Caraguatatuba to Assis Road Trip: Route & Stops

By admin, 13 October, 2026

Caraguatatuba to Assis is about 377 road miles (607 km): roughly 7 h 17 min at the wheel if you don't stop.

U.S. State Department travel advisory: Brazil — Level 2, Exercise Increased Caution
  • Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).

Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Brazil: “Road maintenance is inadequate in many areas.”
Anthropology Museum of the Paraíba ValleyEcological Park of TietêTeatro Padre BentoDesinfectório CentralTeatro SantanaMunicipal Market of LapaMuseu do Relógio Professor Dimas de Melo PimentaMuseu de Anatomia Humana da Universidade de São PauloMunicipal Museum of BarueriCaraguatatubaAssis
Route from Caraguatatuba to Assis with the 9 stops listed below (blue dots).
Distance by road377 mi (607 km)
Driving time, no stops7 h 17 min
Main roads, in orderSPI-065/099 → SP-070 → SP-015 → SP-280 → SP-225 → SP-327 → SP-270
States on the routeSão Paulo
Fuel estimate (car at 25 mpg)about 15.1 gal; actual use varies by vehicle and traffic
Stops listed below9

How the Caraguatatuba to Assis drive plays out

SP-280 (184 mi) and SP-070 (53 mi) carry about 63% of the 377 miles. Of the 9 stops listed below, 5 are within a mile of the road.

Roads you'll take from Caraguatatuba to Assis

RoadRoute miles (from–to)Length, miState
local roads0–55São Paulo
SPI-065/0995–5045São Paulo
connecting roads50–511São Paulo
SP-07051–10453São Paulo
SP-015104–11713São Paulo
connecting roads117–1214São Paulo
SP-280121–305184São Paulo
connecting roads305–3061São Paulo
SP-225306–31812São Paulo
SP-327318–33820São Paulo
SP-270338–37436São Paulo
local roads374–3773São Paulo

Stops between Caraguatatuba and Assis

  • Right off the route (under 1 mile): Ecological Park of Tietê (mile 101), Desinfectório Central (mile 110), Municipal Market of Lapa (mile 114), Museu do Relógio Professor Dimas de Melo Pimenta (mile 117), Municipal Museum of Barueri (mile 127)
  • Nature and outdoors: Ecological Park of Tietê (mile 101)
  • Museums and history: Anthropology Museum of the Paraíba Valley (mile 62), Ecological Park of Tietê (mile 101), Desinfectório Central (mile 110), Museu do Relógio Professor Dimas de Melo Pimenta (mile 117), Museu de Anatomia Humana da Universidade de São Paulo (mile 118), Municipal Museum of Barueri (mile 127)

Anthropology Museum of the Paraíba Valley

Mile 62 · Museum · 2 mi from the route · side trip; actual detour depends on access roads

Housed in an 1857 mansion in Jacareí, the Anthropology Museum of the Paraíba Valley (Museu de Antropologia do Vale do Paraíba) shows sacred and folk art, paintings, and archaeological finds such as ceramic vessels and stone tools.

Ecological Park of Tietê

Mile 101 · Museum · 0.8 mi from the route

On the floodplain of the Tietê River, the Ecological Park of Tietê (Parque Ecológico do Tietê) is a park and environmental protection area run by the São Paulo state government's parks and partnerships office.

Teatro Padre Bento

Mile 101 · Theater · 2 mi from the route

Teatro Padre Bento is a theater in Guarulhos whose building is protected as heritage by both the São Paulo state heritage council and the city's own heritage council.

Desinfectório Central

Mile 110 · Museum · 0.6 mi from the route

Built in 1893 by the São Paulo state government to fight epidemics through disinfection, the Desinfectório Central was listed as heritage in 1985 and now houses the Emílio Ribas Museum of Public Health.

Teatro Santana

Mile 110 · Theater · 2 mi from the route

Teatro Santana is a theater in the city of São Paulo, a stop for anyone checking what is on stage while passing through.

Municipal Market of Lapa

Mile 114 · Market · 0.8 mi from the route

Opened on August 24, 1954, the Lapa Municipal Market (Mercadão da Lapa) is a landmark and tourist stop in Lapa, a neighborhood in São Paulo's west zone.

Museu do Relógio Professor Dimas de Melo Pimenta

Mile 117 · Museum · 0.6 mi from the route

This themed clock museum in Vila Leopoldina, in São Paulo's West Zone, traces the history and technology of timekeeping through many types of clocks, and links accurate time to weather forecasting.

Museu de Anatomia Humana da Universidade de São Paulo

Mile 118 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Founded by Professor Alfonso Bovero, the Museum of Human Anatomy of the University of São Paulo grew out of his teaching of anatomy and histology at the old medical school.

Municipal Museum of Barueri

Mile 127 · Museum · 0.5 mi from the route

In the Jardim Belval neighborhood of Barueri, the Oswaldo Abat Municipal Museum occupies a heritage building and holds Indigenous objects excavated at the Aldeia de Barueri, photographs and sculptures on local history.

Arriving in Assis

Estação de Assis

Museum · in Assis

Assis's railway station joined the company's trunk line in 1914 and got its current building in 1926; the original station was adapted as housing for traffic staff in 1927.

Museu de Arte Primitiva de Assis

Museum · in Assis

Assis's museum of primitive (naïve) art, founded by José Nazareno Mimessi, sits inside Parque do Buracão, an ecological park, in its own climate-controlled building opened in 1999. It is run by the city's culture department.

More drives to Assis

From Caraguatatuba to other places in Brazil

Frequently asked questions

How long is the drive from Caraguatatuba to Assis?

About 7 h 17 min of driving without stops, over 377 miles.

What is the driving distance from Caraguatatuba to Assis?

About 377 miles (607 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Is it safe to drive from Caraguatatuba to Assis?

The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Caraguatatuba to Assis use?

In order: SPI-065/099, SP-070, SP-015, SP-280, SP-225, SP-327 and SP-270. The road-by-road table above shows the route miles for each one.

What are good stops between Caraguatatuba and Assis?

Closest to the road: Desinfectório Central (museum, mile 110, 0.6 mi from the route); Museu do Relógio Professor Dimas de Melo Pimenta (museum, mile 117, 0.6 mi from the route); Municipal Museum of Barueri (museum, mile 127, 0.5 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.