The Wayro route from Orizaba to Tlaxcala is 112 miles (181 km), about 1 h 52 min of driving without stops.
| Distance | 112 mi (181 km) |
|---|---|
| Driving time, no stops | 1 h 52 min |
| Main roads, in order | MEX-150D → MEX-119D |
| Mexican states on the route | Veracruz (Level 2), Puebla (Level 2), Tlaxcala (Level 2) |
| Toll roads | MEX-150D, MEX-119D, MEX-117D |
| Fuel estimate (car at 25 mpg) | about 4.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 5 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Orizaba to Tlaxcala is like
MEX-150D (95 mi) and MEX-119D (10 mi) carry about 94% of the 112 miles. MEX-150D, MEX-119D are toll highways (cuota). It runs through 3 states: Veracruz, Puebla, Tlaxcala. Of the 5 stops listed below, 2 are within a mile of the road.
The route from Orizaba to Tlaxcala, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–3 | 3 | Veracruz |
| MEX-150D | 3–98 | 95 | Veracruz, Puebla |
| connecting roads | 98–99 | 1 | Puebla |
| MEX-119D | 99–109 | 10 | Puebla, Tlaxcala |
| local roads | 109–112 | 3 | Tlaxcala |
- Mile 23 of this route: Veracruz → Puebla (state line)
- Mile 101 of this route: Puebla → Tlaxcala (state line)
Stops between Orizaba and Tlaxcala
- Right off the route (under 1 mile): Cañón del Río Blanco National Park (mile 9), Parque ecológico Los Ladrillos (mile 103)
- Nature and outdoors: Cañón del Río Blanco National Park (mile 9), La Malinche National Park (mile 84), Parque ecológico Los Ladrillos (mile 103)
- Museums and history: Museo Regional de la Revolución Mexicana (mile 91)
Cañón del Río Blanco National Park
Cañón del Río Blanco National Park is a protected natural area in the Mexican state of Veracruz, set aside by the government as a national park.
La Malinche National Park
Tlaxcala's La Malinche National Park surrounds the inactive Matlalcuéyetl volcano, with pine, oak and fir forests on its slopes, hiking trails, birdwatching, and stone cabins and campsites at the Malintzi Vacation Center.
Museo Regional de la Revolución Mexicana
The Serdán family home in downtown Puebla, now the Museo Regional de la Revolución Mexicana, recalls Aquiles, Máximo and Carmen Serdán and the start of the 1910 Revolution. It opened in 1960.
Convento de Huejotzingo
Founded by Franciscans in the 16th century, the former convent of San Miguel Arcángel in Huejotzingo shows colonial Plateresque architecture on the western slopes of Popocatépetl and Iztaccíhuatl. UNESCO declared it a World Heritage Site in 1994.
Parque ecológico Los Ladrillos
Opened on April 2, 2015, Los Ladrillos Ecological Park is a nature reserve in the municipality of Zacatelco, in Tlaxcala.
When you get to Tlaxcala
Teatro Xicohténcatl
Tlaxcala's Teatro Xicohténcatl opened in 1873 and was reopened in 1888 after remodeling. Look up to see John Fulton's ceiling mural of the nine muses, painted in Art Nouveau style against a Tlaxcalan landscape.
Tlaxcala Cathedral
Part of a 16th-century Franciscan complex among the earliest in the Americas, Tlaxcala's cathedral is famous for its carved Mudéjar-style wooden ceiling. Look for the freestanding bell tower and the stone font where Tlaxcalan lords were baptized.
Museo Miguel N. Lira
Downtown Tlaxcala's Museo Miguel N. Lira fills the old State Printing Office, linked to the writer and poet. Visitors see his manuscripts, family photos and personal belongings, plus the original linotype machines and the press that printed his work.
More drives to Tlaxcala
- Cuautla to Tlaxcala
- Toluca to Tlaxcala
- Cuernavaca to Tlaxcala
- San Juan del Río to Tlaxcala
- Zitácuaro to Tlaxcala
- San Miguel de Allende to Tlaxcala
From Orizaba to other places in Mexico
- Orizaba to Zacatelco
- Orizaba to Apizaco
- Orizaba to Chiautempan
- Orizaba to Huejotzingo
- Orizaba to Calpulalpan
- Orizaba to Ocuituco
Continue Your Adventure
Frequently asked questions
How long is the drive from Orizaba to Tlaxcala?
About 1 h 52 min of driving without stops, over 112 miles.
How far is Tlaxcala from Orizaba by car?
About 112 miles (181 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Orizaba to Tlaxcala?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Orizaba to Tlaxcala?
The U.S. State Department rates Veracruz Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Orizaba to Tlaxcala use?
In order: MEX-150D and MEX-119D. The road-by-road table above shows the route miles and states for each one.
What are good stops between Orizaba and Tlaxcala?
Closest to the road: Cañón del Río Blanco National Park (National Park of Mexico, mile 9, 0.6 mi from the route); Museo Regional de la Revolución Mexicana (museum, mile 91, 3 mi from the route); Parque ecológico Los Ladrillos (park, mile 103, 0.4 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.