Plan on about 6 h 12 min of driving for the 291-mile (468 km) trip from Los Andes to Pelluhue, before any stops.
Full advisory: Chile. Advisory issued: Chile August 19, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Chile: “Driving in Chile is relatively safe.”
| Total distance | 291 mi (468 km) |
|---|---|
| Time at the wheel, no stops | 6 h 12 min |
| Main roads, in order | E-57 → L-30-K → 126 N → M-50-K |
| Regions on the route | Valparaíso, Región Metropolitana de Santiago, Libertador General Bernardo O'Higgins, Maule |
| Fuel estimate (car at 25 mpg) | about 11.6 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
On the road from Los Andes to Pelluhue
126 N (37 mi) and M-50-K (18 mi) carry about 19% of the 291 miles. It runs through 4 regions: Valparaíso, Región Metropolitana de Santiago, Libertador General Bernardo O'Higgins, Maule. Of the 9 stops listed below, 3 are within a mile of the road.
Los Andes to Pelluhue: the road sequence
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–1 | 1 | Valparaíso |
| E-57 | 1–5 | 4 | Valparaíso |
| connecting roads | 5–6 | 1 | Valparaíso |
| local roads | 6–42 | 36 | Valparaíso, Región Metropolitana de Santiago |
| connecting roads | 42–43 | 1 | Región Metropolitana de Santiago |
| local roads | 43–221 | 178 | Región Metropolitana de Santiago, Libertador General Bernardo O'Higgins, Maule |
| L-30-K | 221–225 | 4 | Maule |
| 126 N | 225–262 | 37 | Maule |
| local roads | 262–268 | 6 | Maule |
| connecting roads | 268–269 | 1 | Maule |
| M-50-K | 269–287 | 18 | Maule |
| local roads | 287–291 | 4 | Maule |
- Mile 15 of this route: Valparaíso → Región Metropolitana de Santiago (region line)
- Mile 85 of this route: Región Metropolitana de Santiago → Libertador General Bernardo O'Higgins (region line)
- Mile 155 of this route: Libertador General Bernardo O'Higgins → Maule (region line)
Where to stop on the way to Pelluhue
- Right off the route (under 1 mile): Basilica of Lourdes, Santiago (mile 48), Museo Nacional Aeronáutico y del Espacio (mile 52), Jardín botánico de la Universidad de Talca (mile 204)
- Nature and outdoors: Laguna Piedra Roja (mile 35), Jardín botánico de la Universidad de Talca (mile 204)
- Museums and history: Basílica del Salvador (mile 48), Basilica of Lourdes, Santiago (mile 48), Museo Nacional Aeronáutico y del Espacio (mile 52), Open Air Museum San Miguel (mile 52), Sagrario Cathedral (mile 103), O'Higginiano Historical Museum (mile 206)
Laguna Piedra Roja
Laguna Piedra Roja is an artificial lagoon in Chicureo, in the Colina commune of Chile's Santiago Metropolitan Region.
Basílica del Salvador
At Huérfanos and Almirante Barroso streets in Santiago's Barrio Brasil, the Basílica del Salvador is a neo-Gothic church designed by German architect Teodoro Burchard.
Basilica of Lourdes, Santiago
The Basilica of Lourdes is a church in Santiago, standing across from Quinta Normal Park.
Museo Nacional Aeronáutico y del Espacio
Chile's Museo Nacional Aeronáutico y del Espacio is a national museum dedicated to sharing the country's aviation heritage with visitors.
Open Air Museum San Miguel
More than sixty urban art murals and mosaics cover apartment walls, houses, benches and kiosks in Villa San Miguel, forming this open-air museum in the San Miguel commune, south of Santiago.
Sagrario Cathedral
Also known as Rancagua Cathedral, the Sagrario Cathedral is a Catholic church in Rancagua that has been declared a protected historic building.
Teatro Municipal de San Fernando
Teatro Municipal de San Fernando is a public theater in the commune of San Fernando, Colchagua Province, in Chile's Libertador General Bernardo O'Higgins Region.
Jardín botánico de la Universidad de Talca
Opened to the public in 2001, the University of Talca's 10-hectare botanical garden showcases plants from the Maule Region, Chile and around the world, including rare and threatened species.
O'Higginiano Historical Museum
Housed in the Casa de la Independencia in Talca, the O'Higginiano Historical Museum is an art museum that has operated under its current name since August 20, 1964.
Once you reach Pelluhue
Los Ruiles National Reserve
Los Ruiles National Reserve, in Cauquenes Province of the Maule Region, has two sections protecting enclaves of native forest home to several threatened and endangered species.
More drives to Pelluhue
- Pichilemu to Pelluhue
- Rancagua to Pelluhue
- Santiago, Chile to Pelluhue
- Viña del Mar to Pelluhue
- Valparaíso to Pelluhue
- Coquimbo to Pelluhue
From Los Andes to other places in Chile
- Los Andes to Reñaca
- Los Andes to El Colorado
- Los Andes to Valle Nevado
- Los Andes to Quintay
- Los Andes to Algarrobo
- Los Andes to Vicuña
Continue Your Adventure
Frequently asked questions
How long is the drive from Los Andes to Pelluhue?
About 6 h 12 min of driving without stops, over 291 miles.
What is the driving distance from Los Andes to Pelluhue?
About 291 miles (468 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
What does the U.S. travel advisory say about the Los Andes to Pelluhue drive?
The U.S. State Department rates Chile Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Los Andes to Pelluhue use?
In order: E-57, L-30-K, 126 N and M-50-K. The road-by-road table above shows the route miles for each one.
What are good stops between Los Andes and Pelluhue?
Closest to the road: Basilica of Lourdes, Santiago (basilica, mile 48, 0.4 mi from the route); Museo Nacional Aeronáutico y del Espacio (museum, mile 52, 0.5 mi from the route); Jardín botánico de la Universidad de Talca (botanical garden, mile 204, 0.2 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.