São Paulo to Guarapuava is about 416 road miles (670 km): roughly 8 h 37 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Total distance | 416 mi (670 km) |
|---|---|
| Drive time without stops | 8 h 37 min |
| Main roads, in order | SP-015 → SP-280 → SP-075 → SPI 091/270 → SP-270 → SP-127 → SP-258 → PR-239 → PR-151 → PRC-373 → BR-376 → BR-373 |
| States on the route | São Paulo, Paraná |
| Fuel estimate (car at 25 mpg) | about 16.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
What the drive from São Paulo to Guarapuava is like
BR-373 (90 mi) and PR-151 (89 mi) carry about 43% of the 416 miles. It runs through 2 states: São Paulo, Paraná. Of the 8 stops listed below, 1 are within a mile of the road.
Which roads connect São Paulo and Guarapuava
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | São Paulo |
| SP-015 | 4–9 | 5 | São Paulo |
| connecting roads | 9–13 | 4 | São Paulo |
| SP-280 | 13–50 | 37 | São Paulo |
| connecting roads | 50–51 | 1 | São Paulo |
| SP-075 | 51–54 | 3 | São Paulo |
| connecting roads | 54–55 | 1 | São Paulo |
| SPI 091/270 | 55–59 | 4 | São Paulo |
| SP-270 | 59–106 | 47 | São Paulo |
| SP-127 | 106–140 | 34 | São Paulo |
| SP-258 | 140–213 | 73 | São Paulo |
| connecting roads | 213–215 | 2 | São Paulo, Paraná |
| PR-239 | 215–222 | 7 | Paraná |
| PR-151 | 222–311 | 89 | Paraná |
| PRC-373 | 311–317 | 6 | Paraná |
| BR-376 | 317–324 | 7 | Paraná |
| BR-373 | 324–414 | 90 | Paraná |
| local roads | 414–416 | 2 | Paraná |
- Mile 214 of this route: São Paulo → Paraná (state line)
What to see on the way from São Paulo to Guarapuava
- Right off the route (under 1 mile): Jaguariaíva River Canyon (mile 239)
- Nature and outdoors: Cerrado State Park (mile 235), Jaguariaíva River Canyon (mile 239), Parque Estadual Vale do Códo (mile 249), Campos Gerais National Park (mile 308)
- Museums and history: Museu de Anatomia Humana da Universidade de São Paulo (mile 10), Museu histórico e pedagógico Brigadeiro Tobias Aguiar (mile 58), Parque Histórico de Carambeí (mile 305), St. Ann Cathedral, Ponta Grossa (mile 316)
Museu de Anatomia Humana da Universidade de São Paulo
Founded by Professor Alfonso Bovero, the Museum of Human Anatomy of the University of São Paulo grew out of his teaching of anatomy and histology at the old medical school.
Museu histórico e pedagógico Brigadeiro Tobias Aguiar
Sorocaba's Brigadeiro Tobias Aguiar history museum has a permanent exhibit on the tropeiro mule-driver tradition, with paintings, furniture and everyday tropeiro objects.
Cerrado State Park
In Paraná state, Cerrado State Park protects a river canyon and the surrounding cerrado grasslands.
Jaguariaíva River Canyon
The Jaguariaíva River runs through this canyon in Jaguariaíva, in the Brazilian state of Paraná.
Parque Estadual Vale do Códo
Vale do Codó State Park lies in the municipality of Jaguariaíva, Paraná, about 230 km from Curitiba, inside the Escarpa Devoniana Environmental Protection Area.
Parque Histórico de Carambeí
Opened in 2011 for the centennial of Dutch immigration, the Carambeí Historical Park is an open-air history museum covering 100,000 square meters in Carambeí, Paraná.
Campos Gerais National Park
Created in 2006 across Ponta Grossa, Castro and Carambeí, Campos Gerais National Park protects native grasslands and Araucaria forest, with visitor sites like the Buraco do Padre sinkhole and the Mariquinha and São Jorge River waterfalls.
St. Ann Cathedral, Ponta Grossa
St. Ann Cathedral is a Catholic church in the city of Ponta Grossa, in Paraná state in southern Brazil.
Arriving in Guarapuava
Casa do Visconde de Guarapuava
In the center of Guarapuava, Paraná, the historic Casa do Visconde de Guarapuava now houses the Museu Municipal Visconde de Guarapuava.
Museu Municipal Visconde de Guarapuava
Local history is the focus at the Museu Municipal Visconde de Guarapuava, in central Guarapuava, Paraná, whose collection also includes objects used by Indigenous groups who once lived in the region.
More drives to Guarapuava
- Sorocaba to Guarapuava
- Praia Grande to Guarapuava
- São Vicente to Guarapuava
- Santos to Guarapuava
- Campinas to Guarapuava
- São José do Rio Preto to Guarapuava
From São Paulo to other places in Brazil
- São Paulo to Jundiaí
- São Paulo to Bragança Paulista
- São Paulo to Campinas
- São Paulo to Itu
- São Paulo to Mogi Guaçu
- São Paulo to São Carlos
Frequently asked questions
How long is the drive from São Paulo to Guarapuava?
About 8 h 37 min of driving without stops, over 416 miles.
How far is Guarapuava from São Paulo by car?
About 416 miles (670 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from São Paulo to Guarapuava?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from São Paulo to Guarapuava use?
In order: SP-015, SP-280, SP-075, SPI 091/270, SP-270, SP-127, SP-258, PR-239, PR-151, PRC-373, BR-376 and BR-373. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from São Paulo to Guarapuava?
Closest to the road: Museu histórico e pedagógico Brigadeiro Tobias Aguiar (museum, mile 58, 2 mi from the route); Jaguariaíva River Canyon (canyon, mile 239, 0.6 mi from the route); Parque Histórico de Carambeí (museum, mile 305, 2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.