Plan on about 11 h 54 min of driving for the 466-mile (750 km) trip from Quillacollo to San José de Chiquitos, before any stops.
- Level 4: Do Not Travel in Bolivia: Chapare Province.
This route passes through or near an area the State Department rates Do Not Travel. Read the full advisory before you plan this drive: Bolivia. Advisory issued: Bolivia August 18, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Bolivia: “Most highways do not have shoulders, fences, or barriers, and there are few lane markings.”
| Total distance | 466 mi (750 km) |
|---|---|
| Time at the wheel, no stops | 11 h 54 min |
| Main roads, in order | F4 |
| Departments on the route | Cochabamba, Santa Cruz |
| Fuel estimate (car at 25 mpg) | about 18.6 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
Driving Quillacollo to San José de Chiquitos: the shape of the trip
F4 (445 mi) carries about 95% of the 466 miles. It runs through 2 departments: Cochabamba, Santa Cruz. Of the 4 stops listed below, 2 are within a mile of the road.
Quillacollo to San José de Chiquitos: the road sequence
| Road | Route miles (from–to) | Length, mi | Department |
|---|---|---|---|
| F4 | 0–170 | 170 | Cochabamba |
| local roads | 170–174 | 4 | Cochabamba |
| F4 | 174–218 | 44 | Cochabamba, Santa Cruz |
| local roads | 218–221 | 3 | Santa Cruz |
| F4 | 221–292 | 71 | Santa Cruz |
| local roads | 292–302 | 10 | Santa Cruz |
| F4 | 302–462 | 160 | Santa Cruz |
| local roads | 462–466 | 4 | Santa Cruz |
- Mile 189 of this route: Cochabamba → Santa Cruz (department line)
What to see on the way from Quillacollo to San José de Chiquitos
- Right off the route (under 1 mile): Metropolitan Cathedral of Saint Sebastian (mile 8), Jardín Botánico de Santa Cruz de la Sierra (mile 303)
- Nature and outdoors: Piraí River Ecological Protection Park (mile 297), Jardín Botánico de Santa Cruz de la Sierra (mile 303)
- Museums and history: Metropolitan Cathedral of Saint Sebastian (mile 8), Inkachaka (mile 61)
Metropolitan Cathedral of Saint Sebastian
Standing on Plaza 14 de Septiembre in Cochabamba, the Metropolitan Cathedral of Saint Sebastian is the cathedral of the Archdiocese of Cochabamba.
Inkachaka
Inkachaka (Inka Chaka) is an archaeological site in Bolivia's Cochabamba Department, within the Colomi Municipality of Chapare Province.
Piraí River Ecological Protection Park
Along the banks of the Piraí River, this protected park preserves natural areas and helps shield Santa Cruz de la Sierra from river floods.
Jardín Botánico de Santa Cruz de la Sierra
The municipal botanical garden of Santa Cruz de la Sierra covers 217 hectares within the city.
In San José de Chiquitos itself
Parque nacional Histórico Santa Cruz La Vieja
About 3 km south of San José de Chiquitos, Santa Cruz la Vieja is a historic national park protecting archaeological, historical, and natural features.
More drives to San José de Chiquitos
- Cochabamba to San José de Chiquitos
- Sucre to San José de Chiquitos
- Campo Grande to San José de Chiquitos, Bolivia
From Quillacollo to other places in Bolivia
- Quillacollo to Llallagua
- Quillacollo to Challapata
- Quillacollo to Tiwanaku
- Quillacollo to Coroico
- Quillacollo to Chulumani
- Quillacollo to San Borja
Continue Your Adventure
Frequently asked questions
How long is the drive from Quillacollo to San José de Chiquitos?
About 11 h 54 min of driving without stops, over 466 miles.
How far is San José de Chiquitos from Quillacollo by car?
About 466 miles (750 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Quillacollo to San José de Chiquitos drive?
The U.S. State Department rates Bolivia Level 2: Exercise Increased Caution. Parts of this route are in or near areas rated Level 4: Do Not Travel (Bolivia: Chapare Province). Read the full advisory before you go.
What are good stops between Quillacollo and San José de Chiquitos?
Closest to the road: Metropolitan Cathedral of Saint Sebastian (cathedral, mile 8, 0.2 mi from the route); Inkachaka (archaeological site, mile 61, 2 mi from the route); Jardín Botánico de Santa Cruz de la Sierra (botanical garden, mile 303, 0.4 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.