Plan on about 8 h 32 min of driving for the 406-mile (654 km) trip from Maldonado to San Antonio de Areco, Argentina, before any stops. You cross from Uruguay into Argentina at about mile 262, at the Gualeguaychú–Fray Bentos bridge.
Full advisory: Uruguay, Argentina. Advisory issued: Uruguay July 28, 2026; Argentina July 10, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Uruguay: “If you are in an accident involving injury, stay in place until a police officer arrives.”
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
| Distance | 406 mi (654 km) |
|---|---|
| Driving time, no stops | 8 h 32 min |
| Main roads, in order | I-B → RN136 → RN14 → RN12 → RN193 → RN8 |
| Border crossing | about mile 262, Uruguay → Argentina (the Gualeguaychú–Fray Bentos bridge) |
| Regions on the route | Maldonado, Canelones, San José, Colonia, Soriano, Río Negro, Entre Ríos, Buenos Aires |
| Fuel estimate (car at 25 mpg) | about 16.2 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
The border on the way to San Antonio de Areco
The route crosses at about mile 262, at the Gualeguaychú–Fray Bentos bridge, from Río Negro into Entre Ríos. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
|---|---|
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
| Driving in Uruguay | You can drive on your U.S. license. |
| The car, entering Argentina | Argentine customs (ARCA) registers the car's temporary entry. Bring the title or registration, liability insurance valid in Argentina and, if you don't own the car, a power of attorney signed before a notary. A rental car needs the rental company's MERCOSUR circulation authorization (ACM), and the company must be registered with Argentine customs. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Argentina (updated July 16, 2026); U.S. State Department, Uruguay (updated August 13, 2026); ARCA (Argentine customs). Checked October 10, 2026; rules change, so confirm before you go.
On the road from Maldonado to San Antonio de Areco
RN12 (49 mi) and RN14 (37 mi) carry about 21% of the 406 miles. The first 262 miles are in Uruguay; the last 144 are in Argentina. It runs through 8 regions: Maldonado, Canelones, San José, Colonia, Soriano, Río Negro, Entre Ríos, Buenos Aires. Of the 9 stops listed below, 4 are within a mile of the road.
Roads you'll take from Maldonado to San Antonio de Areco
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–9 | 9 | Maldonado |
| I-B | 9–27 | 18 | Maldonado |
| connecting roads | 27–28 | 1 | Maldonado |
| local roads | 28–44 | 16 | Maldonado, Canelones |
| connecting roads | 44–45 | 1 | Canelones |
| local roads | 45–56 | 11 | Canelones |
| connecting roads | 56–57 | 1 | Canelones |
| local roads | 57–89 | 32 | Canelones |
| connecting roads | 89–93 | 4 | Canelones |
| local roads | 93–124 | 31 | Canelones, San José |
| connecting roads | 124–127 | 3 | San José |
| local roads | 127–260 | 133 | San José, Colonia, Soriano, Río Negro |
| connecting roads | 260–263 | 3 | Río Negro, Entre Ríos |
| RN136 | 263–283 | 20 | Entre Ríos |
| local roads | 283–289 | 6 | Entre Ríos |
| RN14 | 289–326 | 37 | Entre Ríos |
| RN12 | 326–375 | 49 | Entre Ríos, Buenos Aires |
| RN193 | 375–395 | 20 | Buenos Aires |
| RN8 | 395–402 | 7 | Buenos Aires |
| local roads | 402–406 | 4 | Buenos Aires |
- Mile 34 of this route: Maldonado → Canelones (region line)
- Mile 103 of this route: Canelones → San José (region line)
- Mile 146 of this route: San José → Colonia (region line)
- Mile 163 of this route: Colonia → Soriano (region line)
- Mile 245 of this route: Soriano → Río Negro (region line)
- Mile 262 of this route: Río Negro → Entre Ríos (international border)
- Mile 355 of this route: Entre Ríos → Buenos Aires (region line)
Places worth a stop between Maldonado and San Antonio de Areco
- Right off the route (under 1 mile): Teatro Politeama (mile 91), Teatro Macció (mile 126), Museo Departamental de San José (mile 126), Cathedral of Mercedes (mile 243)
- Nature and outdoors: Cerro Pan de Azúcar Native Wildlife Breeding Station (mile 19), Laguna del Cisne (mile 57), Ciervo de los Pantanos National Park (mile 372)
- Museums and history: Iglesia de Cristo Obrero y Nuestra Señora de Lourdes (mile 56), Museo Departamental de San José (mile 126), Cathedral of Mercedes (mile 243), Gualeguaychú Cathedral (mile 284)
Cerro Pan de Azúcar Native Wildlife Breeding Station
Near Piriápolis in Maldonado, this breeding station for native wildlife on Cerro Pan de Azúcar is surrounded by native vegetation and offers guided visits, including a native wildlife trail and a path up the hill.
