Pergamino to Tacuarembó, Uruguay Road Trip: Route & Border

By admin, 13 October, 2026

Pergamino to Tacuarembó, Uruguay is about 399 road miles (642 km): roughly 8 h 13 min at the wheel if you don't stop. You cross from Argentina into Uruguay at about mile 253, at the Colón–Paysandú bridge.

U.S. State Department travel advisory: Argentina — Level 1, Exercise Normal Precautions; Uruguay — Level 2, Exercise Increased Caution

Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.

On the roads, the State Department says:

  • Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
  • Uruguay: “If you are in an accident involving injury, stay in place until a police officer arrives.”
Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldesCiervo de los Pantanos National ParkPozo HondoMuseo Carlos GardelArgentina–Uruguay borderPergaminoTacuarembó
Route from Pergamino to Tacuarembó with the 4 stops listed below (blue dots) and the approximate Argentina–Uruguay border crossing (red square).
Distance399 mi (642 km)
Time at the wheel, no stops8 h 13 min
Main roads, in orderRN8 → RN193 → RN12 → RN14 → RN135
Border crossingabout mile 253, Argentina → Uruguay (the Colón–Paysandú bridge)
Regions on the routeBuenos Aires, Entre Ríos, Paysandú, Salto, Tacuarembó
Fuel estimate (car at 25 mpg)about 16.0 gal; actual use varies by vehicle and traffic
Stops listed below4

The border on the way to Tacuarembó

The route crosses at about mile 253, at the Colón–Paysandú bridge, from Entre Ríos into Paysandú. Plan on two checks on each side: immigration for your passport and customs for the car.

Entering Uruguay (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date.
Driving in UruguayYou can drive on your U.S. license.
Entering Argentina (U.S. citizens)No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps.
Driving in ArgentinaA valid U.S. license usually works; an International Driving Permit is recommended.
Rental carCross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book.

Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.

What the drive from Pergamino to Tacuarembó is like

RN14 (93 mi) and RN8 (76 mi) carry about 42% of the 399 miles. The first 253 miles are in Argentina; the last 146 are in Uruguay. It runs through 5 regions: Buenos Aires, Entre Ríos, Paysandú, Salto, Tacuarembó. Of the 4 stops listed below, 2 are within a mile of the road.

Which roads connect Pergamino and Tacuarembó

RoadRoute miles (from–to)Length, miRegion
local roads0–44Buenos Aires
RN84–8076Buenos Aires
connecting roads80–811Buenos Aires
RN19381–10019Buenos Aires
RN12100–15050Buenos Aires, Entre Ríos
RN14150–24393Entre Ríos
connecting roads243–2441Entre Ríos
RN135244–2528Entre Ríos
local roads252–399147Entre Ríos, Paysandú, Salto, Tacuarembó
  • Mile 120 of this route: Buenos Aires → Entre Ríos (region line)
  • Mile 253 of this route: Entre Ríos → Paysandú (international border)
  • Mile 361 of this route: Paysandú → Salto (region line)
  • Mile 367 of this route: Salto → Paysandú (region line)
  • Mile 377 of this route: Paysandú → Tacuarembó (region line)

Breaking up the drive: stops between Pergamino and Tacuarembó

  • Right off the route (under 1 mile): Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (mile 69), Museo Carlos Gardel (mile 382)
  • Nature and outdoors: Ciervo de los Pantanos National Park (mile 103), Pozo Hondo (mile 380)
  • Museums and history: Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (mile 69), Museo Carlos Gardel (mile 382)

Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes

Mile 69 · Museum · 0.6 mi from the route

In San Antonio de Areco, Buenos Aires province, the Museo Gauchesco Ricardo Güiraldes spreads ten exhibit rooms across the 97-hectare Parque Criollo, opened in 1938, and presents Argentina's past, especially that of Buenos Aires province.

Ciervo de los Pantanos National Park

Mile 103 · National park · 12 mi from the route · side trip; actual detour depends on access roads

Marsh deer give their name to Ciervo de los Pantanos National Park, a Ramsar Site in Campana, Buenos Aires province, where waterbirds are abundant.

Pozo Hondo

Mile 380 · Waterfall · 2 mi from the route · side trip; actual detour depends on access roads

Pozo Hondo is a waterfall in Uruguay's Tacuarembó department, located between the towns of Valle Edén and Tambores.

Museo Carlos Gardel

Mile 382 · Museum · 0.4 mi from the route

Dedicated to the life and work of Carlos Gardel, this museum is in Valle Edén, Tacuarembó department, 21 kilometers from the city of Tacuarembó.

Once you reach Tacuarembó

Museo de Geociencias

Museum · in Tacuarembó

Museo del Indio y del Gaucho Washington Escobar

Museum · in Tacuarembó

The Museo del Indio y del Gaucho, a museum of the Indigenous people and the gaucho, is located in the city of Tacuarembó, Uruguay.

Museo de Artes Visuales de Tacuarembó

Museum · in Tacuarembó

The Museum of Visual Arts of Tacuarembó (Museo de Artes Visuales) is a museum in the city of Tacuarembó, Uruguay.

More drives to Tacuarembó

More drives from Pergamino

Frequently asked questions

How long is the drive from Pergamino to Tacuarembó, Uruguay?

About 8 h 13 min of driving without stops, over 399 miles.

How far is Tacuarembó, Uruguay from Pergamino by car?

About 399 miles (642 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Where does the Pergamino to Tacuarembó drive cross the border?

At about mile 253, from Argentina into Uruguay, at the Colón–Paysandú bridge.

What do U.S. citizens need to drive from Pergamino into Uruguay?

No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)

What does the U.S. travel advisory say about the Pergamino to Tacuarembó drive?

The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.

What roads does the drive from Pergamino to Tacuarembó use?

In order: RN8, RN193, RN12, RN14 and RN135. The road-by-road table above shows the route miles for each one.

What are good stops between Pergamino and Tacuarembó?

Closest to the road: Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes (museum, mile 69, 0.6 mi from the route); Pozo Hondo (waterfall, mile 380, 2 mi from the route); Museo Carlos Gardel (museum, mile 382, 0.4 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.