Mackinac Island to Oxford OH: Epic Great Lakes Road Trip Guide

Did you know that Mackinac Island, famous for banning motor vehicles, connects to Oxford, Ohio—home of Miami University—via a route that crosses the mighty Mackinac Bridge, the longest suspension bridge in the Western Hemisphere? This road trip covers roughly 500 miles, blending Great Lakes splendor with Midwestern charm.

Planning your journey involves navigating US-2, I-75, and US-23. Expect a drive time of about 8 hours without stops, but you'll want to linger. Here’s how to maximize your adventure.

This route is best driven over 3-4 days to fully experience the diversity between Michigan’s Upper Peninsula and Ohio’s college town. You must take a ferry from Mackinac Island to St. Ignace (30 min). From there, follow US-2 west to I-75 south.

• Ferry cost: $29 adult round trip (Shepler’s or Star Line)
• Bridge toll: $4 per car for Mackinac Bridge
• Fuel stops: Plentiful along I-75, recommend filling up in Gaylord or Grayling

Northern Michigan offers pristine forests and lakes. The Huron National Forest near Grayling provides hiking and fishing. Further south, the Flint area is industrial but has the historic Durant-Dort Carriage Company.

For culture, consider the how to find the best stops and hidden gems between cities article. Hidden gems include the Kitch-iti-kipi spring in Palms Book State Park and the Crossroads Village in Flint.

Road quality is excellent on interstates, but US-2 can be two-lane and winding. Watch for deer, especially at dawn/dusk. Rest areas every 30 miles on I-75.

• Family stop: Mackinac Island’s horse-drawn carriage tours
• Pet-friendly: Mackinac Bridge allows pets in vehicles, but ferry rules vary
• Fatigue: Stop at the Grayling rest area (mile marker 251) for a break