The Wayro route from Resistencia to Salto, Uruguay is 333 miles (536 km), about 6 h 46 min of driving without stops. You cross from Argentina into Uruguay at about mile 324, at Concordia–Salto.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers should prepare in advance when taking long road trips and make sure to have adequate insurance coverage.”
- Uruguay: “If you are in an accident involving injury, stay in place until a police officer arrives.”
| Total distance | 333 mi (536 km) |
|---|---|
| Time at the wheel, no stops | 6 h 46 min |
| Main roads, in order | RP63 → RN16 → RN12 → RN123 → RN119 → RN14 → RNA015 |
| Border crossing | about mile 324, Argentina → Uruguay (Concordia–Salto) |
| Regions on the route | Chaco, Corrientes, Entre Ríos, Salto |
| Fuel estimate (car at 25 mpg) | about 13.3 gal; actual use varies by vehicle and traffic |
| Stops listed below | 3 |
The border on the way to Salto
The route crosses at about mile 324, at Concordia–Salto, from Entre Ríos into Salto. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
On the road from Resistencia to Salto
RN12 (98 mi) and RN14 (85 mi) carry about 55% of the 333 miles. The first 324 miles are in Argentina; the last 9 are in Uruguay. It runs through 4 regions: Chaco, Corrientes, Entre Ríos, Salto. Of the 3 stops listed below, 2 are within a mile of the road.
Road-by-road breakdown: Resistencia to Salto
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–4 | 4 | Chaco |
| RP63 | 4–8 | 4 | Chaco |
| RN16 | 8–11 | 3 | Chaco |
| local roads | 11–16 | 5 | Corrientes |
| RN12 | 16–114 | 98 | Corrientes |
| RN123 | 114–160 | 46 | Corrientes |
| RN119 | 160–227 | 67 | Corrientes |
| connecting roads | 227–228 | 1 | Corrientes |
| RN14 | 228–313 | 85 | Corrientes, Entre Ríos |
| RNA015 | 313–324 | 11 | Entre Ríos |
| local roads | 324–333 | 9 | Salto |
- Mile 11 of this route: Chaco → Corrientes (region line)
- Mile 265 of this route: Corrientes → Entre Ríos (region line)
- Mile 324 of this route: Entre Ríos → Salto (international border)
Breaking up the drive: stops between Resistencia and Salto
- Right off the route (under 1 mile): Corrientes Cathedral (mile 12), Termas de Salto Grande (mile 324)
- Nature and outdoors: Iberá National Park (mile 73), Termas de Salto Grande (mile 324)
- Museums and history: Corrientes Cathedral (mile 12)
Corrientes Cathedral
Corrientes Cathedral, dedicated to Our Lady of the Rosary, is a Roman Catholic church in the city of Corrientes and part of the Archdiocese of Corrientes.
Iberá National Park
In the northeastern province of Corrientes, Iberá National Park borders the 5,530 square-kilometer Iberá Provincial Park to the southeast.
Termas de Salto Grande
On the Uruguayan shore of the Salto Grande dam's lake in Salto department, Termas de Salto Grande is a hot spring complex.
Once you reach Salto
Museo del Centro Cultural Casa Horacio Quiroga
In Salto, the Museo del Centro Cultural Casa Horacio Quiroga (Casa Quiroga) tells the life and work of writer Horacio Quiroga inside a house that was one of his family's summer homes.
Museo del Hombre y la Tecnología
In Uruguay's Salto department, the Museo del Hombre y la Tecnología shows how changing technology has shaped daily life in Uruguay and elsewhere.
Teatro Larrañaga
Teatro Larrañaga is the main performing arts venue in the city of Salto, Uruguay.
More drives to Salto
- Montevideo to Salto
- Buenos Aires to Salto, Uruguay
- Córdoba, Argentina to Salto, Uruguay
- Rosario, Argentina to Salto, Uruguay
- Mar del Plata to Salto, Uruguay
- Santa Fe to Salto, Uruguay
More drives from Resistencia
- Resistencia to Mercedes, Argentina
- Resistencia to Paso de los Libres
- Resistencia to Paraná
- Resistencia to Colón, Argentina
- Resistencia to San Nicolás de los Arroyos
- Resistencia to Pergamino
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Resistencia to Salto, Uruguay?
About 6 h 46 min of driving without stops, over 333 miles.
How far is Salto, Uruguay from Resistencia by car?
About 333 miles (536 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Resistencia to Salto drive cross the border?
At about mile 324, from Argentina into Uruguay, at Concordia–Salto.
What do U.S. citizens need to drive from Resistencia into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from Resistencia to Salto, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Resistencia to Salto use?
In order: RP63, RN16, RN12, RN123, RN119, RN14 and RNA015. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Resistencia to Salto?
Closest to the road: Corrientes Cathedral (cathedral, mile 12, 0.5 mi from the route); Iberá National Park (national park, mile 73, 5 mi from the route); Termas de Salto Grande (hot spring, mile 324, 0.8 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.