The Wayro route from Popayán to Quevedo, Ecuador is 523 miles (842 km), about 14 h 17 min of driving without stops. You cross from Colombia into Ecuador at about mile 215.
- Level 4: Do Not Travel in Colombia: Cauca (excluding Popayán).
- Level 4: Do Not Travel in Ecuador: Quevedo, Quinsaloma, and Pueblo Viejo, in Los Rios province.
- Level 3: Reconsider Travel in Ecuador: Los Rios province, outside Quevedo, Quinsaloma, and Pueblo Viejo.
- Level 3: Reconsider Travel in Ecuador: Sucumbios, Manabi, Santa Elena, and Santo Domingo provinces.
This route passes through or near an area the State Department rates Do Not Travel. Read the full advisory before you plan this drive: Colombia, Ecuador. Advisory issued: Colombia March 31, 2026; Ecuador August 18, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Colombia: “Travel only during daylight hours.”
- Ecuador: “Some roads are poorly maintained. They may lack crash barriers, guard rails, signs, and streetlights.”
| Distance | 523 mi (842 km) |
|---|---|
| Drive time without stops | 14 h 17 min |
| Main roads, in order | 25 NR C → E35 → E282 → E28B → E28 → E25 |
| Border crossing | about mile 215, Colombia → Ecuador |
| Regions on the route | Cauca, Nariño, Carchi, Imbabura, Pichincha, Santo Domingo de los Tsáchilas, Los Rios |
| Fuel estimate (car at 25 mpg) | about 20.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 6 |
Getting across the Colombia–Ecuador border
The route crosses at about mile 215, from Nariño into Carchi. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Ecuador (U.S. citizens) | No visa needed unless you stay more than 90 days in any 12-month period. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Ecuador | A valid U.S. license is recognized for up to 90 days. |
| Entering Colombia (U.S. citizens) | No visa needed for 90 days or less. Passport: must be valid for your whole stay (6 months recommended), with a blank page for the entry stamp. |
| The car, entering Ecuador | You must pay for Ecuador's local liability insurance, called SPPAT. For the car's temporary entry, check with Ecuador's National Customs Service. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Ecuador (updated February 18, 2026); U.S. State Department, Colombia (updated August 11, 2025). Checked October 10, 2026; rules change, so confirm before you go.
What the drive from Popayán to Quevedo is like
E35 (107 mi) and E25 (103 mi) carry about 40% of the 523 miles. The first 215 miles are in Colombia; the last 308 are in Ecuador. It runs through 7 regions: Cauca, Nariño, Carchi, Imbabura, Pichincha, Santo Domingo de los Tsáchilas, Los Rios. Of the 6 stops listed below, 1 are within a mile of the road.
The route from Popayán to Quevedo, road by road
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–209 | 209 | Cauca, Nariño |
| 25 NR C | 209–213 | 4 | Nariño |
| connecting roads | 213–214 | 1 | Nariño |
| E35 | 214–321 | 107 | Nariño, Carchi, Imbabura |
| E282 | 321–327 | 6 | Pichincha |
| E28B | 327–357 | 30 | Pichincha |
| local roads | 357–365 | 8 | Pichincha |
| E28 | 365–418 | 53 | Pichincha |
| connecting roads | 418–419 | 1 | Pichincha |
| E25 | 419–522 | 103 | Pichincha, Santo Domingo de los Tsáchilas, Los Rios |
| local roads | 522–523 | 1 | Los Rios |
- Mile 94 of this route: Cauca → Nariño (region line)
- Mile 215 of this route: Nariño → Carchi (international border)
- Mile 267 of this route: Carchi → Imbabura (region line)
- Mile 321 of this route: Imbabura → Pichincha (region line)
- Mile 431 of this route: Pichincha → Santo Domingo de los Tsáchilas (region line)
- Mile 485 of this route: Santo Domingo de los Tsáchilas → Los Rios (region line)
Stops between Popayán and Quevedo
- Right off the route (under 1 mile): Ciudad Mitad del Mundo (mile 366)
- Nature and outdoors: Ciudad Mitad del Mundo (mile 366), Pululahua Geobotanical Reserve (mile 368), Jardín botánico La Carolina (mile 457)
- Museums and history: St. Ezequiel Moreno Cathedral, Pasto (mile 155), Sanctuary of Las Lajas (mile 209), Cochasquí (mile 334)
St. Ezequiel Moreno Cathedral, Pasto
Pasto Cathedral is the mother church of the Diocese of Pasto and takes its name from St. Ezequiel Moreno, the friar who was appointed the city's bishop in 1895.
Sanctuary of Las Lajas
Built between 1916 and 1949 inside the Guáitara River canyon near Ipiales, the neo-Gothic Sanctuary of Las Lajas is reached by a bridge about 50 meters long. The Marian shrine also has a museum and a crypt.
Cochasquí
On the slopes of Mojanda, an inactive volcano in Pichincha province, Cochasquí is an archaeological site in Ecuador's northern highlands, 52 km north of Quito.
Ciudad Mitad del Mundo
Ciudad Mitad del Mundo is a site owned by Pichincha province in San Antonio parish, 26 kilometers north of central Quito.
Pululahua Geobotanical Reserve
Surrounding Pululahua Volcano, this geobotanical reserve lies 17 km north of Quito in the northwestern part of the Pomasqui Valley, Pichincha province.
Jardín botánico La Carolina
Now named Jardín Botánico Padre Julio Marrero, this roughly 17-hectare botanical garden, palm collection and orchid house in Santo Domingo de los Colorados belongs to the Pontifical Catholic University of Ecuador.
More drives to Quevedo
More drives from Popayán
- Popayán to Tuluá
- Popayán to San Cipriano
- Popayán to Zipaquirá
- Popayán to Guatapé
- Popayán to Tunja
- Popayán to Sogamoso
Frequently asked questions
How long is the drive from Popayán to Quevedo, Ecuador?
About 14 h 17 min of driving without stops, over 523 miles.
How far is Quevedo, Ecuador from Popayán by car?
About 523 miles (842 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Popayán to Quevedo drive cross the border?
At about mile 215, from Colombia into Ecuador.
What do U.S. citizens need to drive from Popayán into Ecuador?
No visa needed unless you stay more than 90 days in any 12-month period. Passport: must be valid for 6 months beyond your arrival date. A valid U.S. license is recognized for up to 90 days. (U.S. State Department, updated February 18, 2026.)
Is it safe to drive from Popayán to Quevedo, Ecuador?
The U.S. State Department rates Colombia Level 3: Reconsider Travel; Ecuador Level 2: Exercise Increased Caution. Parts of this route are in or near areas rated Level 4: Do Not Travel (Colombia: Cauca (excluding Popayán); Ecuador: Quevedo, Quinsaloma, and Pueblo Viejo, in Los Rios province). Read the full advisory before you go.
What roads does the drive from Popayán to Quevedo use?
In order: 25 NR C, E35, E282, E28B, E28 and E25. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Popayán to Quevedo?
Closest to the road: St. Ezequiel Moreno Cathedral, Pasto (cathedral, mile 155, 1 mi from the route); Ciudad Mitad del Mundo (park, mile 366, 0.2 mi from the route); Jardín botánico La Carolina (botanical garden, mile 457, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.