Berisso to Fray Marcos, Uruguay Road Trip: Route & Border

By admin, 13 October, 2026

By road, Berisso and Fray Marcos, Uruguay are about 423 miles (680 km) apart, or roughly 9 h 2 min of driving. You cross from Argentina into Uruguay at about mile 205, at the Gualeguaychú–Fray Bentos bridge.

U.S. State Department travel advisory: Argentina — Level 1, Exercise Normal Precautions; Uruguay — Level 2, Exercise Increased Caution

Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
  • Uruguay: “Traffic fatalities are high in Uruguay.”
Museo Ferroviario de TolosaIlluminated BlockMuseo del HolocaustoJosé Hernández Folk Art MuseumTierra SantaMuseo Histórico Cornelio de SaavedraGualeguaychú CathedralCathedral of MercedesCathedral of Our Lady of GuadalupeArgentina–Uruguay borderBerissoFray Marcos
Route from Berisso to Fray Marcos with the 9 stops listed below (blue dots) and the approximate Argentina–Uruguay border crossing (red square).
Distance by road423 mi (680 km)
Driving time, no stops9 h 2 min
Main roads, in order114-05 → RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN136
Border crossingabout mile 205, Argentina → Uruguay (the Gualeguaychú–Fray Bentos bridge)
Regions on the routeBuenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Florida
Fuel estimate (car at 25 mpg)about 16.9 gal; actual use varies by vehicle and traffic
Stops listed below9

The border on the way to Fray Marcos

The route crosses at about mile 205, at the Gualeguaychú–Fray Bentos bridge, from Entre Ríos into Río Negro. Plan on two checks on each side: immigration for your passport and customs for the car.

Entering Uruguay (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date.
Driving in UruguayYou can drive on your U.S. license.
Entering Argentina (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps.
Driving in ArgentinaA valid U.S. license usually works; an International Driving Permit is recommended.
Rental carCross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book.

Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.

What the drive from Berisso to Fray Marcos is like

RN12 (47 mi) and RN9 (40 mi) carry about 21% of the 423 miles. The first 205 miles are in Argentina; the last 218 are in Uruguay. It runs through 9 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Florida. Of the 9 stops listed below, 7 are within a mile of the road.

Roads you'll take from Berisso to Fray Marcos

RoadRoute miles (from–to)Length, miRegion
local roads0–11Buenos Aires
114-051–43Buenos Aires
connecting roads4–73Buenos Aires
RN17–3730Buenos Aires, Ciudad de Buenos Aires
local roads37–403Ciudad de Buenos Aires
AV1-N40–466Ciudad de Buenos Aires
connecting roads46–482Ciudad de Buenos Aires
RN948–8840Ciudad de Buenos Aires, Buenos Aires
RP688–935Buenos Aires
RN1293–14047Buenos Aires, Entre Ríos
RN14140–17636Entre Ríos
local roads176–1837Entre Ríos
RN136183–20219Entre Ríos
connecting roads202–2053Entre Ríos
local roads205–30196Río Negro, Soriano
connecting roads301–3021Soriano
local roads302–33937Colonia, San José
connecting roads339–3412San José
local roads341–38544San José, Canelones
connecting roads385–3883Canelones
local roads388–42335Canelones, Florida
  • Mile 33 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
  • Mile 49 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
  • Mile 110 of this route: Buenos Aires → Entre Ríos (region line)
  • Mile 205 of this route: Entre Ríos → Río Negro (international border)
  • Mile 221 of this route: Río Negro → Soriano (region line)
  • Mile 302 of this route: Soriano → Colonia (region line)
  • Mile 319 of this route: Colonia → San José (region line)
  • Mile 364 of this route: San José → Canelones (region line)
  • Mile 421 of this route: Canelones → Florida (region line)