Iglesia de Cristo Obrero y Nuestra Señora de Lourdes
Wavy brick walls and a rippling brick roof define this church in Estación Atlántida, along with an openwork brick bell tower and a baptistery set underground. Engineer Eladio Dieste designed it, and it opened in 1960.
Laguna del Cisne
Near Salinas in Canelones, Laguna del Cisne is a subtropical lagoon of about 1.8 km², fed by a watershed of some 50 km², that has supplied drinking water to the Costa de Oro area since 1970.
Teatro Politeama
Canelones' Teatro Politeama opened in 1921 and reopened in 2014 as the Complejo Cultural Politeama Teatro Atahualpa del Cioppo. Uruguay declared the theater a National Historic Monument in 2022.
Teatro Macció
San José de Mayo's Teatro Bartolomé Macció is a traditional theater, regarded as the city's most important building architecturally and declared a Historic Monument of Uruguay in 1984.
Museo Departamental de San José
Set in central San José de Mayo, the Museo Departamental de San José is a history and fine arts museum that also runs a library, archives and cultural programs.
Cathedral of Mercedes
Mercedes, Uruguay, centers its Catholic life on the Cathedral of Our Lady of Mercy, which became the seat of the local diocese in 1960.
Gualeguaychú Cathedral
St. Joseph's Cathedral, also called Gualeguaychú Cathedral, is the mother church of the Roman Catholic Diocese of Gualeguaychú in Argentina.
Ciervo de los Pantanos National Park
Marsh deer give their name to Ciervo de los Pantanos National Park, a Ramsar Site in Campana, Buenos Aires province, where waterbirds are abundant.
Once you reach San Antonio de Areco
Parque Criollo y Museo Gauchesco Ricardo Gu͏̈iraldes
In San Antonio de Areco, Buenos Aires province, the Museo Gauchesco Ricardo Güiraldes spreads ten exhibit rooms across the 97-hectare Parque Criollo, opened in 1938, and presents Argentina's past, especially that of Buenos Aires province.
More drives to San Antonio de Areco
- Buenos Aires to San Antonio de Areco
- Adrogué to San Antonio de Areco
- La Plata to San Antonio de Areco
- Berisso to San Antonio de Areco
- Chascomús to San Antonio de Areco
- Villa Gesell to San Antonio de Areco
More drives from Maldonado
- Maldonado to Nueva Helvecia
- Maldonado to Colonia del Sacramento
- Maldonado to Carmelo
- Maldonado to Tacuarembó
- Maldonado to Rivera
- Maldonado to Artigas
Frequently asked questions
How long is the drive from Maldonado to San Antonio de Areco, Argentina?
About 8 h 32 min of driving without stops, over 406 miles.
What is the driving distance from Maldonado to San Antonio de Areco, Argentina?
About 406 miles (654 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the Maldonado to San Antonio de Areco drive cross the border?
At about mile 262, from Uruguay into Argentina, at the Gualeguaychú–Fray Bentos bridge.
What do U.S. citizens need to drive from Maldonado into Argentina?
No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. A valid U.S. license usually works; an International Driving Permit is recommended. (U.S. State Department, updated July 16, 2026.)
What does the U.S. travel advisory say about the Maldonado to San Antonio de Areco drive?
The U.S. State Department rates Uruguay Level 2: Exercise Increased Caution; Argentina Level 1: Exercise Normal Precautions. Read the full advisory before you go.
What roads does the drive from Maldonado to San Antonio de Areco use?
In order: I-B, RN136, RN14, RN12, RN193 and RN8. The road-by-road table above shows the route miles for each one.
What are good stops between Maldonado and San Antonio de Areco?
Closest to the road: Teatro Politeama (theater, mile 91, 0.2 mi from the route); Museo Departamental de San José (history museum, mile 126, 0.7 mi from the route); Cathedral of Mercedes (cathedral, mile 243, 0.7 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.