Manzanillo to Apizaco Road Trip: Where to Stop on the Way

By admin, 3 October, 2026

The Wayro route from Manzanillo to Apizaco is 536 miles (862 km), about 9 h 44 min of driving without stops.

U.S. State Department travel advisory: Colima — Level 4, Do Not Travel; Jalisco — Level 3, Reconsider Travel; Michoacán — Level 4, Do Not Travel; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Tlaxcala — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Tlaxcala is the Mexican state that contains Apizaco. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Museo Comunitario de la SalMuseo Universitario de Artes Populares María Teresa PomarVolcán Nevado de Colima National ParkTeatro Morelos de MaravatíoRayón National ParkAtlantean figuresTeotihuacanAqueduct of Padre TemblequeManzanilloApizaco
Route from Manzanillo to Apizaco with the 8 stops listed below (blue dots).
Distance536 mi (862 km)
Driving time, no stops9 h 44 min
Main roads, in orderMEX-200 → MEX-200D → MEX-110 → MEX-54 → MEX-54D → MEX-15 → MEX-15D → MEX-M40D → MEX-136
Mexican states on the routeColima (Level 4), Jalisco (Level 3), Michoacán (Level 4), State of Mexico (Level 2), Hidalgo (Level 2), Tlaxcala (Level 2)
Toll roadsMEX-200D, MEX-54D, MEX-15D, MEX-M40D
Fuel estimate (car at 25 mpg)about 21.4 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Manzanillo to Apizaco is like

MEX-15D (189 mi) and MEX-M40D (121 mi) carry about 58% of the 536 miles. MEX-200D, MEX-54D, MEX-15D, MEX-M40D are toll highways (cuota); MEX-200, MEX-110, MEX-54, MEX-15, MEX-136 are free federal roads (libre). It runs through 6 states: Colima, Jalisco, Michoacán, State of Mexico, Hidalgo, Tlaxcala. Of the 8 stops listed below, 1 are within a mile of the road.

The route from Manzanillo to Apizaco, road by road

RoadRoute miles (from–to)Length, miState
local roads0–33Colima
MEX-2003–96Colima
MEX-200D9–3526Colima
connecting roads35–383Colima
MEX-11038–6325Colima
MEX-5463–707Colima
MEX-54D70–9424Colima, Jalisco
MEX-5494–10410Jalisco
MEX-110104–16864Jalisco, Michoacán
connecting roads168–1702Michoacán
MEX-15170–1766Michoacán
MEX-110176–19418Michoacán
connecting roads194–1984Michoacán, Jalisco
MEX-15D198–387189Jalisco, Michoacán, State of Mexico
MEX-M40D387–508121State of Mexico, Hidalgo, Tlaxcala
connecting roads508–5091Tlaxcala
MEX-136509–53627Tlaxcala
  • Mile 80 of this route: Colima → Jalisco (state line)
  • Mile 146 of this route: Jalisco → Michoacán (state line)
  • Mile 195 of this route: Michoacán → Jalisco (state line)
  • Mile 201 of this route: Jalisco → Michoacán (state line)
  • Mile 369 of this route: Michoacán → State of Mexico (state line)
  • Mile 419 of this route: State of Mexico → Hidalgo (state line)
  • Mile 449 of this route: Hidalgo → State of Mexico (state line)
  • Mile 464 of this route: State of Mexico → Hidalgo (state line)
  • Mile 480 of this route: Hidalgo → State of Mexico (state line)
  • Mile 493 of this route: State of Mexico → Hidalgo (state line)
  • Mile 500 of this route: Hidalgo → Tlaxcala (state line)

Stops between Manzanillo and Apizaco

  • Right off the route (under 1 mile): Museo Comunitario de la Sal (mile 26)
  • Nature and outdoors: Volcán Nevado de Colima National Park (mile 83), Rayón National Park (mile 366)
  • Museums and history: Museo Comunitario de la Sal (mile 26), Museo Universitario de Artes Populares María Teresa Pomar (mile 65), Teatro Morelos de Maravatío (mile 348), Teotihuacan (mile 481)

Museo Comunitario de la Sal

Mile 26 · Museum · 0.4 mi from the route

Set in an old warehouse in Cuyutlán, the community Salt Museum (Museo Comunitario de la Sal) explains how local salt has been harvested, from the old tapeixtle technique to modern methods, with historic photos of the salt works.

