Guarujá to Nova Serrana Road Trip: Route, Stops & Drive Time

By admin, 13 October, 2026

The Wayro route from Guarujá to Nova Serrana is 393 miles (632 km), about 8 h 55 min of driving without stops.

U.S. State Department travel advisory: Brazil — Level 2, Exercise Increased Caution
  • Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).

Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
Sabina Escola Parque do ConhecimentoMuseu de Santo AndréBotanical Garden of São PauloOrthodox Metropolitan Cathedral of São PauloMuseum of the Military Police of the state of São PauloOur Lady of the Conception Cathedral, GuarulhosHoly Spirit Cathedral, DivinópolisGuarujáNova Serrana
Route from Guarujá to Nova Serrana with the 7 stops listed below (blue dots).
Distance by road393 mi (632 km)
Drive time without stops8 h 55 min
Main roads, in orderSPA-248/055 → SP-150 → SP-010 → SP-008 → BR-381 → BR-494 → BR-262
States on the routeSão Paulo, Minas Gerais
Fuel estimate (car at 25 mpg)about 15.7 gal; actual use varies by vehicle and traffic
Stops listed below7

Driving Guarujá to Nova Serrana: the shape of the trip

SP-008 (154 mi) and BR-381 (85 mi) carry about 61% of the 393 miles. It runs through 2 states: São Paulo, Minas Gerais. None of the 7 stops below is right on the road, so plan each as a short side trip.

Roads you'll take from Guarujá to Nova Serrana

RoadRoute miles (from–to)Length, miState
local roads0–11São Paulo
SPA-248/0551–1918São Paulo
connecting roads19–201São Paulo
SP-15020–4828São Paulo
connecting roads48–502São Paulo
local roads50–566São Paulo
connecting roads56–593São Paulo
SP-01059–8021São Paulo
SP-00880–234154São Paulo, Minas Gerais
BR-381234–31985Minas Gerais
BR-494319–38667Minas Gerais
connecting roads386–3871Minas Gerais
BR-262387–3914Minas Gerais
local roads391–3932Minas Gerais
  • Mile 116 of this route: São Paulo → Minas Gerais (state line)

Breaking up the drive: stops between Guarujá and Nova Serrana

  • Nature and outdoors: Botanical Garden of São Paulo (mile 47)
  • Museums and history: Sabina Escola Parque do Conhecimento (mile 42), Museu de Santo André (mile 43), Botanical Garden of São Paulo (mile 47), Orthodox Metropolitan Cathedral of São Paulo (mile 50), Museum of the Military Police of the state of São Paulo (mile 55), Our Lady of the Conception Cathedral, Guarulhos (mile 60), Holy Spirit Cathedral, Divinópolis (mile 367)
  • With kids: Sabina Escola Parque do Conhecimento (mile 42)

Sabina Escola Parque do Conhecimento

Mile 42 · Science museum · 2 mi from the route · side trip; actual detour depends on access roads

Sabina Escola Parque do Conhecimento is a science museum in Santo André, in Greater São Paulo, and one of the area's planetarium venues.

Museu de Santo André

Mile 43 · History museum · 3 mi from the route · side trip; actual detour depends on access roads

Museu de Santo André Dr. Octaviano Armando Gaiarsa is one of the main museums in the city of Santo André, São Paulo.

Botanical Garden of São Paulo

Mile 47 · Museum · 2 mi from the route

Next to the São Paulo Zoo, the Botanical Garden of São Paulo spans 406 acres inside Fontes do Ipiranga State Park, in the Água Funda district of the city's South Zone.

Orthodox Metropolitan Cathedral of São Paulo

Mile 50 · Cathedral · 3 mi from the route · side trip; actual detour depends on access roads

On Rua Vergueiro in the Paraíso area of São Paulo, the Orthodox Metropolitan Cathedral belongs to the Greek Orthodox Church of Antioch and is dedicated to Paul the Apostle.

Museum of the Military Police of the state of São Paulo

Mile 55 · Police museum · 3 mi from the route · side trip; actual detour depends on access roads

Founded in 1958, this São Paulo museum preserves and exhibits the history and material heritage of the state's Military Police and the forces that came before it.

Our Lady of the Conception Cathedral, Guarulhos

Mile 60 · Cathedral · 2 mi from the route

Also called Guarulhos Cathedral, this Catholic church was built in 1665 in the center of Guarulhos, São Paulo state.

Holy Spirit Cathedral, Divinópolis

Mile 367 · Cathedral · 2 mi from the route · side trip; actual detour depends on access roads

The Holy Spirit Cathedral in Divinópolis, Minas Gerais, is the Roman Catholic church that serves as seat of the Diocese of Divinópolis.

More drives to Nova Serrana

From Guarujá to other places in Brazil

Frequently asked questions

How long does it take to drive from Guarujá to Nova Serrana?

About 8 h 55 min of driving without stops, over 393 miles.

How far is Nova Serrana from Guarujá by car?

About 393 miles (632 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Is it safe to drive from Guarujá to Nova Serrana?

The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Guarujá to Nova Serrana use?

In order: SPA-248/055, SP-150, SP-010, SP-008, BR-381, BR-494 and BR-262. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Guarujá to Nova Serrana?

Closest to the road: Botanical Garden of São Paulo (museum, mile 47, 2 mi from the route); Our Lady of the Conception Cathedral, Guarulhos (cathedral, mile 60, 2 mi from the route); Holy Spirit Cathedral, Divinópolis (cathedral, mile 367, 2 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.