Tepic to Guadalupe, Zacatecas, Mexico Road Trip: Route & Stops

By admin, 12 October, 2026

The Wayro route from Tepic to Guadalupe, Zacatecas, Mexico is 330 miles (531 km), about 5 h 56 min of driving without stops.

U.S. State Department travel advisory: Nayarit — Level 2, Exercise Increased Caution; Jalisco — Level 3, Reconsider Travel; Aguascalientes — Level 2, Exercise Increased Caution; Zacatecas — Level 4, Do Not TravelAdvisory issued May 29, 2026; checked September 29, 2026. Zacatecas is the Mexican state that contains Guadalupe, Zacatecas. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Ixtlán del RioMuseo Interpretativo del Paisaje Agavero y la MineríaStatue of Minerva, GuadalajaraMuseo Regional de GuadalajaraParque Walt DisneyTeocaltitan Archaeological SiteCathedral Basilica of San Juan de los LagosCentro de Artes VisualesTepicGuadalupe, Zacatecas
Route from Tepic to Guadalupe, Zacatecas with the 8 stops listed below (blue dots).
Distance330 mi (531 km)
Driving time, no stops5 h 56 min
Main roads, in orderMEX-15D → MEX-15 → MEX-80D → MEX-45D → MEX-45
Mexican states on the routeNayarit, Jalisco, Aguascalientes, Zacatecas
Toll roads (as marked in OpenStreetMap)MEX-15D, MEX-80D, MEX-45D
Fuel estimate (car at 25 mpg)about 13.2 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

Driving Tepic to Guadalupe, Zacatecas: the shape of the trip

MEX-15D (125 mi) and MEX-80D (73 mi) carry about 60% of the 330 miles. It runs through 4 states: Nayarit, Jalisco, Aguascalientes, Zacatecas. OpenStreetMap marks tolled sections on MEX-15D, MEX-80D and MEX-45D. Of the 8 stops listed below, 4 are within a mile of the road.

Roads you'll take from Tepic to Guadalupe, Zacatecas

RoadRoute miles (from–to)Length, miState
local roads0–55Nayarit
MEX-15D5–110105Nayarit, Jalisco
MEX-15110–12212Jalisco
MEX-15D122–14220Jalisco
connecting roads142–1442Jalisco
MEX-80D144–21773Jalisco
local roads217–23013Jalisco
MEX-45D230–24313Jalisco
MEX-45243–27330Jalisco, Aguascalientes
local roads273–2763Aguascalientes
MEX-45276–30428Aguascalientes, Zacatecas
MEX-45D304–32521Zacatecas
local roads325–3305Zacatecas
  • Mile 62 of this route: Nayarit → Jalisco (state line)
  • Mile 247 of this route: Jalisco → Aguascalientes (state line)
  • Mile 300 of this route: Aguascalientes → Zacatecas (state line)

Where to stop on the way to Guadalupe, Zacatecas

  • Right off the route (under 1 mile): Ixtlán del Rio (mile 51), Museo Interpretativo del Paisaje Agavero y la Minería (mile 81), Statue of Minerva, Guadalajara (mile 124), Centro de Artes Visuales (mile 261)
  • Nature and outdoors: Parque Walt Disney (mile 127)
  • Museums and history: Ixtlán del Rio (mile 51), Museo Interpretativo del Paisaje Agavero y la Minería (mile 81), Museo Regional de Guadalajara (mile 126), Teocaltitan Archaeological Site (mile 204), Cathedral Basilica of San Juan de los Lagos (mile 211), Centro de Artes Visuales (mile 261)

Ixtlán del Rio

Mile 51 · Archaeological site · 0.5 mi from the route

Known locally as Los Toriles, the Ixtlán del Río site is famous for a temple with a fully circular floor plan, rare in Mesoamerica. People lived here from about 300 BC to AD 600, and an introductory gallery explains the finds.

Museo Interpretativo del Paisaje Agavero y la Minería

Mile 81 · Museum · 0.5 mi from the route

Agave landscapes and mining are the twin themes of the Museo Interpretativo del Paisaje Agavero y la Minería, an interpretive museum in the municipality of Magdalena.

Statue of Minerva, Guadalajara

Mile 124 · Statue · 0.8 mi from the route

At a roundabout fountain in Guadalajara, a bronze statue of Minerva, Roman goddess of wisdom, stands on a large pedestal inscribed with the names of 18 notable citizens.

Museo Regional de Guadalajara

Mile 126 · Museum · 2 mi from the route · side trip; actual detour depends on access roads

Facing the Rotonda de los Jaliscienses Ilustres in downtown Guadalajara, the Museo Regional de Guadalajara fills a full city block bounded by Hidalgo, Pino Suárez, Liceo and Independencia streets.

Parque Walt Disney

Mile 127 · Park · 1 mi from the route

Despite sharing a name with Walt Disney, this recreational space in Guadalajara's Colonia Olímpica has no direct theme tied to Disney's amusement parks.

Teocaltitan Archaeological Site

Mile 204 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

A people who dominated much of Los Altos between AD 400 and 900 built Teocaltitán, near Jalostotitlán. The site's pyramids, sunken patios and ball court cover about nine hectares.

Cathedral Basilica of San Juan de los Lagos

Mile 211 · Basilica · 2 mi from the route · side trip; actual detour depends on access roads

Raised between 1732 and 1769, the cathedral basilica of San Juan de los Lagos draws pilgrims from far away who come to visit the small image of the Virgin kept inside.

Centro de Artes Visuales

Mile 261 · Art museum · 0.2 mi from the route

Run by the Instituto Cultural de Aguascalientes, the Centro de Artes Visuales is an arts education center in the city of Aguascalientes with its own exhibition space for visual art.

In Guadalupe, Zacatecas itself

Museo Toma de Zacatecas

Museum · in Guadalupe, Zacatecas

On the Cerro de la Bufa, this museum explains the military and social story behind the Taking of Zacatecas during the Mexican Revolution, along with glimpses of daily life in the city at the time.

Guadalupe regional museum

Museum · in Guadalupe, Zacatecas

In Guadalupe, Zacatecas, the Museo de Guadalupe fills a former college that sent missionaries to the north and holds an important collection of 17th- to 19th-century painting, including works by Cristóbal de Villalpando, Miguel Cabrera and Juan Correa.

Cathedral Basilica of Zacatecas

Basilica · in Guadalupe, Zacatecas

Dedicated to the Virgin of the Assumption, the Cathedral of Zacatecas is the main church of the Diocese of Zacatecas.

More drives to Guadalupe, Zacatecas

From Tepic to other places in Mexico

Frequently asked questions

How long is the drive from Tepic to Guadalupe, Zacatecas, Mexico?

About 5 h 56 min of driving without stops, over 330 miles.

What is the driving distance from Tepic to Guadalupe, Zacatecas, Mexico?

About 330 miles (531 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Tepic to Guadalupe, Zacatecas?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Tepic to Guadalupe, Zacatecas?

The U.S. State Department rates Nayarit Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Aguascalientes Level 2: Exercise Increased Caution; Zacatecas Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Tepic to Guadalupe, Zacatecas?

In order: MEX-15D, MEX-15, MEX-80D, MEX-45D and MEX-45. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Tepic to Guadalupe, Zacatecas?

Closest to the road: Ixtlán del Rio (archaeological site, mile 51, 0.5 mi from the route); Museo Interpretativo del Paisaje Agavero y la Minería (museum, mile 81, 0.5 mi from the route); Centro de Artes Visuales (art museum, mile 261, 0.2 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.