Matehuala to Tlaltizapán Road Trip: Route, Tolls & Stops

By admin, 13 October, 2026

Matehuala to Tlaltizapán is about 436 road miles (701 km): roughly 8 h 33 min at the wheel if you don't stop.

U.S. State Department travel advisory: San Luis Potosí — Level 2, Exercise Increased Caution; Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Mexico City — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Tlaltizapán. Check the full advisory for this state before you go.
San Luis Potosí CathedralHistoric Monuments Zone of QuerétaroMuseo Nacional del VirreinatoMuseo Nacional de San CarlosMuseo Casa de Carranza, Mexico CityParque de la BombillaMuseo Universitario de Ciencias y ArtesCuicuilcoTeopanzolcoMatehualaTlaltizapán
Route from Matehuala to Tlaltizapán with the 9 stops listed below (blue dots).
Distance by road436 mi (701 km)
Driving time, no stops8 h 33 min
Main roads, in orderMEX-57 → MEX-57D → Periférico → MEX-95D → MEX-95 → MOR 14
Mexican states on the routeSan Luis Potosí, Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos
Toll roads (as marked in OpenStreetMap)MEX-57D, MEX-95D
Fuel estimate (car at 25 mpg)about 17.4 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

Driving Matehuala to Tlaltizapán: the shape of the trip

MEX-57 (184 mi) and MEX-57D (166 mi) carry about 80% of the 436 miles. It runs through 7 states: San Luis Potosí, Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos. OpenStreetMap marks tolled sections on MEX-57D and MEX-95D. Of the 9 stops listed below, 2 are within a mile of the road.

Roads you'll take from Matehuala to Tlaltizapán

RoadRoute miles (from–to)Length, miState
local roads0–22San Luis Potosí
MEX-572–8078San Luis Potosí
MEX-57D80–12242San Luis Potosí
MEX-57122–21997San Luis Potosí, Guanajuato, Querétaro
connecting roads219–2212Querétaro
MEX-57D221–345124Querétaro, State of Mexico, Hidalgo
MEX-57345–3549State of Mexico
Periférico354–37319State of Mexico, Mexico City
connecting roads373–3752Mexico City
MEX-95D375–39621Mexico City, Morelos
connecting roads396–40610Morelos
MEX-95406–4148Morelos
MEX-95D414–4239Morelos
connecting roads423–4241Morelos
MOR 14424–4306Morelos
local roads430–4366Morelos
  • Mile 160 of this route: San Luis Potosí → Guanajuato (state line)
  • Mile 213 of this route: Guanajuato → Querétaro (state line)
  • Mile 274 of this route: Querétaro → State of Mexico (state line)
  • Mile 307 of this route: State of Mexico → Hidalgo (state line)
  • Mile 327 of this route: Hidalgo → State of Mexico (state line)
  • Mile 359 of this route: State of Mexico → Mexico City (state line)
  • Mile 391 of this route: Mexico City → Morelos (state line)

Where to stop on the way to Tlaltizapán

  • Right off the route (under 1 mile): Museo Nacional del Virreinato (mile 337), Cuicuilco (mile 371)
  • Nature and outdoors: Parque de la Bombilla (mile 365)
  • Museums and history: San Luis Potosí Cathedral (mile 114), Museo Nacional del Virreinato (mile 337), Museo Nacional de San Carlos (mile 360), Museo Casa de Carranza, Mexico City (mile 360), Museo Universitario de Ciencias y Artes (mile 366), Cuicuilco (mile 371), Teopanzolco (mile 411)

San Luis Potosí Cathedral

Mile 114 · Cathedral · 9 mi from the route · side trip; actual detour depends on access roads

Look closely at the two towers of San Luis Potosí's cathedral: one is built of mortar, the other of quarried cantera stone. The Baroque church is the seat of the archdiocese.

Historic Monuments Zone of Querétaro

Mile 237 · Old town · 7 mi from the route · side trip; actual detour depends on access roads

Querétaro's historic center, a UNESCO World Heritage site since 1996, pairs the Spaniards' grid of streets with the winding lanes of the old Indigenous quarters. Walk it for Baroque churches and mansions of the 17th and 18th centuries and the city's landmark aqueduct.

Museo Nacional del Virreinato

Mile 337 · Museum · 0.9 mi from the route

Housed in the former Jesuit college of San Francisco Javier in Tepotzotlán, begun in 1606, this national museum covers three centuries of colonial art. Its Baroque church, built 1670-1682, keeps altarpieces designed by Miguel Cabrera and Higinio de Chávez.

Museo Nacional de San Carlos

Mile 360 · National museum · 3 mi from the route · side trip; actual detour depends on access roads

Mexico City's Museo Nacional de San Carlos, in the Cuauhtémoc borough, is a national art museum devoted to European art.

Museo Casa de Carranza, Mexico City

Mile 360 · Museum · 2 mi from the route · side trip; actual detour depends on access roads

Venustiano Carranza spent the last six months of his life in this house in Mexico City's Colonia Cuauhtémoc, now the Museo Casa de Carranza.

Parque de la Bombilla

Mile 365 · Park · 1 mi from the route

In San Ángel, Parque de la Bombilla holds the monument to Álvaro Obregón, built where the president-elect was assassinated in 1928 while dining at the La Bombilla restaurant.

Museo Universitario de Ciencias y Artes

Mile 366 · Museum · 1 mi from the route

MUCA, the Museo Universitario de Ciencias y Artes, is a university venue that promotes multidisciplinary exhibitions and also offers academic and outreach activities.

Cuicuilco

Mile 371 · Archaeological site · 0.1 mi from the route

In Mexico City's Tlalpan borough, Cuicuilco preserves a pyramid whose construction began a few centuries BCE, during the Late Preclassic period, near the old southern shore of Lake Texcoco.

Teopanzolco

Mile 411 · Archaeological site · 1 mi from the route

Now surrounded by the city of Cuernavaca, Teopanzolco preserves a Late Postclassic pyramid base that once carried twin temples to Tlaloc and Huitzilopochtli, a layout closely tied to Tenochtitlan's sacred precinct.

More drives to Tlaltizapán

From Matehuala to other places in Mexico

Frequently asked questions

How long is the drive from Matehuala to Tlaltizapán?

About 8 h 33 min of driving without stops, over 436 miles.

How far is Tlaltizapán from Matehuala by car?

About 436 miles (701 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Matehuala to Tlaltizapán?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Matehuala to Tlaltizapán?

The U.S. State Department rates San Luis Potosí Level 2: Exercise Increased Caution; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Mexico City Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

Which highways go from Matehuala to Tlaltizapán?

In order: MEX-57, MEX-57D, Periférico, MEX-95D, MEX-95 and MOR 14. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Matehuala to Tlaltizapán?

Closest to the road: Museo Nacional del Virreinato (museum, mile 337, 0.9 mi from the route); Parque de la Bombilla (park, mile 365, 1 mi from the route); Cuicuilco (archaeological site, mile 371, 0.1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.