What to see on the way from Berisso to Fray Marcos

  • Right off the route (under 1 mile): Museo Ferroviario de Tolosa (mile 7), Illuminated Block (mile 38), Museo del Holocausto (mile 40), José Hernández Folk Art Museum (mile 42), Tierra Santa (mile 44), Cathedral of Mercedes (mile 222), Cathedral of Our Lady of Guadalupe (mile 373)
  • Museums and history: Museo Ferroviario de Tolosa (mile 7), Illuminated Block (mile 38), Museo del Holocausto (mile 40), José Hernández Folk Art Museum (mile 42), Museo Histórico Cornelio de Saavedra (mile 48), Gualeguaychú Cathedral (mile 182), Cathedral of Mercedes (mile 222), Cathedral of Our Lady of Guadalupe (mile 373)
  • With kids: Tierra Santa (mile 44)

Museo Ferroviario de Tolosa

Mile 7 · Railway museum · 0.8 mi from the route

Run by the Tolosa branch of the Ferroclub Argentino, created in 1996, the Museo Ferroviario "Ing. Pedro C. Saccaggio" is a railway museum in Tolosa.

Illuminated Block

Mile 38 · Museum · 0.5 mi from the route

The Illuminated Block (Manzana de las Luces) is a historical landmark in the Monserrat neighborhood of Buenos Aires, Argentina.

Museo del Holocausto

Mile 40 · History museum · 0.8 mi from the route

Dedicated to keeping the memory of the Shoah alive, the Museo del Holocausto in Buenos Aires holds documents and personal objects donated by survivors who emigrated from Europe.

José Hernández Folk Art Museum

Mile 42 · Art museum · 0.6 mi from the route

Part of the city's public museum network, Buenos Aires' José Hernández Folk Art Museum collects, studies and displays Argentine folk art in its many forms.

Tierra Santa

Mile 44 · Theme park · 0.2 mi from the route

Tierra Santa is a religious theme park in the city of Buenos Aires, in Argentina.

Museo Histórico Cornelio de Saavedra

Mile 48 · History museum · 2 mi from the route · side trip; actual detour depends on access roads

Inside Parque General Paz on Avenida Crisólogo Larralde, the Cornelio de Saavedra Historical Museum is a history museum of the City of Buenos Aires.

Gualeguaychú Cathedral

Mile 182 · Cathedral · 1 mi from the route

St. Joseph's Cathedral, also called Gualeguaychú Cathedral, serves as the cathedral church of the Roman Catholic Diocese of Gualeguaychú in Argentina.

Cathedral of Mercedes

Mile 222 · Cathedral · 0.7 mi from the route

Mercedes, Uruguay, centers its Catholic life on the Cathedral of Our Lady of Mercy, which became the seat of the local diocese in 1960.

Cathedral of Our Lady of Guadalupe

Mile 373 · Cathedral · 0.1 mi from the route

Construction of Canelones' Cathedral of Our Lady of Guadalupe began in 1816; the church became a cathedral in 1961 and Uruguay's national shrine of Our Lady of Guadalupe in 2020.

More drives to Fray Marcos

More drives from Berisso

Frequently asked questions

How long does it take to drive from Berisso to Fray Marcos, Uruguay?

About 9 h 2 min of driving without stops, over 423 miles.

What is the driving distance from Berisso to Fray Marcos, Uruguay?

About 423 miles (680 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Where does the Berisso to Fray Marcos drive cross the border?

At about mile 205, from Argentina into Uruguay, at the Gualeguaychú–Fray Bentos bridge.

What do U.S. citizens need to drive from Berisso into Uruguay?

No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)

What does the U.S. travel advisory say about the Berisso to Fray Marcos drive?

The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Berisso to Fray Marcos use?

In order: 114-05, RN1, AV1-N, RN9, RP6, RN12, RN14 and RN136. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Berisso to Fray Marcos?

Closest to the road: Illuminated Block (museum, mile 38, 0.5 mi from the route); Tierra Santa (theme park, mile 44, 0.2 mi from the route); Cathedral of Our Lady of Guadalupe (cathedral, mile 373, 0.1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.