Plan on about 10 h 49 min of driving for the 526-mile (846 km) trip from Florianópolis to Presidente Prudente, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Flooding makes some roads through the Amazon impassable for much of the year.”
| Distance by road | 526 mi (846 km) |
|---|---|
| Drive time without stops | 10 h 49 min |
| Main roads, in order | BR-282 → BR-101 → BR-376 → BR-116 → BR-277 → PR-445 → PR-090 → SP-421 → SP-483 → SP-270 |
| States on the route | Santa Catarina, Paraná, São Paulo |
| Fuel estimate (car at 25 mpg) | about 21.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
What the drive from Florianópolis to Presidente Prudente is like
BR-376 (166 mi) and BR-101 (127 mi) carry about 56% of the 526 miles. It runs through 3 states: Santa Catarina, Paraná, São Paulo. Of the 9 stops listed below, 2 are within a mile of the road.
Road-by-road breakdown: Florianópolis to Presidente Prudente
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–2 | 2 | |
| BR-282 | 2–5 | 3 | Santa Catarina |
| connecting roads | 5–6 | 1 | Santa Catarina |
| BR-101 | 6–133 | 127 | Santa Catarina |
| BR-376 | 133–175 | 42 | Santa Catarina, Paraná |
| connecting roads | 175–176 | 1 | Paraná |
| BR-116 | 176–183 | 7 | Paraná |
| BR-277 | 183–253 | 70 | Paraná |
| BR-376 | 253–377 | 124 | Paraná |
| PR-445 | 377–452 | 75 | Paraná |
| PR-090 | 452–482 | 30 | Paraná |
| SP-421 | 482–504 | 22 | Paraná, São Paulo |
| SP-483 | 504–510 | 6 | São Paulo |
| SP-270 | 510–524 | 14 | São Paulo |
| local roads | 524–526 | 2 | São Paulo |
- Mile 134 of this route: Santa Catarina → Paraná (state line)
- Mile 483 of this route: Paraná → São Paulo (state line)
Where to stop on the way to Presidente Prudente
- Right off the route (under 1 mile): Praia do Estaleirinho (mile 45), Teatro Positivo (mile 191)
- Nature and outdoors: Praia do Estaleirinho (mile 45), Guaricana National Park (mile 145)
- Museums and history: Estação da Memória (mile 106), Museu de Arqueologia de Ponta Grossa (mile 255), Sacred Heart of Jesus Cathedral, Londrina (mile 424), Museu de Arte de Londrina (mile 424)
Praia do Estaleirinho
The first of six beaches along Balneário Camboriú's Interpraias road, Praia do Estaleirinho has coarse sand and plenty of waves, and sits a little over 10 km from downtown.
Estação da Memória
Housed in Joinville's former railroad station, built in 1906, Estação da Memória showcases German-Brazilian architecture and the railway heritage that shaped the city's growth and industrialization.
Guaricana National Park
Created in 2014, Guaricana National Park protects about 49,300 hectares of the Serra do Mar in Paraná, across Guaratuba, Morretes and São José dos Pinhais.
Teatro Positivo
Set inside the Universidade Positivo campus in Curitiba, Paraná, Teatro Positivo is a performance hall with seating for 2,400 people.
Museu de Arqueologia de Ponta Grossa
Officially the Museu de Arqueologia Ciro Flamarion Cardoso, this Ponta Grossa museum opened in 2001 and holds objects on the history, art and archaeology of ancient Egypt.
Cineteatro Ópera
Ponta Grossa's Cineteatro Ópera is a performance venue with three auditoriums totaling 933 seats, the main hall holding about 690 people.
Teatro Marista
Teatro Marista is a performance venue in Ponta Grossa, Paraná, with seating for 753 people; it is run by the Colégio Marista Pio XII, which also has a 210-seat amphitheater.
Sacred Heart of Jesus Cathedral, Londrina
Also called Londrina Cathedral, the Sacred Heart of Jesus Cathedral is a Catholic church in the center of Londrina, in northern Paraná.
Museu de Arte de Londrina
The Museu de Arte de Londrina is an art museum in Londrina, Paraná, created by municipal decree and opened on May 12, 1993.
When you get to Presidente Prudente
Teatro Municipal Procópio Ferreira
Named after actor Procópio Ferreira, this municipal theater in Presidente Prudente, São Paulo state, is the city's most-used public venue.
More drives to Presidente Prudente
- Araraquara to Presidente Prudente
- Limeira to Presidente Prudente
- Campinas to Presidente Prudente
- Jundiaí to Presidente Prudente
- Mogi das Cruzes to Presidente Prudente
- São Vicente to Presidente Prudente
From Florianópolis to other places in Brazil
- Florianópolis to Jaraguá do Sul
- Florianópolis to Paranaguá
- Florianópolis to Ponta Grossa
- Florianópolis to Caxias do Sul
- Florianópolis to Novo Hamburgo
- Florianópolis to Bento Gonçalves
Frequently asked questions
How long is the drive from Florianópolis to Presidente Prudente?
About 10 h 49 min of driving without stops, over 526 miles.
How far is Presidente Prudente from Florianópolis by car?
About 526 miles (846 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Florianópolis to Presidente Prudente?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from Florianópolis to Presidente Prudente?
In order: BR-282, BR-101, BR-376, BR-116, BR-277, PR-445, PR-090, SP-421, SP-483 and SP-270. The road-by-road table above shows the route miles for each one.
What are good stops between Florianópolis and Presidente Prudente?
Closest to the road: Praia do Estaleirinho (beach, mile 45, 0.7 mi from the route); Estação da Memória (museum, mile 106, 1 mi from the route); Teatro Positivo (theater, mile 191, 0.4 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.