5 stops between Papallacta and Mindo, plus the route: 100 miles (161 km), about 2 h 35 min of driving and the U.S. travel advisory level.

Driving from Quito to Esmeraldas: 199 miles, roughly 4 h 34 min without stops. Road by road, 3 places to stop and the State Department advisory.

3 stops between Quito and Santo Domingo de los Colorados, plus the route: 112 miles (180 km), about 2 h 43 min of driving and the U.S. travel advisory level.

3 stops between Quito and Mindo, plus the route: 64 miles (103 km), about 1 h 36 min of driving and the U.S. travel advisory level.

Driving from Colón, Panama to Las Lajas: 261 miles, roughly 6 h 18 min without stops. Road by road, 6 places to stop and the State Department advisory.

Driving from Santa Catalina to Portobelo: 270 miles, roughly 7 h 24 min without stops. Road by road, 6 places to stop and the State Department advisory.

Colón, Panama to Santa Catalina: 255 miles (411 km), about 6 h 47 min of driving. The route, U.S. travel advisory for Panama and 7 stops on the way.

Driving from Panama City to Santa Catalina: 224 miles, roughly 6 h 6 min without stops. Road by road, 6 places to stop and the State Department advisory.

Driving from Santa Catalina to Coronado: 172 miles, roughly 4 h 57 min without stops. Road by road, 3 places to stop and the State Department advisory.

Driving from Santiago de Veraguas to Portobelo: 203 miles, roughly 5 h 20 min without stops. Road by road, 6 places to stop and the State Department advisory.