Puerto López to Guano is about 269 road miles (433 km): roughly 6 h 17 min at the wheel if you don't stop.
- Level 4: Do Not Travel in Ecuador: Duran, in Guayas province.
- Level 4: Do Not Travel in Ecuador: In Guayaquil: Nueva Prosperina and Pascuales districts, and all areas south of Portete de Tarqui Avenue (areas north of the avenue are Level 3).
- Level 3: Reconsider Travel in Ecuador: Sucumbios, Manabi, Santa Elena, and Santo Domingo provinces.
This route passes through or near an area the State Department rates Do Not Travel. Read the full advisory before you plan this drive: Ecuador. Advisory issued: Ecuador August 18, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Ecuador: “Heavy fog and rain make conditions more dangerous.”
| Distance | 269 mi (433 km) |
|---|---|
| Driving time, no stops | 6 h 17 min |
| Main roads, in order | E15 → E483 → E482 → E48 → E40 → E487 → E35 |
| Provinces on the route | Manabi, Guayas, Cañar, Chimborazo |
| Fuel estimate (car at 25 mpg) | about 10.8 gal; actual use varies by vehicle and traffic |
| Stops listed below | 4 |
The Puerto López–Guano drive in a few lines
E487 (87 mi) and E482 (63 mi) carry about 56% of the 269 miles. It runs through 4 provinces: Manabi, Guayas, Cañar, Chimborazo. Of the 4 stops listed below, 1 are within a mile of the road.
Which roads connect Puerto López and Guano
| Road | Route miles (from–to) | Length, mi | Province |
|---|---|---|---|
| E15 | 0–20 | 20 | Manabi |
| E483 | 20–35 | 15 | Manabi |
| E482 | 35–98 | 63 | Manabi, Guayas |
| E48 | 98–112 | 14 | Guayas |
| connecting roads | 112–114 | 2 | Guayas |
| local roads | 114–123 | 9 | Guayas |
| E40 | 123–159 | 36 | Guayas |
| local roads | 159–163 | 4 | Guayas, Cañar |
| E487 | 163–250 | 87 | Cañar, Guayas, Chimborazo |
| connecting roads | 250–252 | 2 | Chimborazo |
| E35 | 252–257 | 5 | Chimborazo |
| local roads | 257–269 | 12 | Chimborazo |
- Mile 70 of this route: Manabi → Guayas (province line)
- Mile 160 of this route: Guayas → Cañar (province line)
- Mile 176 of this route: Cañar → Guayas (province line)
- Mile 185 of this route: Guayas → Chimborazo (province line)
Places worth a stop between Puerto López and Guano
- Right off the route (under 1 mile): Jardín Botánico de Guayaquil (mile 115)
- Nature and outdoors: Jardín Botánico de Guayaquil (mile 115), Laguna de Colta (mile 247)
- Museums and history: Guayaquil Metropolitan Cathedral (mile 123), Museo Municipal de música popular Julio Jaramillo (mile 124)
Jardín Botánico de Guayaquil
Living plant collections grown for conservation, research and education fill the Jardín Botánico de Guayaquil, a 5-hectare botanical garden in Guayaquil, Ecuador.
Guayaquil Metropolitan Cathedral
In the center of Guayaquil, the Metropolitan Cathedral succeeds the church that served as the city's main cathedral when Guayaquil was founded.
Museo Municipal de música popular Julio Jaramillo
Named for singer Julio Jaramillo, this municipal museum in Guayaquil opened in 2008 and displays objects tracing Ecuadorian popular music from 1892 to 1978.
Laguna de Colta
Laguna de Colta is a lake of about 275 hectares in Colta canton, Chimborazo province, in Ecuador's central highlands, home to native birds and many kinds of colorful fish.
More drives to Guano
- Otavalo to Guano
- Ibarra to Guano
- Salinas to Guano
- Pasto to Guano, Ecuador
- Popayán to Guano, Ecuador
- Ipiales to Guano, Ecuador
From Puerto López to other places in Ecuador
Frequently asked questions
How long does it take to drive from Puerto López to Guano?
About 6 h 17 min of driving without stops, over 269 miles.
What is the driving distance from Puerto López to Guano?
About 269 miles (433 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Puerto López to Guano?
The U.S. State Department rates Ecuador Level 2: Exercise Increased Caution. Parts of this route are in or near areas rated Level 4: Do Not Travel (Ecuador: Duran, in Guayas province; Ecuador: In Guayaquil: Nueva Prosperina and Pascuales districts, and all areas south of Portete de Tarqui Avenue (areas north of the avenue are Level 3)). Read the full advisory before you go.
Which highways go from Puerto López to Guano?
In order: E15, E483, E482, E48, E40, E487 and E35. The road-by-road table above shows the route miles for each one.
What are good stops between Puerto López and Guano?
Closest to the road: Jardín Botánico de Guayaquil (botanical garden, mile 115, 0.8 mi from the route); Museo Municipal de música popular Julio Jaramillo (museum, mile 124, 2 mi from the route); Laguna de Colta (lagoon, mile 247, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.