Berisso to Treinta y Tres, Uruguay Road Trip: Border & Stops

By admin, 13 October, 2026

By road, Berisso and Treinta y Tres, Uruguay are about 556 miles (895 km) apart, or roughly 11 h 42 min of driving. You cross from Argentina into Uruguay at about mile 205, at the Gualeguaychú–Fray Bentos bridge.

U.S. State Department travel advisory: Argentina — Level 1, Exercise Normal Precautions; Uruguay — Level 2, Exercise Increased Caution

Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
  • Uruguay: “Illumination, pavement markings, and road surfaces for secondary roads can be poor.”
Centro Cultural General San MartínCasa Nacional del BicentenarioEduardo Sívori MuseumTemaikènGualeguaychú CathedralCathedral of MercedesCathedral of San José de MayoIglesia de Cristo Obrero y Nuestra Señora de LourdesSalto del PenitenteArgentina–Uruguay borderBerissoTreinta y Tres
Route from Berisso to Treinta y Tres with the 9 stops listed below (blue dots) and the approximate Argentina–Uruguay border crossing (red square).
Distance556 mi (895 km)
Time at the wheel, no stops11 h 42 min
Main roads, in order114-05 → RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN136
Border crossingabout mile 205, Argentina → Uruguay (the Gualeguaychú–Fray Bentos bridge)
Regions on the routeBuenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja, Treinta y Tres
Fuel estimate (car at 25 mpg)about 22.3 gal; actual use varies by vehicle and traffic
Stops listed below9

Getting across the Argentina–Uruguay border

The route crosses at about mile 205, at the Gualeguaychú–Fray Bentos bridge, from Entre Ríos into Río Negro. Plan on two checks on each side: immigration for your passport and customs for the car.

Entering Uruguay (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date.
Driving in UruguayYou can drive on your U.S. license.
Entering Argentina (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps.
Driving in ArgentinaA valid U.S. license usually works; an International Driving Permit is recommended.
Rental carCross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book.

Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.

How the Berisso to Treinta y Tres drive plays out

RN12 (47 mi) and RN9 (40 mi) carry about 16% of the 556 miles. The first 205 miles are in Argentina; the last 351 are in Uruguay. It runs through 10 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja, Treinta y Tres. Of the 9 stops listed below, 5 are within a mile of the road.

Berisso to Treinta y Tres: the road sequence

RoadRoute miles (from–to)Length, miRegion
local roads0–11Buenos Aires
114-051–43Buenos Aires
connecting roads4–73Buenos Aires
RN17–3730Buenos Aires, Ciudad de Buenos Aires
local roads37–403Ciudad de Buenos Aires
AV1-N40–466Ciudad de Buenos Aires
connecting roads46–482Ciudad de Buenos Aires
RN948–8840Ciudad de Buenos Aires, Buenos Aires
RP688–935Buenos Aires
RN1293–14047Buenos Aires, Entre Ríos
RN14140–17636Entre Ríos
local roads176–1837Entre Ríos
RN136183–20219Entre Ríos
connecting roads202–2053Entre Ríos
local roads205–30196Río Negro, Soriano
connecting roads301–3021Soriano
local roads302–33937Colonia, San José
connecting roads339–3412San José
local roads341–556215San José, Canelones, Lavalleja, Treinta y Tres
  • Mile 33 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
  • Mile 49 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
  • Mile 110 of this route: Buenos Aires → Entre Ríos (region line)
  • Mile 205 of this route: Entre Ríos → Río Negro (international border)
  • Mile 221 of this route: Río Negro → Soriano (region line)
  • Mile 302 of this route: Soriano → Colonia (region line)
  • Mile 319 of this route: Colonia → San José (region line)
  • Mile 364 of this route: San José → Canelones (region line)
  • Mile 429 of this route: Canelones → Lavalleja (region line)
  • Mile 539 of this route: Lavalleja → Treinta y Tres (region line)

