Plan on about 7 h 16 min of driving for the 423-mile (680 km) trip from Cárdenas to Zacatlán, before any stops.
| Total distance | 423 mi (680 km) |
|---|---|
| Drive time without stops | 7 h 16 min |
| Main roads, in order | MEX-180 → MEX-180D → MEX-145D → MEX-150D → MEX-136 → MEX-119 |
| Mexican states on the route | Tabasco, Veracruz, Puebla, Tlaxcala |
| Toll roads (as marked in OpenStreetMap) | MEX-180D, MEX-145D, MEX-150D |
| Fuel estimate (car at 25 mpg) | about 16.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
The Cárdenas–Zacatlán drive in a few lines
MEX-145D (142 mi) and MEX-150D (87 mi) carry about 54% of the 423 miles. It runs through 4 states: Tabasco, Veracruz, Puebla, Tlaxcala. OpenStreetMap marks tolled sections on MEX-180D, MEX-145D and MEX-150D. Of the 8 stops listed below, 2 are within a mile of the road.
Which roads connect Cárdenas and Zacatlán
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| MEX-180 | 0–11 | 11 | Tabasco |
| MEX-180D | 11–44 | 33 | Tabasco |
| MEX-180 | 44–63 | 19 | Tabasco, Veracruz |
| MEX-180D | 63–85 | 22 | Veracruz |
| MEX-145D | 85–227 | 142 | Veracruz |
| MEX-150D | 227–314 | 87 | Veracruz, Puebla |
| local roads | 314–354 | 40 | Puebla |
| MEX-136 | 354–377 | 23 | Tlaxcala |
| connecting roads | 377–380 | 3 | Tlaxcala |
| MEX-119 | 380–423 | 43 | Tlaxcala, Puebla |
- Mile 47 of this route: Tabasco → Veracruz (state line)
- Mile 295 of this route: Veracruz → Puebla (state line)
- Mile 354 of this route: Puebla → Tlaxcala (state line)
- Mile 399 of this route: Tlaxcala → Puebla (state line)
What to see on the way from Cárdenas to Zacatlán
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 282), Museo Nacional del Títere (mile 362)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 282)
- Museums and history: La Venta (mile 44), Huatusco (mile 234), Cathedral of Córdoba, Veracruz (mile 260), Veracruz State Art Museum (mile 272), Orizaba Cathedral (mile 273), Museo Nacional del Títere (mile 362)
La Venta
More than 200 artifacts fill the site museum at La Venta, among them massive sandstone sculptures discovered at the base of the main pyramid. The once-important Olmec city lies in Tabasco, near Huimanguillo.
Huatusco
Getting to the ruins of Huatusco (Cuauhtochco) means crossing a suspension bridge and hiking a steep trail; a local guide is a good idea, and there are no visitor facilities. The Mexica-era temple keeps its original finishes.
Cathedral of Córdoba, Veracruz
An octagonal dome covered in tiles crowns Córdoba's Immaculate Conception Cathedral, the city's main church, finished in a neoclassical style.
Veracruz State Art Museum
Housed in Orizaba's 18th-century former Oratorio of San Felipe Neri, later a hospital and then a jail, the Veracruz State Art Museum (Museo de Arte del Estado) holds more than 700 works, including 36 by Diego Rivera.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Protected as a national park by Mexico's government, Cañón del Río Blanco is a natural area in Veracruz state.
Museo Nacional del Títere
On the main square of Huamantla, the National Puppet Museum (Museo Nacional del Títere) fills eight galleries with puppets from Mexico and abroad, including pieces tied to the Rosete Aranda family, whose company toured Mexico for generations.
Santuario de Nuestro Padre Jesús de Aquixtla
In the Sierra Norte de Puebla, the sanctuary of Nuestro Padre Jesús in Aquixtla draws thousands of pilgrims during the year who come to give thanks for favors received.
More drives to Zacatlán
- Chiautempan to Zacatlán
- Zacatelco to Zacatlán
- Pachuca to Zacatlán
- Cholula to Zacatlán
- Atlixco to Zacatlán
- Mexico City to Zacatlán
From Cárdenas to other places in Mexico
- Cárdenas to Zacatelco
- Cárdenas to Chiautempan
- Cárdenas to Huejotzingo
- Cárdenas to Tlaxcala
- Cárdenas to Calpulalpan
- Cárdenas to Ocuituco
Frequently asked questions
How long is the drive from Cárdenas to Zacatlán?
About 7 h 16 min of driving without stops, over 423 miles.
What is the driving distance from Cárdenas to Zacatlán?
About 423 miles (680 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Cárdenas to Zacatlán?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Cárdenas to Zacatlán?
The U.S. State Department rates Tabasco Level 2: Exercise Increased Caution; Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Cárdenas to Zacatlán use?
In order: MEX-180, MEX-180D, MEX-145D, MEX-150D, MEX-136 and MEX-119. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Cárdenas to Zacatlán?
Closest to the road: Veracruz State Art Museum (art museum, mile 272, 1 mi from the route); Cañón del Río Blanco National Park (national park, mile 282, 0.5 mi from the route); Museo Nacional del Títere (museum, mile 362, 0.9 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.