The Wayro route from Zacualpan de Amilpas to San Francisco is 546 miles (878 km), about 9 h 41 min of driving without stops.
| Total distance | 546 mi (878 km) |
|---|---|
| Drive time without stops | 9 h 41 min |
| Main roads, in order | MEX-160 → MEX-160D → MEX-95D → MEX-106 → MEX-200 → EM 44 → MEX-55 → MEX-55D → MEX-15D → MEX-15 → MEX-70D → MEX-200D |
| Mexican states on the route | Morelos, State of Mexico, Michoacán, Jalisco, Nayarit |
| Toll roads (as marked in OpenStreetMap) | MEX-160D, MEX-95D, MEX-55D, MEX-15D |
| Fuel estimate (car at 25 mpg) | about 21.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
Driving Zacualpan de Amilpas to San Francisco: the shape of the trip
MEX-15D (321 mi) and MEX-55D (29 mi) carry about 64% of the 546 miles. It runs through 5 states: Morelos, State of Mexico, Michoacán, Jalisco, Nayarit. OpenStreetMap marks tolled sections on MEX-160D, MEX-95D and MEX-55D. Of the 9 stops listed below, 5 are within a mile of the road.
The route from Zacualpan de Amilpas to San Francisco, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–7 | 7 | Morelos |
| MEX-160 | 7–17 | 10 | Morelos |
| MEX-160D | 17–38 | 21 | Morelos |
| connecting roads | 38–39 | 1 | Morelos |
| MEX-95D | 39–49 | 10 | Morelos |
| connecting roads | 49–50 | 1 | Morelos |
| MEX-106 | 50–68 | 18 | Morelos, State of Mexico |
| MEX-200 | 68–72 | 4 | State of Mexico |
| local roads | 72–77 | 5 | State of Mexico |
| connecting roads | 77–80 | 3 | State of Mexico |
| EM 44 | 80–88 | 8 | State of Mexico |
| local roads | 88–93 | 5 | State of Mexico |
| MEX-55 | 93–104 | 11 | State of Mexico |
| MEX-55D | 104–133 | 29 | State of Mexico |
| MEX-55 | 133–137 | 4 | State of Mexico |
| MEX-15D | 137–393 | 256 | State of Mexico, Michoacán, Jalisco |
| MEX-15 | 393–402 | 9 | Jalisco |
| MEX-15D | 402–467 | 65 | Jalisco, Nayarit |
| local roads | 467–501 | 34 | Nayarit |
| MEX-70D | 501–519 | 18 | Nayarit |
| MEX-200D | 519–534 | 15 | Nayarit |
| MEX-200 | 534–545 | 11 | Nayarit |
| local roads | 545–546 | 1 | Nayarit |
- Mile 58 of this route: Morelos → State of Mexico (state line)
- Mile 155 of this route: State of Mexico → Michoacán (state line)
- Mile 323 of this route: Michoacán → Jalisco (state line)
- Mile 450 of this route: Jalisco → Nayarit (state line)
What to see on the way from Zacualpan de Amilpas to San Francisco
- Right off the route (under 1 mile): Tepoztlán Ex Convento Museum (mile 34), Lagunas de Zempoala National Park (mile 59), Cathedral of Atlacomulco (mile 134), Statue of Minerva, Guadalajara (mile 388), Museo Interpretativo del Paisaje Agavero y la Minería (mile 431)
- Nature and outdoors: Lagunas de Zempoala National Park (mile 59), Cumbres del Ajusco National Park (mile 61), Parque Walt Disney (mile 385), Rincón de Guayabitos (mile 530)
- Museums and history: Tepoztlán Ex Convento Museum (mile 34), Cathedral of Atlacomulco (mile 134), Museo de Cera (mile 386), Museo Interpretativo del Paisaje Agavero y la Minería (mile 431)
Tepoztlán Ex Convento Museum
Tepoztlán's Dominican monastery, built between 1555 and 1580, keeps original 16th-century murals in its cloister. Upstairs, the museum covers local daily life, faith, festivals and dances, and the complex is part of a UNESCO World Heritage listing.
Lagunas de Zempoala National Park
Seven lagoons, three of them permanent, sit among pine, oak and fir forest above 3,000 meters in this park, decreed in 1936 on the Morelos–State of Mexico line. Hiking, horseback riding, camping and rowboats are popular here.
Cumbres del Ajusco National Park
Pine and oak forests climb toward alpine meadows in Cumbres del Ajusco National Park, on Mexico City's southern edge. It draws hikers, climbers and cyclists, and it gets occasional snow, a rarity for the region.
Cathedral of Atlacomulco
Dedicated to Divine Providence, the cathedral in Atlacomulco is the principal Catholic church in town and the seat of the local diocese.
Parque Walt Disney
Despite sharing a name with Walt Disney, this recreational space in Guadalajara's Colonia Olímpica has no direct theme tied to Disney's amusement parks.
Museo de Cera
On the Plaza de la Liberación in downtown Guadalajara, the Museo de Cera has 12 rooms with more than 130 wax figures of athletes, singers, actors, politicians and religious figures. It opened in 1994.
Statue of Minerva, Guadalajara
At a roundabout fountain in Guadalajara, a bronze statue of Minerva, Roman goddess of wisdom, stands on a large pedestal inscribed with the names of 18 notable citizens.
Museo Interpretativo del Paisaje Agavero y la Minería
In the municipality of Magdalena, Mexico, an interpretive museum focuses on two subjects: the agave landscape and mining.
Rincón de Guayabitos
Visitors from Guadalajara and Tepic often head to this Nayarit beach town in the municipality of Compostela. Its shore runs about two kilometers, and the waves tend to be calm.
More drives to San Francisco
- La Manzanilla to San Francisco
- Barra de Navidad to San Francisco
- Tecomán to San Francisco
- San Juan de los Lagos to San Francisco
- Pénjamo to San Francisco
- León to San Francisco
From Zacualpan de Amilpas to other places in Mexico
- Zacualpan de Amilpas to Ixtenco
- Zacualpan de Amilpas to Omitlán
- Zacualpan de Amilpas to Tetela de Ocampo
- Zacualpan de Amilpas to Huasca de Ocampo
- Zacualpan de Amilpas to El Oro
- Zacualpan de Amilpas to Metztitlán
Continue Your Adventure
Frequently asked questions
How long is the drive from Zacualpan de Amilpas to San Francisco?
About 9 h 41 min of driving without stops, over 546 miles.
What is the driving distance from Zacualpan de Amilpas to San Francisco?
About 546 miles (878 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Zacualpan de Amilpas to San Francisco?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Zacualpan de Amilpas to San Francisco?
The U.S. State Department rates Morelos Level 3: Reconsider Travel; State of Mexico Level 2: Exercise Increased Caution; Michoacán Level 4: Do Not Travel; Jalisco Level 3: Reconsider Travel; Nayarit Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
Which highways go from Zacualpan de Amilpas to San Francisco?
In order: MEX-160, MEX-160D, MEX-95D, MEX-106, MEX-200, EM 44, MEX-55, MEX-55D, MEX-15D, MEX-15, MEX-70D and MEX-200D. The road-by-road table above shows the route miles for each one.
What are good stops between Zacualpan de Amilpas and San Francisco?
Closest to the road: Tepoztlán Ex Convento Museum (museum, mile 34, 0.5 mi from the route); Lagunas de Zempoala National Park (national park, mile 59, 0.3 mi from the route); Cathedral of Atlacomulco (cathedral, mile 134, 0.1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.