Plan on about 6 h 44 min of driving for the 331-mile (532 km) trip from Paraná to Durazno, Uruguay, before any stops. You cross from Argentina into Uruguay at about mile 186, at the Colón–Paysandú bridge.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Gas stations are often far apart and not always easily identified from the main roadway.”
- Uruguay: “Traffic fatalities are high in Uruguay.”
| Distance by road | 331 mi (532 km) |
|---|---|
| Time at the wheel, no stops | 6 h 44 min |
| Main roads, in order | RN12 → RP39 → RN14 → RN135 |
| Border crossing | about mile 186, Argentina → Uruguay (the Colón–Paysandú bridge) |
| Regions on the route | Entre Ríos, Paysandú, Río Negro, Flores, Durazno |
| Fuel estimate (car at 25 mpg) | about 13.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 3 |
The border on the way to Durazno
The route crosses at about mile 186, at the Colón–Paysandú bridge, from Entre Ríos into Paysandú. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
The Paraná–Durazno drive in a few lines
RN12 (93 mi) and RP39 (63 mi) carry about 47% of the 331 miles. The first 186 miles are in Argentina; the last 145 are in Uruguay. It runs through 5 regions: Entre Ríos, Paysandú, Río Negro, Flores, Durazno. Of the 3 stops listed below, 1 are within a mile of the road.
Paraná to Durazno: the road sequence
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–4 | 4 | Entre Ríos |
| RN12 | 4–97 | 93 | Entre Ríos |
| RP39 | 97–160 | 63 | Entre Ríos |
| connecting roads | 160–161 | 1 | Entre Ríos |
| RN14 | 161–177 | 16 | Entre Ríos |
| RN135 | 177–185 | 8 | Entre Ríos |
| local roads | 185–331 | 146 | Entre Ríos, Paysandú, Río Negro, Flores, Durazno |
- Mile 186 of this route: Entre Ríos → Paysandú (international border)
- Mile 219 of this route: Paysandú → Río Negro (region line)
- Mile 274 of this route: Río Negro → Flores (region line)
- Mile 326 of this route: Flores → Durazno (region line)
What to see on the way from Paraná to Durazno
- Right off the route (under 1 mile): Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 303)
- Nature and outdoors: Reserva de Flora y fauna Dr. Rodolfo Tálice (mile 303)
- Museums and history: San José palace (mile 147), Nuestra Señora del Rosario y San Benito de Palermo, Paysandú (mile 193)
San José palace
San José Palace was the home of Justo José de Urquiza, president of the Argentine Confederation from 1854 to 1860, and now houses the Justo José de Urquiza Museum and National Monument.
Nuestra Señora del Rosario y San Benito de Palermo, Paysandú
Paysandú's Catholic parish church of Our Lady of the Rosary and St. Benedict of Palermo was named a minor basilica in 1949 and remains an active parish of the city.
Reserva de Flora y fauna Dr. Rodolfo Tálice
Off Route 3 near Trinidad, the Dr. Rodolfo Tálice Ecopark (Reserva de Flora y Fauna Dr. Rodolfo Talice) is a fenced wildlife reserve where axis deer, greater rheas and pampas deer roam free alongside other species.
Once you reach Durazno
Casa de Rivera, Durazno
Facing Plaza Independencia in Durazno, the Casa de Fructuoso Rivera (Casa de Rivera) is one of the town's main heritage sites and now houses the department's historical museum.
More drives to Durazno
- Montevideo to Durazno
- Maldonado to Durazno
- Artigas to Durazno
- Buenos Aires to Durazno, Uruguay
- Rosario, Argentina to Durazno, Uruguay
- Mar del Plata to Durazno, Uruguay
More drives from Paraná
- Paraná to San Nicolás de los Arroyos
- Paraná to Pergamino
- Paraná to Arrecifes
- Paraná to San Antonio de Areco
- Paraná to Luján
- Paraná to Tigre
Frequently asked questions
How long is the drive from Paraná to Durazno, Uruguay?
About 6 h 44 min of driving without stops, over 331 miles.
How far is Durazno, Uruguay from Paraná by car?
About 331 miles (532 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Paraná to Durazno drive cross the border?
At about mile 186, from Argentina into Uruguay, at the Colón–Paysandú bridge.
What do U.S. citizens need to drive from Paraná into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from Paraná to Durazno, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Paraná to Durazno use?
In order: RN12, RP39, RN14 and RN135. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Paraná to Durazno?
Closest to the road: San José palace (museum, mile 147, 2 mi from the route); Nuestra Señora del Rosario y San Benito de Palermo, Paysandú (basilica, mile 193, 2 mi from the route); Reserva de Flora y fauna Dr. Rodolfo Tálice (botanical garden, mile 303, 0.2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.