Salamanca to Tlaltizapán Road Trip: Route, Stops & Safety

By admin, 3 October, 2026

The Wayro route from Salamanca to Tlaltizapán is 255 miles (411 km), about 4 h 39 min of driving without stops.

U.S. State Department travel advisory: Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Mexico City — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Tlaltizapán. Check the full advisory for this state before you go.
Celaya CathedralCerro de las CampanasTlalnepantla CathedralMuseo Universitario del ChopoMonumento a la Madre, Mexico CityLeon Trotsky House MuseumMuseo Casa Estudio Diego Rivera y Frida KahloAnahuacalli MuseumPalace of Cortés, CuernavacaSalamancaTlaltizapán
Route from Salamanca to Tlaltizapán with the 9 stops listed below (blue dots).
Distance255 mi (411 km)
Driving time, no stops4 h 39 min
Main roads, in orderMEX-45D → MEX-47D → MEX-57D → MEX-57 → Periférico → MEX-95D → MEX-95 → MOR 14
Mexican states on the routeGuanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Mexico City (Level 2), Morelos (Level 3)
Toll roadsMEX-45D, MEX-47D, MEX-57D, MEX-95D
Fuel estimate (car at 25 mpg)about 10.2 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Salamanca to Tlaltizapán is like

MEX-57D (74 mi) and MEX-47D (52 mi) carry about 49% of the 255 miles. MEX-45D, MEX-47D, MEX-57D, MEX-95D are toll highways (cuota); MEX-57, MEX-95 are free federal roads (libre). It runs through 6 states: Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos. Of the 9 stops listed below, 1 are within a mile of the road.

The route from Salamanca to Tlaltizapán, road by road

RoadRoute miles (from–to)Length, miState
local roads0–22Guanajuato
MEX-45D2–3937Guanajuato
MEX-47D39–9152Guanajuato, Querétaro
MEX-57D91–16574Querétaro, State of Mexico, Hidalgo
MEX-57165–1738State of Mexico
Periférico173–19320State of Mexico, Mexico City
connecting roads193–1941Mexico City
MEX-95D194–21622Mexico City, Morelos
connecting roads216–22610Morelos
MEX-95226–2348Morelos
MEX-95D234–2428Morelos
connecting roads242–2442Morelos
MOR 14244–2506Morelos
local roads250–2555Morelos
  • Mile 52 of this route: Guanajuato → Querétaro (state line)
  • Mile 93 of this route: Querétaro → State of Mexico (state line)
  • Mile 126 of this route: State of Mexico → Hidalgo (state line)
  • Mile 146 of this route: Hidalgo → State of Mexico (state line)
  • Mile 178 of this route: State of Mexico → Mexico City (state line)
  • Mile 211 of this route: Mexico City → Morelos (state line)

Stops between Salamanca and Tlaltizapán

  • Right off the route (under 1 mile): Museo Casa Estudio Diego Rivera y Frida Kahlo (mile 185)
  • Nature and outdoors: Cerro de las Campanas (mile 50)
  • Museums and history: Celaya Cathedral (mile 27), Tlalnepantla Cathedral (mile 169), Museo Universitario del Chopo (mile 180), Monumento a la Madre, Mexico City (mile 180), Leon Trotsky House Museum (mile 183), Museo Casa Estudio Diego Rivera y Frida Kahlo (mile 185), Anahuacalli Museum (mile 192), Palace of Cortés, Cuernavaca (mile 234)

Celaya Cathedral

Mile 27 · Church building · 2 mi from the route · side trip; actual detour depends on access roads

Celaya's main Catholic church, the Immaculate Conception Cathedral, occupies the space of a former chapel that was annexed to the neighboring Temple of St. Francis.

Cerro de las Campanas

Mile 50 · National Park of Mexico · 12 mi from the route · side trip; actual detour depends on access roads

Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.

Tlalnepantla Cathedral

Mile 169 · Catholic cathedral · 1 mi from the route

Consecrated on August 23, 1964, Tlalnepantla's Corpus Christi Cathedral stands where Franciscans founded the Convent of San Francisco in 1525.

Museo Universitario del Chopo

Mile 180 · Art museum · 3 mi from the route · side trip; actual detour depends on access roads

In the Santa María la Ribera neighborhood, the Museo Universitario del Chopo is the National Autonomous University's venue for contemporary art collections.

Monumento a la Madre, Mexico City

Mile 180 · Monument · 2 mi from the route · side trip; actual detour depends on access roads

Inaugurated on May 10, 1949, the Monumento a la Madre in Mexico City is a monument honoring and commemorating Mexican mothers.

Leon Trotsky House Museum

Mile 183 · Historic house museum · 2 mi from the route · side trip; actual detour depends on access roads

In Coyoacán, the house museum honoring Leon Trotsky, officially the Instituto del Derecho de Asilo - Museo Casa de León Trotsky, also works to promote political asylum.

Museo Casa Estudio Diego Rivera y Frida Kahlo

Mile 185 · Museum · 0.3 mi from the route

Juan O'Gorman designed these two functionalist houses in 1931 for Diego Rivera and Frida Kahlo, one red and white, one blue, joined by a small rooftop bridge. Since 1986 they've been a museum about the couple and their generation.

Anahuacalli Museum

Mile 192 · Museum · 2 mi from the route

Designed by muralist Diego Rivera as a temple of the arts, the Anahuacalli Museum is a museum and arts center in the San Pablo de Tepetlapa neighborhood of Coyoacán.

Palace of Cortés, Cuernavaca

Mile 234 · Fortified palace · 2 mi from the route

Begun in the 16th century, the Palace of Cortés in Cuernavaca now holds the Museo Regional de los Pueblos de Morelos, reopened in 2023. Out on the east terrace, Diego Rivera's mural on the history of Morelos is back on view.

More drives to Tlaltizapán

From Salamanca to other places in Mexico

Frequently asked questions

How long is the drive from Salamanca to Tlaltizapán?

About 4 h 39 min of driving without stops, over 255 miles.

How far is Tlaltizapán from Salamanca by car?

About 255 miles (411 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Salamanca to Tlaltizapán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Salamanca to Tlaltizapán?

The U.S. State Department rates Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Mexico City Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Salamanca to Tlaltizapán use?

In order: MEX-45D, MEX-47D, MEX-57D, MEX-57, Periférico, MEX-95D, MEX-95 and MOR 14. The road-by-road table above shows the route miles and states for each one.

What are good stops between Salamanca and Tlaltizapán?

Closest to the road: Tlalnepantla Cathedral (catholic cathedral, mile 169, 1 mi from the route); Museo Casa Estudio Diego Rivera y Frida Kahlo (museum, mile 185, 0.3 mi from the route); Palace of Cortés, Cuernavaca (fortified palace, mile 234, 2 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.