Plan on about 9 h 1 min of driving for the 414-mile (666 km) trip from Artigas to Piriápolis, before any stops.
Full advisory: Uruguay. Advisory issued: Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “Several of the main highways are particularly accident-ridden.”
| Distance | 414 mi (666 km) |
|---|---|
| Time at the wheel, no stops | 9 h 1 min |
| Departments on the route | Artigas, Salto, Rivera, Tacuarembó, Durazno, Florida, Canelones, Maldonado |
| Fuel estimate (car at 25 mpg) | about 16.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
On the road from Artigas to Piriápolis
It runs through 8 departments: Artigas, Salto, Rivera, Tacuarembó, Durazno, Florida, Canelones, Maldonado. Of the 8 stops listed below, 5 are within a mile of the road.
Roads you'll take from Artigas to Piriápolis
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| local roads | 0–84 | 84 | Artigas, Salto, Rivera |
| connecting roads | 84–85 | 1 | Rivera |
| local roads | 85–376 | 291 | Rivera, Tacuarembó, Durazno, Florida, Canelones |
| connecting roads | 376–377 | 1 | Canelones |
| local roads | 377–414 | 37 | Canelones, Maldonado |
- Mile 45 of this route: Artigas → Salto (department line)
- Mile 58 of this route: Salto → Rivera (department line)
- Mile 107 of this route: Rivera → Tacuarembó (department line)
- Mile 217 of this route: Tacuarembó → Durazno (department line)
- Mile 265 of this route: Durazno → Florida (department line)
- Mile 330 of this route: Florida → Canelones (department line)
- Mile 400 of this route: Canelones → Maldonado (department line)
Stops between Artigas and Piriápolis
- Right off the route (under 1 mile): Museo de Artes Visuales de Tacuarembó (mile 127), Casa de Rivera, Durazno (mile 255), Cathedral of Florida (mile 309), Piedra Alta (mile 310), Cathedral of Our Lady of Guadalupe (mile 341)
- Nature and outdoors: Chorro de Agua Fría (mile 153), Laguna del Cisne (mile 376)
- Museums and history: Museo de Artes Visuales de Tacuarembó (mile 127), Casa de Rivera, Durazno (mile 255), Cathedral of Florida (mile 309), Piedra Alta (mile 310), Cathedral of Our Lady of Guadalupe (mile 341), Iglesia de Cristo Obrero y Nuestra Señora de Lourdes (mile 377)
Museo de Artes Visuales de Tacuarembó
The Museum of Visual Arts of Tacuarembó (Museo de Artes Visuales) is a museum in the city of Tacuarembó, Uruguay.
Chorro de Agua Fría
In Uruguay's Tacuarembó Department, Chorro de Agua Fría is a waterfall that drops roughly 14 meters, the highest uninterrupted fall in the country.
Casa de Rivera, Durazno
Facing Plaza Independencia in Durazno, the Casa de Fructuoso Rivera (Casa de Rivera) is one of the town's main heritage sites and now houses the department's historical museum.
Cathedral of Florida
Florida's cathedral basilica is also Uruguay's national shrine of the Virgin of the Thirty-Three, the country's patroness, and keeps the original image; look for its bronze door by sculptor José Belloni and his son Stelio, stained glass and domes.
Piedra Alta
On the banks of the Santa Lucía Chico River outside the city of Florida, Piedra Alta is a rock formation of historic importance that appears on the department's coat of arms and flag.
Cathedral of Our Lady of Guadalupe
Construction of Canelones' Cathedral of Our Lady of Guadalupe began in 1816; the church became a cathedral in 1961 and Uruguay's national shrine of Our Lady of Guadalupe in 2020.
Laguna del Cisne
Near Salinas in Canelones, Laguna del Cisne is a subtropical lagoon of about 1.8 km², fed by a watershed of some 50 km², that has supplied drinking water to the Costa de Oro area since 1970.
Iglesia de Cristo Obrero y Nuestra Señora de Lourdes
Wavy brick walls and a rippling brick roof define this church in Estación Atlántida, along with an openwork brick bell tower and a baptistery set underground. Engineer Eladio Dieste designed it, and it opened in 1960.
Arriving in Piriápolis
Cerro Pan de Azúcar Native Wildlife Breeding Station
Near Piriápolis in Maldonado, this breeding station for native wildlife on Cerro Pan de Azúcar is surrounded by native vegetation and offers guided visits, including a native wildlife trail and a path up the hill.
Museo ferroviario de Piriápolis
Near the Rambla de los Argentinos in Piriápolis, the Museo Ferroviario de Piriápolis is a railway museum on Armenia Street, across from the Argentino Hotel.
More drives to Piriápolis
- Paysandú to Piriápolis
- Tacuarembó to Piriápolis
- Salto to Piriápolis
- Rivera to Piriápolis
- Bella Unión to Piriápolis
- Montevideo to Piriápolis
From Artigas to other places in Uruguay
- Artigas to Mercedes, Uruguay
- Artigas to Carmelo
- Artigas to Colonia del Sacramento
- Artigas to Conchillas
- Artigas to Nueva Helvecia
- Artigas to Veinticinco de Agosto
Frequently asked questions
How long does it take to drive from Artigas to Piriápolis?
About 9 h 1 min of driving without stops, over 414 miles.
What is the driving distance from Artigas to Piriápolis?
About 414 miles (666 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Artigas to Piriápolis drive?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
Where can you stop on the way from Artigas to Piriápolis?
Closest to the road: Casa de Rivera, Durazno (historic house museum, mile 255, 0.3 mi from the route); Piedra Alta (historic site, mile 310, 0.4 mi from the route); Cathedral of Our Lady of Guadalupe (cathedral, mile 341, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.