museu Lasar Segall in São Paulo is an art museum devoted to artist Lasar Segall, who lived there until 1957.
Teatro Procópio Ferreira
Teatro Procópio Ferreira is a theater in São Paulo, Brazil, where audiences can catch live stage shows.
Xingu Museum
Created in 2012, the private Xingu Museum (Museu Xingu) in São Paulo displays Indigenous artifacts once owned by anthropologist Orlando Villas Bôas, made from feathers, clay, wood and fiber.
Basílica Nossa Senhora do Patrocínio
Araras' Basílica Nossa Senhora do Patrocínio is a Catholic parish church that Pope Benedict XVI elevated to the rank of minor basilica in 2010; it belongs to the Diocese of Limeira.
Vassununga State Park
Vassununga State Park, beside the Anhanguera highway in Santa Rita do Passa Quatro, protects Atlantic Forest and cerrado and shelters the Patriarca, a jequitibá-rosa about 42 meters tall estimated at roughly 600 years old.
Museu Casa de Portinari
In Brodowski, Candido Portinari's childhood home is now the Museu Casa de Portinari, where the painter often returned to stay with family. Inside are several of his works, mostly murals painted in fresco and tempera.
Furnas do Bom Jesus State Park
Furnas do Bom Jesus State Park in São Paulo state protects cerrado and Atlantic Forest with high biodiversity in and around a canyon.
Once you reach Patos de Minas
St. Anthony of Padua Cathedral, Patos de Minas
St. Anthony of Padua Cathedral, also called Patos de Minas Cathedral, is a Catholic church in the city of Patos de Minas, Minas Gerais.
More drives to Patos de Minas
- Ipatinga to Patos de Minas
- Marília to Patos de Minas
- Bragança Paulista to Patos de Minas
- Sorocaba to Patos de Minas
- São Paulo to Patos de Minas
- Teresópolis to Patos de Minas
From Guarujá to other places in Brazil
- Guarujá to Paranapiacaba
- Guarujá to Bragança Paulista
- Guarujá to Itu
- Guarujá to Limeira
- Guarujá to Mogi Guaçu
- Guarujá to Botucatu
Frequently asked questions
How long does it take to drive from Guarujá to Patos de Minas?
About 10 h 20 min of driving without stops, over 508 miles.
How far is Patos de Minas from Guarujá by car?
About 508 miles (818 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Guarujá to Patos de Minas drive?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Guarujá to Patos de Minas use?
In order: SPA-248/055, SP-160, SP-015, SP-348, SPA-102/330, SP-330, SP-334, MG-428, BR-146 and BR-365. The road-by-road table above shows the route miles for each one.
What are good stops between Guarujá and Patos de Minas?
Closest to the road: Museu de Ciências da Universidade de São Paulo (museum, mile 52, 0.6 mi from the route); Vassununga State Park (state park, mile 211, 0.4 mi from the route); Museu Casa de Portinari (museum, mile 268, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.