Locarno to Varenna: Alpine Road Trip Guide

The road from Locarno, Switzerland, to Varenna, Italy, winds through the heart of the Alps, crossing the border at the historic town of Camedo. The route is defined by sharp switchbacks and tunnels, including the famous Centovalli Railway path paralleling the drive. Since 1992, the Centovalli Bridge (Ponte di Verdasio) has stood as a concrete testimonial to the region's complex geography and the need for resilient infrastructure. The journey is a test of endurance and appreciation for Alpine engineering.

• Driving distance: ~190 km (120 mi)
• Estimated time: 4–5 hours without stops
• Key highways: A13 (Swiss), SS340 (Italian)

You'll leave Locarno via Via della Stazione, merging onto A13 toward the Italian border. The A13 narrows into the winding SS340 south of Domodossola. This single-carriageway road demands attention, especially in the rain.

• Border crossing: Camedo (Swiss customs; often no stop)
• Toll sections: No tolls in Switzerland (vignette required), but Italy's A26 (optional detour) has tolls €1.50–€5
• Fuel cost estimate: CHF 30–40 (Swiss) or €35–50 (Italian) for the full tank

Fuel efficiency tips: Using engine braking on descents saves fuel; the climb from Domodossola to the Simplon Pass area consumes more. Petrol stations are frequent in towns but scarce on mountain stretches. Fill up at Locarno or Domodossola.

For more tips, see how to find the best stops and hidden gems between cities.

Geographical shifts: The route leaves Swiss lake scenery (Lago Maggiore) for narrow valleys with waterfalls, then opens to Italian hills. The Centovalli ('Hundred Valleys') offers views of serpentine roads over ancient rivers.

• Key landscapes: Centovalli valley, Lake Maggiore views, Pre-Alpine foothills.
• UNESCO sites: Monte San Giorgio (25 km detour from Locarno) is a UNESCO World Heritage Site for its Middle Triassic fossils.

Local commerce: In Camedo, stop at the small market for locally-produced cheese and honey. Near Domodossola, artisan woodcarvers sell traditional crafts. Varenna's old town features linen boutiques and silk vendors.

• Must-buy: 'Biscotti della Nonna' (pistachio cookies) at Panetteria Varenna.
• Regional diner: Ristorante La Cascata in Malesco serves polenta and game.

Road quality: The Swiss A13 is well-maintained with clear markings. Italian SS340 has some rough patches but is generally safe. Night illumination is sparse on mountain sections; use high beams cautiously. Speed cameras are common in Italian villages.

• Safety tips: Avoid sudden braking on gravel sections; watch for livestock signs.
• Pet-friendly: Dogs are welcome at Parco della Punta di Campagnano (Laveno-Mombello) on Lake Maggiore.

Family spots: Minigolf in Domodossola and the Butterfly House in Varenna (temporary exhibitions year-round) engage children. Fatigue management: Rest at Autogrill in Ornavasso (Italian side) or at the picnic area in Re, Switzerland.

Hidden off-route: The abandoned village of Vocca, 3 minutes from SS340, features crumbling stone houses and a serene chapel. Another gem: the tiny hamlet of Cuzzago, known for its medieval washhouse.