The Wayro route from Santa Cruz, Chile to Malargüe, Argentina is 260 miles (419 km), about 6 h 10 min of driving without stops. You cross from Chile into Argentina at about mile 173, at Paso Pehuenche.
Full advisory: Chile, Argentina. Advisory issued: Chile August 19, 2026; Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Chile: “Secondary and mountain roads may be poorly maintained, poorly lit, and may lack guardrails.”
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
| Total distance | 260 mi (419 km) |
|---|---|
| Driving time, no stops | 6 h 10 min |
| Main roads, in order | I-86 → I-300-J → J-300-I → J-40 → RN145 → RN40 |
| Border crossing | about mile 173, Chile → Argentina (Paso Pehuenche) |
| Regions on the route | Libertador General Bernardo O'Higgins, Maule, Mendoza |
| Fuel estimate (car at 25 mpg) | about 10.4 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
Crossing from Chile into Argentina
The route crosses at about mile 173, at Paso Pehuenche, from Maule into Mendoza. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
|---|---|
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Entering Chile (U.S. citizens) | No visa needed for 90 days or less on a tourist passport; you get a Tourist Card valid for up to 90 days. Passport: must be valid for your whole stay. |
| Driving in Chile | A valid U.S. license works for the length of your tourist permit, usually 90 days. |
| The car, entering Argentina | Argentine customs (ARCA) registers the car's temporary entry. Bring the title or registration, liability insurance valid in Argentina and, if you don't own the car, a power of attorney signed before a notary. A rental car needs the rental company's MERCOSUR circulation authorization (ACM), and the company must be registered with Argentine customs. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Argentina (updated July 16, 2026); U.S. State Department, Chile (updated July 02, 2026); ARCA (Argentine customs). Checked October 10, 2026; rules change, so confirm before you go.
The Santa Cruz–Malargüe drive in a few lines
RN145 (46 mi) and RN40 (41 mi) carry about 33% of the 260 miles. The first 173 miles are in Chile; the last 87 are in Argentina. It runs through 3 regions: Libertador General Bernardo O'Higgins, Maule, Mendoza. Of the 4 stops listed below, 1 are within a mile of the road.
Roads you'll take from Santa Cruz to Malargüe
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–1 | 1 | Libertador General Bernardo O'Higgins |
| I-86 | 1–13 | 12 | Libertador General Bernardo O'Higgins |
| I-300-J | 13–19 | 6 | Libertador General Bernardo O'Higgins |
| J-300-I | 19–22 | 3 | Libertador General Bernardo O'Higgins, Maule |
| J-40 | 22–26 | 4 | Maule |
| local roads | 26–173 | 147 | Maule |
| RN145 | 173–219 | 46 | Mendoza |
| RN40 | 219–260 | 41 | Mendoza |
- Mile 20 of this route: Libertador General Bernardo O'Higgins → Maule (region line)
- Mile 173 of this route: Maule → Mendoza (international border)
Where to stop on the way to Malargüe
- Right off the route (under 1 mile): Teatro Victoria (mile 35)
- Nature and outdoors: Campanario Thermal Baths (mile 153), Médanos Grandes (mile 221)
- Museums and history: St. Augustine Cathedral, Talca (mile 74)
Teatro Victoria
St. Augustine Cathedral, Talca
Also known as Talca Cathedral, St. Augustine Cathedral is a Catholic cathedral in Talca, Chile, dedicated to Saint Augustine.
Campanario Thermal Baths
Campanario Thermal Baths (Baños Campanario) are hot springs in Chile's Maule Region, used both for medicinal purposes and by visitors looking for a soak.
Médanos Grandes
Médanos Grandes is a dune field in west-central Argentina, a sandy landscape that covers an area of roughly 2,000 square kilometers.
More drives to Malargüe
- Villa Carlos Paz to Malargüe
- Santiago, Chile to Malargüe, Argentina
- Valparaíso to Malargüe, Argentina
- Temuco to Malargüe, Argentina
- Rancagua to Malargüe, Argentina
- Concepción, Chile to Malargüe, Argentina
More drives from Santa Cruz
- Santa Cruz, Chile to Valle Nevado
- Santa Cruz, Chile to Vicuña
- Santa Cruz, Chile to Pisco Elqui
- Santa Cruz, Chile to Punta de Choros
- Santa Cruz, Chile to La Punta, Argentina
- Santa Cruz, Chile to San José de Jáchal, Argentina
Frequently asked questions
How long is the drive from Santa Cruz, Chile to Malargüe, Argentina?
About 6 h 10 min of driving without stops, over 260 miles.
What is the driving distance from Santa Cruz, Chile to Malargüe, Argentina?
About 260 miles (419 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Santa Cruz to Malargüe drive cross the border?
At about mile 173, from Chile into Argentina, at Paso Pehuenche.
What do U.S. citizens need to drive from Santa Cruz into Argentina?
No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. A valid U.S. license usually works; an International Driving Permit is recommended. (U.S. State Department, updated July 16, 2026.)
What does the U.S. travel advisory say about the Santa Cruz to Malargüe drive?
The U.S. State Department rates Chile Level 2: Exercise Increased Caution; Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
Which highways go from Santa Cruz to Malargüe?
In order: I-86, I-300-J, J-300-I, J-40, RN145 and RN40. The road-by-road table above shows the route miles for each one.
What are good stops between Santa Cruz and Malargüe?
Closest to the road: Teatro Victoria (theater, mile 35, 0.8 mi from the route); St. Augustine Cathedral, Talca (cathedral, mile 74, 2 mi from the route); Campanario Thermal Baths (hot spring, mile 153, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.