The Wayro route from Colonia del Sacramento to Fray Marcos is 152 miles (244 km), about 3 h 29 min of driving without stops.
Full advisory: Uruguay. Advisory issued: Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “Several of the main highways are particularly accident-ridden.”
| Distance by road | 152 mi (244 km) |
|---|---|
| Driving time, no stops | 3 h 29 min |
| Departments on the route | Colonia, San José, Canelones, Florida |
| Fuel estimate (car at 25 mpg) | about 6.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
Driving Colonia del Sacramento to Fray Marcos: the shape of the trip
It runs through 4 departments: Colonia, San José, Canelones, Florida. Of the 4 stops listed below, 3 are within a mile of the road.
The route from Colonia del Sacramento to Fray Marcos, road by road
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–46 | 46 | Colonia, San José |
| connecting roads | 46–47 | 1 | San José |
| local roads | 47–68 | 21 | San José |
| connecting roads | 68–71 | 3 | San José |
| local roads | 71–114 | 43 | San José, Canelones |
| connecting roads | 114–117 | 3 | Canelones |
| local roads | 117–124 | 7 | Canelones |
| connecting roads | 124–125 | 1 | Canelones |
| local roads | 125–152 | 27 | Canelones, Florida |
- Mile 45 of this route: Colonia → San José (department line)
- Mile 93 of this route: San José → Canelones (department line)
- Mile 150 of this route: Canelones → Florida (department line)
Places worth a stop between Colonia del Sacramento and Fray Marcos
- Right off the route (under 1 mile): Cathedral of San José de Mayo (mile 68), Museo Departamental de San José (mile 68), Cathedral of Our Lady of Guadalupe (mile 103)
- Museums and history: Museum of Rosario Mural Art (mile 30), Cathedral of San José de Mayo (mile 68), Museo Departamental de San José (mile 68), Cathedral of Our Lady of Guadalupe (mile 103)
Museum of Rosario Mural Art
Rather than a building, the Museum of Rosario Mural Art is a circuit of history-themed murals spread around Rosario, in Uruguay's Colonia department.
Cathedral of San José de Mayo
The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.
Museo Departamental de San José
Set in central San José de Mayo, the Museo Departamental de San José is a history and fine arts museum that also runs a library, archives and cultural programs.
Cathedral of Our Lady of Guadalupe
Construction of Canelones' Cathedral of Our Lady of Guadalupe began in 1816; the church became a cathedral in 1961 and Uruguay's national shrine of Our Lady of Guadalupe in 2020.
More drives to Fray Marcos
- Nueva Helvecia to Fray Marcos
- Carmelo to Fray Marcos
- Paysandú to Fray Marcos
- Rivera to Fray Marcos
- Salto to Fray Marcos
- Artigas to Fray Marcos
From Colonia del Sacramento to other places in Uruguay
- Colonia del Sacramento to Veinticinco de Agosto
- Colonia del Sacramento to Alejandro Gallinal
- Colonia del Sacramento to Barra de Valizas
- Colonia del Sacramento to Punta del Diablo
- Colonia del Sacramento to Chuy
- Colonia del Sacramento to Treinta y Tres
Frequently asked questions
How long does it take to drive from Colonia del Sacramento to Fray Marcos?
About 3 h 29 min of driving without stops, over 152 miles.
What is the driving distance from Colonia del Sacramento to Fray Marcos?
About 152 miles (244 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Colonia del Sacramento to Fray Marcos drive?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What are good stops between Colonia del Sacramento and Fray Marcos?
Closest to the road: Museo Departamental de San José (history museum, mile 68, 0.7 mi from the route); Cathedral of San José de Mayo (cathedral, mile 68, 0.9 mi from the route); Cathedral of Our Lady of Guadalupe (cathedral, mile 103, 0.0 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.