Plan on about 9 h 46 min of driving for the 478-mile (769 km) trip from Santos to Itumbiara, before any stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Road maintenance is inadequate in many areas.”
| Distance by road | 478 mi (769 km) |
|---|---|
| Drive time without stops | 9 h 46 min |
| Main roads, in order | SP-160 → SP-015 → SP-348 → SPA-102/330 → SP-330 → SP-310 → SP-326 → BR-455 → LMG-810 → BR-262 → BR-153 |
| States on the route | São Paulo, Minas Gerais, Goiás |
| Fuel estimate (car at 25 mpg) | about 19.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
The Santos–Itumbiara drive in a few lines
SP-326 (112 mi) and BR-153 (90 mi) carry about 42% of the 478 miles. It runs through 3 states: São Paulo, Minas Gerais, Goiás. Of the 9 stops listed below, 2 are within a mile of the road.
Road-by-road breakdown: Santos to Itumbiara
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–6 | 6 | São Paulo |
| SP-160 | 6–41 | 35 | São Paulo |
| local roads | 41–47 | 6 | São Paulo |
| SP-015 | 47–55 | 8 | São Paulo |
| connecting roads | 55–56 | 1 | São Paulo |
| SP-348 | 56–106 | 50 | São Paulo |
| SPA-102/330 | 106–111 | 5 | São Paulo |
| SP-330 | 111–142 | 31 | São Paulo |
| SP-310 | 142–229 | 87 | São Paulo |
| SP-326 | 229–341 | 112 | São Paulo, Minas Gerais |
| BR-455 | 341–360 | 19 | Minas Gerais |
| local roads | 360–367 | 7 | Minas Gerais |
| LMG-810 | 367–375 | 8 | Minas Gerais |
| BR-262 | 375–383 | 8 | Minas Gerais |
| BR-153 | 383–473 | 90 | Minas Gerais |
| local roads | 473–478 | 5 | Goiás |
- Mile 340 of this route: São Paulo → Minas Gerais (state line)
- Mile 473 of this route: Minas Gerais → Goiás (state line)
Stops between Santos and Itumbiara
- Right off the route (under 1 mile): Teatro Décio de Almeida Prado (mile 47), Monument to Ramos de Azevedo (mile 51)
- Museums and history: Museu Brasileiro da Escultura (mile 48), Monument to Ramos de Azevedo (mile 51), Centro Cultural e de Estudos Superiores Aúthos Pagano (mile 55), Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão (mile 126), Memorial Casa Ronald Golias (mile 193), Our Lady of Carmel Cathedral, Jaboticabal (mile 259), André Matarazzo Museum of Arms, Vehicles and Machines Eduardo (mile 282)
Cinemateca Brasileira
The Cinemateca Brasileira is the Brazilian institution responsible for preserving the country's audiovisual production.
Teatro Décio de Almeida Prado
Teatro Décio de Almeida Prado is a theater for live performances in the city of São Paulo, Brazil.
Museu Brasileiro da Escultura
Opened in May 1995 in São Paulo's Jardim Europa, the Museu Brasileiro da Escultura e Ecologia is a private cultural institution showcasing many art forms, with a focus on sculpture and three-dimensional work.
Monument to Ramos de Azevedo
Sculptor Galileo Emendabili designed this bronze-and-granite monument in São Paulo as a tribute to architect Francisco de Paula Ramos de Azevedo.
Centro Cultural e de Estudos Superiores Aúthos Pagano
In São Paulo's Alto da Lapa neighborhood, this cultural center is a state public institution maintained by the São Paulo State Secretariat of Culture and Creative Economy together with a civil society organization.
Museu Histórico e Pedagógico Municipal Doutor João da Silva Carrão
Americana's municipal history museum occupies the old headquarters of the Fazenda Salto Grande, near where the Atibaia and Jaguari rivers meet to form the Piracicaba, and is run by the city's culture and tourism department.
Memorial Casa Ronald Golias
Opened in March 2016 in São Carlos, this memorial preserves the legacy of Ronald Golias, the nationally known comedian born in the city on May 4, 1929.
Our Lady of Carmel Cathedral, Jaboticabal
Jaboticabal's Our Lady of Carmel Cathedral stands on Joaquim Batista Square, the city's zero point. It serves as seat of the Catholic Diocese of Jaboticabal and became a parish in 1898.
André Matarazzo Museum of Arms, Vehicles and Machines Eduardo
Known locally as the Museu do Automóvel, Bebedouro's private museum grew from Eduardo André Matarazzo's collection of vintage vehicles and also shows retired airliners outdoors, including a DC-3 and a Vickers Viscount.
More drives to Itumbiara
- Limeira to Itumbiara
- Campinas to Itumbiara
- Itu to Itumbiara
- Bragança Paulista to Itumbiara
- Jundiaí to Itumbiara
- São Paulo to Itumbiara
From Santos to other places in Brazil
- Santos to Itanhaém
- Santos to Bragança Paulista
- Santos to Itu
- Santos to Limeira
- Santos to Mogi Guaçu
- Santos to Botucatu
Frequently asked questions
How long does it take to drive from Santos to Itumbiara?
About 9 h 46 min of driving without stops, over 478 miles.
How far is Itumbiara from Santos by car?
About 478 miles (769 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Santos to Itumbiara?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Santos to Itumbiara use?
In order: SP-160, SP-015, SP-348, SPA-102/330, SP-330, SP-310, SP-326, BR-455, LMG-810, BR-262 and BR-153. The road-by-road table above shows the route miles for each one.
What are good stops between Santos and Itumbiara?
Closest to the road: Teatro Décio de Almeida Prado (theater, mile 47, 0.5 mi from the route); Monument to Ramos de Azevedo (monument, mile 51, 0.7 mi from the route); Centro Cultural e de Estudos Superiores Aúthos Pagano (museum, mile 55, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.