The Wayro route from Santa Fe to La Plata is 329 miles (530 km), about 5 h 40 min of driving without stops.
Full advisory: Argentina. Advisory issued: Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
| Total distance | 329 mi (530 km) |
|---|---|
| Drive time without stops | 5 h 40 min |
| Main roads, in order | RNA007 → AP01 → RNA008 → RN9 → AV1-N → RN1 |
| Provinces on the route | Santa Fe, Buenos Aires, Ciudad de Buenos Aires |
| Fuel estimate (car at 25 mpg) | about 13.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
On the road from Santa Fe to La Plata
RN9 (170 mi) and AP01 (97 mi) carry about 81% of the 329 miles. It runs through 3 provinces: Santa Fe, Buenos Aires, Ciudad de Buenos Aires. Of the 8 stops listed below, 4 are within a mile of the road.
Santa Fe to La Plata: the road sequence
| Road | Route miles (from–to) | Length, mi | Province |
|---|---|---|---|
| local roads | 0–1 | 1 | Santa Fe |
| RNA007 | 1–6 | 5 | Santa Fe |
| AP01 | 6–103 | 97 | Santa Fe |
| RNA008 | 103–114 | 11 | Santa Fe |
| RN9 | 114–284 | 170 | Santa Fe, Buenos Aires |
| connecting roads | 284–286 | 2 | Ciudad de Buenos Aires |
| AV1-N | 286–293 | 7 | Ciudad de Buenos Aires |
| connecting roads | 293–296 | 3 | Ciudad de Buenos Aires |
| RN1 | 296–326 | 30 | Ciudad de Buenos Aires, Buenos Aires |
| local roads | 326–329 | 3 | Buenos Aires |
- Mile 145 of this route: Santa Fe → Buenos Aires (province line)
- Mile 284 of this route: Buenos Aires → Ciudad de Buenos Aires (province line)
- Mile 301 of this route: Ciudad de Buenos Aires → Buenos Aires (province line)
Where to stop on the way to La Plata
- Right off the route (under 1 mile): Parque de la Memoria (mile 288), Torre Monumental (mile 293), Ernesto de la Cárcova Museum of Reproductions and Comparative Sculpture (mile 296), Museo de la Pasión Boquense (mile 297)
- Nature and outdoors: Balneario La Florida (mile 103), Ciervo de los Pantanos National Park (mile 252), Parque de la Memoria (mile 288)
- Museums and history: Museo Histórico Cornelio de Saavedra (mile 285), Museo Nacional del Hombre (mile 288), Torre Monumental (mile 293), Ernesto de la Cárcova Museum of Reproductions and Comparative Sculpture (mile 296), Museo de la Pasión Boquense (mile 297)
Balneario La Florida
Rosario's municipal riverside beach area runs nearly 4 kilometers along the Paraná River, from the Rosario-Victoria Bridge to Parque Alem, and dates to around 1940.
Ciervo de los Pantanos National Park
Marsh deer give their name to Ciervo de los Pantanos National Park, a Ramsar Site in Campana, Buenos Aires province, where waterbirds are abundant.
Museo Histórico Cornelio de Saavedra
Inside Parque General Paz on Avenida Crisólogo Larralde, the Cornelio de Saavedra Historical Museum is a history museum of the City of Buenos Aires.
Parque de la Memoria
Facing the Río de la Plata at the northern end of Buenos Aires' Belgrano section, Parque de la Memoria is a public memorial to the victims of Argentina's 1976–1983 military regime.
Museo Nacional del Hombre
In the Belgrano district of Buenos Aires, the Museo Nacional del Hombre is a national museum focused on the archaeology of South America's Indigenous peoples.
Torre Monumental
Formerly called Torre de los Ingleses, Torre Monumental is a clock tower in the Retiro area of Buenos Aires, standing in Plaza Fuerza Aérea Argentina.
Ernesto de la Cárcova Museum of Reproductions and Comparative Sculpture
Run by the National University of Arts, this museum of reproductions and comparative sculpture is in the Puerto Madero area of Buenos Aires.
Museo de la Pasión Boquense
Football fans can dig into the history and personalities of Club Atlético Boca Juniors at the Museo de la Pasión Boquense, a themed soccer museum devoted to the club.
When you get to La Plata
Basílica de San Ponciano
On Calle 48 in La Plata, Basílica de San Ponciano is a Catholic church named a minor basilica by Pope John Paul II in 1997 and a diocesan sanctuary in 2019.
Basílica del Sagrado Corazón
The Basílica del Sagrado Corazón stands in La Plata at 58 and 9 streets and Diagonal 73, belongs to the Archdiocese of La Plata, and hosted the city's first Mass for deaf people.
Cathedral of La Plata
Facing Plaza Moreno and City Hall at the geographic center of La Plata, this neo-Gothic cathedral is dedicated to the Immaculate Conception.
More drives to La Plata
- Rosario, Argentina to La Plata
- Paraná to La Plata
- Córdoba, Argentina to La Plata
- Montevideo to La Plata, Argentina
From Santa Fe to other places in Argentina
- Santa Fe to San Nicolás de los Arroyos
- Santa Fe to Tigre
- Santa Fe to Adrogué
- Santa Fe to Berisso
- Santa Fe to Magdalena
- Santa Fe to Chascomús
Frequently asked questions
How long is the drive from Santa Fe to La Plata?
About 5 h 40 min of driving without stops, over 329 miles.
What is the driving distance from Santa Fe to La Plata?
About 329 miles (530 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Santa Fe to La Plata?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
What roads does the drive from Santa Fe to La Plata use?
In order: RNA007, AP01, RNA008, RN9, AV1-N and RN1. The road-by-road table above shows the route miles for each one.
What are good stops between Santa Fe and La Plata?
Closest to the road: Parque de la Memoria (memorial park, mile 288, 0.5 mi from the route); Torre Monumental (monument, mile 293, 0.5 mi from the route); Ernesto de la Cárcova Museum of Reproductions and Comparative Sculpture (art museum, mile 296, 0.6 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.