The Wayro route from San Andrés Tuxtla to Calpulalpan is 296 miles (476 km), about 5 h 2 min of driving without stops.
| Distance | 296 mi (476 km) |
|---|---|
| Driving time, no stops | 5 h 2 min |
| Main roads, in order | MEX-179 → MEX-145D → MEX-150D → MEX-M40D → MEX-136 |
| Mexican states on the route | Veracruz (Level 2), Puebla (Level 2), Tlaxcala (Level 2) |
| Toll roads | MEX-145D, MEX-150D, MEX-M40D |
| Fuel estimate (car at 25 mpg) | about 11.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from San Andrés Tuxtla to Calpulalpan is like
MEX-150D (157 mi) and MEX-145D (74 mi) carry about 78% of the 296 miles. MEX-145D, MEX-150D, MEX-M40D are toll highways (cuota); MEX-179, MEX-136 are free federal roads (libre). It runs through 3 states: Veracruz, Puebla, Tlaxcala. Of the 8 stops listed below, 1 are within a mile of the road.
The route from San Andrés Tuxtla to Calpulalpan, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–15 | 15 | Veracruz |
| MEX-179 | 15–35 | 20 | Veracruz |
| connecting roads | 35–36 | 1 | Veracruz |
| MEX-145D | 36–110 | 74 | Veracruz |
| MEX-150D | 110–267 | 157 | Veracruz, Puebla |
| connecting roads | 267–268 | 1 | Puebla |
| MEX-M40D | 268–286 | 18 | Puebla, Tlaxcala |
| MEX-136 | 286–295 | 9 | Tlaxcala |
| local roads | 295–296 | 1 | Tlaxcala |
- Mile 179 of this route: Veracruz → Puebla (state line)
- Mile 272 of this route: Puebla → Tlaxcala (state line)
Stops between San Andrés Tuxtla and Calpulalpan
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 165)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 165), La Malinche National Park (mile 240), Parque nacional Xicoténcatl (mile 261)
- Museums and history: Huatusco (mile 117), Orizaba Cathedral (mile 157), Casa del Mendrugo (mile 248), Xochitecatl (mile 263)
Huatusco
Above the Atoyac River in Carrillo Puerto, the ruins of Huatusco (Cuauhtochco) include a Mexica-era temple that still keeps original surface finishes. There are no visitor facilities; reaching it means crossing a suspension bridge and climbing a steep trail, ideally with a local guide.
Orizaba Cathedral
The Cathedral of St. Michael the Archangel is the main Catholic church of Orizaba, in the state of Veracruz, and the seat of the Diocese of Orizaba.
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
La Malinche National Park
Tlaxcala's La Malinche National Park surrounds the inactive Matlalcuéyetl volcano, with pine, oak and fir forests on its slopes, hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center.
Teatro Principal
The Teatro Principal is a historic theater in the city of Puebla that is still active as a stage for performances.
Casa del Mendrugo
Dating back to the early years of Puebla, founded in 1531, the Casa del Mendrugo is a historic house at 4 Sur 304 in the city's historic center.
Parque nacional Xicoténcatl
Covering roughly 600 hectares in central Tlaxcala, Xicohténcatl National Park takes in the historic center of Tlaxcala city plus Quiahuixtlán, Ocotelulco and Tepeticpac, which correspond to three of the old Tlaxcalan lordships.
Xochitecatl
Xochitécatl is a pre-Hispanic archaeological site in the state of Tlaxcala. INAH runs it together with nearby Cacaxtla as a single zone, and the Xochitécatl site museum displays finds from the area.
When you get to Calpulalpan
Tecoaque
Near Calpulalpan in western Tlaxcala, Tecoaque is a Mesoamerican archaeological site once inhabited by the Acolhua, one of the three groups that made up the Aztec Empire.
More drives to Calpulalpan
- Mexico City to Calpulalpan
- Pachuca to Calpulalpan
- Tepotzotlán to Calpulalpan
- Toluca to Calpulalpan
- Cuautla to Calpulalpan
- Cuernavaca to Calpulalpan
From San Andrés Tuxtla to other places in Mexico
- San Andrés Tuxtla to Zacatelco
- San Andrés Tuxtla to Chiautempan
- San Andrés Tuxtla to Huejotzingo
- San Andrés Tuxtla to Tlaxco
- San Andrés Tuxtla to Ocuituco
- San Andrés Tuxtla to Zacatlán
Continue Your Adventure
Frequently asked questions
How long is the drive from San Andrés Tuxtla to Calpulalpan?
About 5 h 2 min of driving without stops, over 296 miles.
How far is Calpulalpan from San Andrés Tuxtla by car?
About 296 miles (476 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from San Andrés Tuxtla to Calpulalpan?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from San Andrés Tuxtla to Calpulalpan?
The U.S. State Department rates Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from San Andrés Tuxtla to Calpulalpan use?
In order: MEX-179, MEX-145D, MEX-150D, MEX-M40D and MEX-136. The road-by-road table above shows the route miles and states for each one.
What are good stops between San Andrés Tuxtla and Calpulalpan?
Closest to the road: Orizaba Cathedral (cathedral, mile 157, 1 mi from the route); Cañón del Río Blanco National Park (National Park of Mexico, mile 165, 0.5 mi from the route); Xochitecatl (archaeological site, mile 263, 2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.