Places worth a stop between Berisso and Treinta y Tres

  • Right off the route (under 1 mile): Casa Nacional del Bicentenario (mile 40), Eduardo Sívori Museum (mile 43), Temaikèn (mile 71), Cathedral of Mercedes (mile 222), Cathedral of San José de Mayo (mile 339)
  • Nature and outdoors: Salto del Penitente (mile 464)
  • Museums and history: Centro Cultural General San Martín (mile 39), Casa Nacional del Bicentenario (mile 40), Eduardo Sívori Museum (mile 43), Gualeguaychú Cathedral (mile 182), Cathedral of Mercedes (mile 222), Cathedral of San José de Mayo (mile 339), Iglesia de Cristo Obrero y Nuestra Señora de Lourdes (mile 409)
  • With kids: Temaikèn (mile 71)

Centro Cultural General San Martín

Mile 39 · Art museum · 1 mi from the route

Run by the city government near Corrientes Avenue, the General San Martín Cultural Centre in Buenos Aires hosts a mix of cultural and artistic events.

Casa Nacional del Bicentenario

Mile 40 · Museum · 1 mi from the route

Part cultural center and part museum, the Casa Nacional del Bicentenario is located in the Recoleta section of Buenos Aires.

Eduardo Sívori Museum

Mile 43 · Art museum · 0.5 mi from the route

Named after painter Eduardo Sívori, this municipal museum of plastic arts in Buenos Aires opened in 1938.

Temaikèn

Mile 71 · Zoo · 0.6 mi from the route

Temaikèn is a zoo in Belén de Escobar, outside Buenos Aires, and the only zoo in Argentina accredited by the Association of Zoos and Aquariums.

Gualeguaychú Cathedral

Mile 182 · Cathedral · 1 mi from the route

St. Joseph's Cathedral, also called Gualeguaychú Cathedral, is the mother church of the Roman Catholic Diocese of Gualeguaychú in Argentina.

Cathedral of Mercedes

Mile 222 · Cathedral · 0.7 mi from the route

Dedicated to Our Lady of Mercy, this cathedral is the main Catholic church of Mercedes, Uruguay, and has been the seat of the Diocese of Mercedes since 1960.

Cathedral of San José de Mayo

Mile 339 · Cathedral · 0.9 mi from the route

The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.

Iglesia de Cristo Obrero y Nuestra Señora de Lourdes

Mile 409 · Church · 5 mi from the route · side trip; actual detour depends on access roads

Wavy brick walls and a rippling brick roof define this church in Estación Atlántida, along with an openwork brick bell tower and a baptistery set underground. Engineer Eladio Dieste designed it, and it opened in 1960.

Salto del Penitente

Mile 464 · Waterfall · 3 mi from the route · side trip; actual detour depends on access roads

Once you reach Treinta y Tres

Museo Agustín Araújo

Museum · in Treinta y Tres

Treinta y Tres's departmental fine arts museum, the Museo Agustín Araújo is a public museum in the city of Treinta y Tres, Uruguay.

More drives to Treinta y Tres

More drives from Berisso

Frequently asked questions

How long does it take to drive from Berisso to Treinta y Tres, Uruguay?

About 11 h 42 min of driving without stops, over 556 miles.

How far is Treinta y Tres, Uruguay from Berisso by car?

About 556 miles (895 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Where does the Berisso to Treinta y Tres drive cross the border?

At about mile 205, from Argentina into Uruguay, at the Gualeguaychú–Fray Bentos bridge.

What do U.S. citizens need to drive from Berisso into Uruguay?

No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)

Is it safe to drive from Berisso to Treinta y Tres, Uruguay?

The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Berisso to Treinta y Tres use?

In order: 114-05, RN1, AV1-N, RN9, RP6, RN12, RN14 and RN136. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Berisso to Treinta y Tres?

Closest to the road: Eduardo Sívori Museum (art museum, mile 43, 0.5 mi from the route); Temaikèn (zoo, mile 71, 0.6 mi from the route); Cathedral of Mercedes (cathedral, mile 222, 0.7 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.