Matehuala to La Manzanilla Road Trip: Where to Stop on the Way

By admin, 13 October, 2026

Matehuala to La Manzanilla is about 544 road miles (875 km): roughly 10 h 7 min at the wheel if you don't stop.

U.S. State Department travel advisory: San Luis Potosí — Level 2, Exercise Increased Caution; Guanajuato — Level 3, Reconsider Travel; Jalisco — Level 3, Reconsider Travel; Colima — Level 4, Do Not TravelAdvisory issued May 29, 2026; checked September 29, 2026. Jalisco is the Mexican state that contains La Manzanilla. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Cineteca AlamedaMuseo Laberinto de las Ciencias y las ArtesTeatro José Rosas MorenoTeocaltitan Archaeological SiteMuseum of Paleontology of GuadalajaraCasa Museo López PortilloVolcán Nevado de Colima National ParkEl ChanalAlfonso Michel University Art GalleryMatehualaLa Manzanilla
Route from Matehuala to La Manzanilla with the 9 stops listed below (blue dots).
Distance by road544 mi (875 km)
Driving time, no stops10 h 7 min
Main roads, in orderMEX-57 → MEX-57D → MEX-70 → MEX-80 → MEX-80D → MEX-15D → MEX-15 → MEX-54D → MEX-54 → MEX-110 → MEX-200D → MEX-200
Mexican states on the routeSan Luis Potosí, Guanajuato, Jalisco, Colima
Toll roads (as marked in OpenStreetMap)MEX-57D, MEX-80D, MEX-90D, MEX-15D
Fuel estimate (car at 25 mpg)about 21.7 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Matehuala to La Manzanilla is like

MEX-80D (127 mi) and MEX-57 (94 mi) carry about 41% of the 544 miles. It runs through 4 states: San Luis Potosí, Guanajuato, Jalisco, Colima. OpenStreetMap marks tolled sections on MEX-57D, MEX-80D and MEX-90D. Of the 9 stops listed below, 1 are within a mile of the road.

Matehuala to La Manzanilla: the road sequence

RoadRoute miles (from–to)Length, miState
local roads0–22San Luis Potosí
MEX-572–8078San Luis Potosí
MEX-57D80–10121San Luis Potosí
MEX-57101–11716San Luis Potosí
local roads117–12710San Luis Potosí
MEX-57D127–1369San Luis Potosí
MEX-70136–15317San Luis Potosí
MEX-80153–1574San Luis Potosí
MEX-80D157–19841San Luis Potosí, Guanajuato, Jalisco
MEX-80198–23133Jalisco
MEX-80D231–31786Jalisco
MEX-15D317–3225Jalisco
local roads322–3264Jalisco
MEX-15326–34418Jalisco
MEX-54D344–43288Jalisco, Colima
MEX-54432–4408Colima
MEX-110440–46525Colima
connecting roads465–4672Colima
MEX-200D467–50538Colima
MEX-200505–54338Colima, Jalisco
local roads543–5441Jalisco
  • Mile 163 of this route: San Luis Potosí → Guanajuato (state line)
  • Mile 174 of this route: Guanajuato → Jalisco (state line)
  • Mile 424 of this route: Jalisco → Colima (state line)
  • Mile 520 of this route: Colima → Jalisco (state line)

Breaking up the drive: stops between Matehuala and La Manzanilla

  • Right off the route (under 1 mile): Teatro José Rosas Moreno (mile 208)
  • Nature and outdoors: Volcán Nevado de Colima National Park (mile 419)
  • Museums and history: Museo Laberinto de las Ciencias y las Artes (mile 121), Teatro José Rosas Moreno (mile 208), Teocaltitan Archaeological Site (mile 244), Museum of Paleontology of Guadalajara (mile 321), Casa Museo López Portillo (mile 322), El Chanal (mile 436), Alfonso Michel University Art Gallery (mile 439)

Cineteca Alameda

Mile 119 · Cinematheque · 1 mi from the route

San Luis Potosí's Cineteca Alameda screens Mexican and international films in the 1940s Teatro Alameda building facing the Alameda Juan Sarabia, and also hosts concerts.

Museo Laberinto de las Ciencias y las Artes

Mile 121 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Built in Parque Tangamanga I and opened on September 4, 2008, the Museo Laberinto de las Ciencias y las Artes is an interactive museum in San Luis Potosí.

Teatro José Rosas Moreno

Mile 208 · Opera house · 0.3 mi from the route

Construction of the Teatro José Rosas Moreno in Lagos de Moreno began in 1867, and the theater opened on May 5, 1907. It is named for Jalisco writer José Rosas Moreno.

Teocaltitan Archaeological Site

Mile 244 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

Near Jalostotitlán in the Los Altos region, the Teocaltitán site holds pyramids, sunken patios and a ball court spread across about nine hectares, built by a people who dominated much of the area from AD 400 to 900.

Museum of Paleontology of Guadalajara

Mile 321 · Museum · 1 mi from the route

Fossils are the focus at Guadalajara's Museum of Paleontology, which opened in 2000 inside Parque Agua Azul with exhibits developed alongside INAH, Mexico's national anthropology and history institute.

Casa Museo López Portillo

Mile 322 · Museum · 2 mi from the route · side trip; actual detour depends on access roads

Opened on May 10, 1982, this house museum in Guadalajara's historic center showcases decorative arts and promotes work by young artists from the metro area.

Volcán Nevado de Colima National Park

Mile 419 · National park · 4 mi from the route · side trip; actual detour depends on access roads

This national park in western Mexico protects the upper slopes of two volcanic peaks, Volcán de Colima and Nevado de Colima, in the states of Jalisco and Colima.

El Chanal

Mile 436 · Archaeological site · 2 mi from the route · side trip; actual detour depends on access roads

North of Colima city, this Postclassic settlement straddles the Colima River. Its ceremonial core holds temples, palaces, altars and a ballcourt, and digs revealed copper, silver and gold metalwork along with pottery and obsidian tools.

Alfonso Michel University Art Gallery

Mile 439 · Museum · 2 mi from the route

Two restored old houses in downtown Colima hold this art gallery (Pinacoteca Universitaria Alfonso Michel), which honors painter Alfonso Michel and displays a large collection belonging to the University of Colima.

More drives to La Manzanilla

From Matehuala to other places in Mexico

Frequently asked questions

How long does it take to drive from Matehuala to La Manzanilla?

About 10 h 7 min of driving without stops, over 544 miles.

How far is La Manzanilla from Matehuala by car?

About 544 miles (875 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Matehuala to La Manzanilla?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Matehuala to La Manzanilla?

The U.S. State Department rates San Luis Potosí Level 2: Exercise Increased Caution; Guanajuato Level 3: Reconsider Travel; Jalisco Level 3: Reconsider Travel; Colima Level 4: Do Not Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Matehuala to La Manzanilla use?

In order: MEX-57, MEX-57D, MEX-70, MEX-80, MEX-80D, MEX-15D, MEX-15, MEX-54D, MEX-54, MEX-110, MEX-200D and MEX-200. The road-by-road table above shows the route miles for each one.

Where can you stop on the way from Matehuala to La Manzanilla?

Closest to the road: Cineteca Alameda (cinematheque, mile 119, 1 mi from the route); Teatro José Rosas Moreno (opera house, mile 208, 0.3 mi from the route); Museum of Paleontology of Guadalajara (museum, mile 321, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.