Museo Universitario de Artes Populares María Teresa Pomar

Mile 65 · Art gallery · 1 mi from the route

Founded by collector María Teresa Pomar and run by the University of Colima, this museum is dedicated to Mexican folk art and handcrafts (artesanía), with pieces from across the country as well as the traditions of Colima state.

Volcán Nevado de Colima National Park

Mile 83 · National Park of Mexico · 4 mi from the route · side trip; actual detour depends on access roads

This national park in western Mexico protects the upper slopes of two volcanic peaks, Volcán de Colima and Nevado de Colima, in the states of Jalisco and Colima.

Teatro Morelos de Maravatío

Mile 348 · Opera house · 1 mi from the route

Maravatío's Teatro Morelos is a late-19th-century theater in a French-influenced neoclassical style, designed by architect Rafael Guerrero Torres. It opened on January 11, 1879, with a performance by opera singer Ángela Peralta.

Rayón National Park

Mile 366 · National Park of Mexico · 5 mi from the route · side trip; actual detour depends on access roads

Just outside Tlalpujahua, Rayón National Park (Parque Nacional Rayón) marks the start of the area's famous butterfly reserve country, which stretches south and west from here.

Atlantean figures

Mile 432 · Atlantean figures · 1 mi from the route

Crowning the main pyramid at the Tula archaeological zone, these basalt sculptures of Toltec warriors stand more than four meters tall in what was once the Toltec capital; the nearby Wall of Snakes shows carved serpents devouring skeletons.

Teotihuacan

Mile 481 · Historic site · 13 mi from the route · side trip; actual detour depends on access roads

Built between the 1st and 7th centuries AD, this UNESCO-listed ancient city lines the Avenue of the Dead, where you can walk between the Pyramid of the Sun, the Pyramid of the Moon and the Temple of the Feathered Serpent.

Aqueduct of Padre Tembleque

Mile 483 · Aqueduct · 2 mi from the route

Built by Franciscan friar Francisco de Tembleque between 1554 and 1572, this 16th-century water system runs more than 48 km between Zempoala and Otumba. Its tallest arcade at Tepeyahualco reaches almost 40 meters, and UNESCO listed it in 2015.

When you get to Apizaco

Basílica de Nuestra Señora de las Misericordias, Apizaco

Basilica · in Apizaco

In the city of Apizaco, this Catholic basilica (Basílica de Nuestra Señora de la Misericordia) was begun in the third decade of the 20th century and completed in 1961.

Museo Casa de Piedra

Railway museum · in Apizaco

Apizaco's old railroad station, dating from 1916, now houses the Museo Casa de Piedra. Inside, photographs and documents trace the town's history, especially its long ties to the railroads.

Ex Convento de Santa María de la Concepción Atlihuetzia

Convent · in Apizaco

The ruined walls of this 16th-century Franciscan convent in Atlihuetzia rise as high as 21 meters beside the 17th-century Purísima Concepción church. The site also holds a sanctuary to Cristóbal, honored as the first Catholic child martyr in the Americas.

More drives to Apizaco

From Manzanillo to other places in Mexico

Frequently asked questions

How long is the drive from Manzanillo to Apizaco?

About 9 h 44 min of driving without stops, over 536 miles.

How far is Apizaco from Manzanillo by car?

About 536 miles (862 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Manzanillo to Apizaco?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Manzanillo to Apizaco?

The U.S. State Department rates Colima Level 4: Do Not Travel; Jalisco Level 3: Reconsider Travel; Michoacán Level 4: Do Not Travel; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Manzanillo to Apizaco use?

In order: MEX-200, MEX-200D, MEX-110, MEX-54, MEX-54D, MEX-15, MEX-15D, MEX-M40D and MEX-136. The road-by-road table above shows the route miles and states for each one.

What are good stops between Manzanillo and Apizaco?

Closest to the road: Museo Comunitario de la Sal (museum, mile 26, 0.4 mi from the route); Teatro Morelos de Maravatío (opera house, mile 348, 1 mi from the route); Atlantean figures (atlantean figures, mile 432, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.