Cusco to Tacna Road Trip: Route, Stops & Drive Time

By admin, 13 October, 2026

The Wayro route from Cusco to Tacna is 558 miles (898 km), about 15 h 10 min of driving without stops.

U.S. State Department travel advisory: Peru — Level 2, Exercise Increased Caution

Full advisory: Peru. Advisory issued: Peru September 04, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Peru: “Due to road safety risks, U.S. government employees working in Peru are prohibited from nighttime driving.”
SillkinchaniAyamachayYura Hot SpringsTeatro Municipal, ArequipaZona Monumental de YanahuaraIslayCuscoTacna
Route from Cusco to Tacna with the 6 stops listed below (blue dots).
Distance by road558 mi (898 km)
Time at the wheel, no stops15 h 10 min
Main roads, in orderPE-3S → CU-117 → CU-1627 → PE-34F → CU-126 → CU-130 → PE-34E → PE-34A → PE-34 → PE-1SD
Regions on the routeCusco, Arequipa, Moquegua, Tacna
Fuel estimate (car at 25 mpg)about 22.3 gal; actual use varies by vehicle and traffic
Stops listed below6

The Cusco–Tacna drive in a few lines

PE-34E (127 mi) and PE-1SD (85 mi) carry about 38% of the 558 miles. It runs through 4 regions: Cusco, Arequipa, Moquegua, Tacna. Of the 6 stops listed below, 3 are within a mile of the road.

Which roads connect Cusco and Tacna

RoadRoute miles (from–to)Length, miRegion
local roads0–88Cusco
PE-3S8–5547Cusco
CU-11755–594Cusco
CU-162759–7011Cusco
PE-34F70–777Cusco
connecting roads77–781Cusco
local roads78–813Cusco
CU-12681–9110Cusco
CU-13091–13544Cusco
connecting roads135–1383Cusco
PE-34E138–265127Cusco, Arequipa
PE-34A265–30338Arequipa
local roads303–3074Arequipa
connecting roads307–3081Arequipa
PE-34A308–33426Arequipa
local roads334–34410Arequipa
PE-34344–37733Arequipa
PE-1SD377–46285Arequipa, Moquegua
local roads462–55896Moquegua, Tacna
  • Mile 167 of this route: Cusco → Arequipa (region line)
  • Mile 175 of this route: Arequipa → Cusco (region line)
  • Mile 180 of this route: Cusco → Arequipa (region line)
  • Mile 432 of this route: Arequipa → Moquegua (region line)
  • Mile 484 of this route: Moquegua → Tacna (region line)

Where to stop on the way to Tacna

  • Right off the route (under 1 mile): Sillkinchani (mile 8), Yura Hot Springs (mile 297), Zona Monumental de Yanahuara (mile 311)
  • Nature and outdoors: Yura Hot Springs (mile 297)
  • Museums and history: Sillkinchani (mile 8), Ayamachay (mile 70), Zona Monumental de Yanahuara (mile 311), Islay (mile 378)

Sillkinchani

Mile 8 · Archaeological site · 0.2 mi from the route

About 7 km southeast of Cusco, on an east-facing slope between Saylla and San Jerónimo districts, Sillkinchani is an archaeological site occupied from the Late Intermediate Period through the Late Horizon.

Ayamachay

Mile 70 · Archaeological site · 2 mi from the route

Ayamachay is an archaeological site with rock paintings in the Combapata District of Cusco's Canchis Province, above the left bank of the Salcca River near the village of Oroscocha.

Yura Hot Springs

Mile 297 · Hot spring · 1 mi from the route

Roughly 28 km north-northwest of Arequipa, the Yura Hot Springs (Baños termales de Yura) are a thermal bathing complex in the Yura district.

Teatro Municipal, Arequipa

Mile 311 · Theater · 3 mi from the route · side trip; actual detour depends on access roads

Opened in 1940 on calle Mercaderes in historic Arequipa, the Teatro Municipal seats 1,058 and was declared part of Peru's historic heritage in 1987.

Zona Monumental de Yanahuara

Mile 311 · Historic district · 0.9 mi from the route

The Zona Monumental de Yanahuara is the historic core of Yanahuara, in the district of the same name in Peru's Arequipa department.

Islay

Mile 378 · Archaeological site · 2 mi from the route

In the industrial heart of Matarani, Pueblo Viejo de Islay holds the ruins of a port town founded on August 30, 1827, as Arequipa's main port, replacing Quilca.

In Tacna itself

Tacna Cathedral

Cathedral · in Tacna

Next to the Paseo Cívico on San Martín Avenue, Tacna Cathedral is a Roman Catholic church in the center of the city.

Municipal Theatre of Tacna

Theater · in Tacna

In the center of Tacna, the Municipal Theatre of Tacna is the city's municipal stage for performances.

Casa Museo Basadre

Historic house museum · in Tacna

Facing the Paseo Cívico in Tacna, the Casa Museo Basadre was the home of Tacna-born historian Jorge Basadre Grohmann.

More drives to Tacna

From Cusco to other places in Peru

Frequently asked questions

How long is the drive from Cusco to Tacna?

About 15 h 10 min of driving without stops, over 558 miles.

How far is Tacna from Cusco by car?

About 558 miles (898 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

What does the U.S. travel advisory say about the Cusco to Tacna drive?

The U.S. State Department rates Peru Level 2: Exercise Increased Caution. Read the full advisory before you go.

Which highways go from Cusco to Tacna?

In order: PE-3S, CU-117, CU-1627, PE-34F, CU-126, CU-130, PE-34E, PE-34A, PE-34 and PE-1SD. The road-by-road table above shows the route miles for each one.

What are good stops between Cusco and Tacna?

Closest to the road: Sillkinchani (archaeological site, mile 8, 0.2 mi from the route); Yura Hot Springs (hot spring, mile 297, 1 mi from the route); Zona Monumental de Yanahuara (historic district, mile 311, 0.9 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.