The Wayro route from Berisso to Paysandú, Uruguay is 249 miles (400 km), about 4 h 48 min of driving without stops. You cross from Argentina into Uruguay at about mile 243, at the Colón–Paysandú bridge.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
- Uruguay: “Several of the main highways are particularly accident-ridden.”
| Total distance | 249 mi (400 km) |
|---|---|
| Drive time without stops | 4 h 48 min |
| Main roads, in order | 114-05 → RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN135 |
| Border crossing | about mile 243, Argentina → Uruguay (the Colón–Paysandú bridge) |
| Regions on the route | Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Paysandú |
| Fuel estimate (car at 25 mpg) | about 9.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 7 |
The border on the way to Paysandú
The route crosses at about mile 243, at the Colón–Paysandú bridge, from Entre Ríos into Paysandú. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
Driving Berisso to Paysandú: the shape of the trip
RN14 (94 mi) and RN12 (47 mi) carry about 57% of the 249 miles. The first 243 miles are in Argentina; the last 6 are in Uruguay. It runs through 4 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Paysandú. Of the 7 stops listed below, 4 are within a mile of the road.
Berisso to Paysandú: the road sequence
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–1 | 1 | Buenos Aires |
| 114-05 | 1–4 | 3 | Buenos Aires |
| connecting roads | 4–7 | 3 | Buenos Aires |
| RN1 | 7–37 | 30 | Buenos Aires, Ciudad de Buenos Aires |
| local roads | 37–40 | 3 | Ciudad de Buenos Aires |
| AV1-N | 40–46 | 6 | Ciudad de Buenos Aires |
| connecting roads | 46–48 | 2 | Ciudad de Buenos Aires |
| RN9 | 48–88 | 40 | Ciudad de Buenos Aires, Buenos Aires |
| RP6 | 88–93 | 5 | Buenos Aires |
| RN12 | 93–140 | 47 | Buenos Aires, Entre Ríos |
| RN14 | 140–234 | 94 | Entre Ríos |
| RN135 | 234–242 | 8 | Entre Ríos |
| local roads | 242–249 | 7 | Entre Ríos, Paysandú |
- Mile 33 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
- Mile 49 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
- Mile 110 of this route: Buenos Aires → Entre Ríos (region line)
- Mile 243 of this route: Entre Ríos → Paysandú (international border)
Breaking up the drive: stops between Berisso and Paysandú
- Right off the route (under 1 mile): Museo Ferroviario de Tolosa (mile 7), Illuminated Block (mile 38), Buenos Aires Japanese Gardens (mile 42), Museo Malvinas e Islas del Atlántico Sur (mile 46)
- Nature and outdoors: Buenos Aires Japanese Gardens (mile 42)
- Museums and history: Museo Ferroviario de Tolosa (mile 7), Illuminated Block (mile 38), Our Lady of Narek Cathedral, Buenos Aires (mile 42), Museo Malvinas e Islas del Atlántico Sur (mile 46), San Isidro Cathedral (mile 52)
- With kids: The Children's Republic (mile 10)
Museo Ferroviario de Tolosa
Run by the Tolosa branch of the Ferroclub Argentino, created in 1996, the Museo Ferroviario "Ing. Pedro C. Saccaggio" is a railway museum in Tolosa.
The Children's Republic
Spread over 131 acres in La Plata, The Children's Republic is a theme park with 35 scale-model buildings.
Illuminated Block
The Illuminated Block (Manzana de las Luces) is a historical landmark in the Monserrat neighborhood of Buenos Aires, Argentina.
Our Lady of Narek Cathedral, Buenos Aires
On Charcas Street in Buenos Aires, the Armenian Cathedral of Our Lady of Narek is an Armenian Catholic church following the Armenian rite in full communion with the Pope.
Buenos Aires Japanese Gardens
Run by the Japanese Argentine Cultural Foundation, the Buenos Aires Japanese Gardens are a public space ranked among the largest Japanese gardens outside Japan.
Museo Malvinas e Islas del Atlántico Sur
Opened in June 2014 by the Argentine government, the Malvinas and South Atlantic Islands Museum stands on the former Navy Mechanics School grounds in Buenos Aires.
San Isidro Cathedral
Main church of the Diocese of San Isidro, this cathedral stands on Del Libertador Avenue opposite Plaza Mitre, in the historic quarter of San Isidro in Buenos Aires province.
In Paysandú itself
Nuestra Señora del Rosario y San Benito de Palermo, Paysandú
Paysandú's Catholic parish church of Our Lady of the Rosary and St. Benedict of Palermo was named a minor basilica in 1949 and remains an active parish of the city.
Teatro Florencio Sánchez
In the city of Paysandú, Teatro Florencio Sánchez is a theater and movie house that has been declared a national historic monument of Uruguay.
More drives to Paysandú
- Rivera to Paysandú
- Montevideo to Paysandú
- Buenos Aires to Paysandú, Uruguay
- Mar del Plata to Paysandú, Uruguay
- La Plata to Paysandú, Uruguay
- Porto Alegre to Paysandú, Uruguay
More drives from Berisso
- Berisso to Adrogué
- Berisso to Tigre
- Berisso to San Antonio de Areco
- Berisso to Arrecifes
- Berisso to Martínez
- Berisso to Colón, Argentina
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Berisso to Paysandú, Uruguay?
About 4 h 48 min of driving without stops, over 249 miles.
What is the driving distance from Berisso to Paysandú, Uruguay?
About 249 miles (400 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Berisso to Paysandú drive cross the border?
At about mile 243, from Argentina into Uruguay, at the Colón–Paysandú bridge.
What do U.S. citizens need to drive from Berisso into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
What does the U.S. travel advisory say about the Berisso to Paysandú drive?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Berisso to Paysandú use?
In order: 114-05, RN1, AV1-N, RN9, RP6, RN12, RN14 and RN135. The road-by-road table above shows the route miles for each one.
What are good stops between Berisso and Paysandú?
Closest to the road: Illuminated Block (museum, mile 38, 0.5 mi from the route); Buenos Aires Japanese Gardens (japanese garden, mile 42, 0.6 mi from the route); Museo Malvinas e Islas del Atlántico Sur (museum, mile 46, 0.4 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.