Lexington to Red Wing Drive: Ultimate Road Trip Guide

This road trip from Lexington, Kentucky to Red Wing, Minnesota covers roughly 750 miles, crossing the Ohio River, the Corn Belt, and the Mississippi River Valley. The most efficient route follows I-75 north to Cincinnati, then I-74 west to Indianapolis, I-65 north to Chicago, I-94/90 west to Wisconsin, and finally US-61 north to Red Wing. Expect 11–12 hours of driving without stops, but the journey rewards those who linger.

Interstates are well-maintained. Construction common in summer. Take breaks every 2 hours. Family-friendly stops include the Children's Museum of Indianapolis and the Madison Zoo. Pet-friendly hotels abound; rest areas have pet walks.

• Fatigue tip: Nap zones at rest areas every 50 mi
• Family stop: Indianapolis (Oklahoma City I-65)
• Pet stop: Mississippi River Valley rest area, US-61

Planning fuel stops is straightforward. Gas stations are plentiful along interstates, but prices vary. Fill up in Kentucky before crossing into Illinois, where taxes are higher. Toll roads exist near Chicago (I-94/I-90) — have cash or an I-PASS.

• Estimated fuel cost: $80–$110 (sedan, 25 mpg)
• Best fuel stop: Effingham, IL (I-57/70 junction)
• Worst traffic: Chicago metro (avoid 4–7 PM)

Kentucky's rolling horse farms give way to Illinois flatlands, then Wisconsin's driftless region with dramatic bluffs. The Mississippi River near Red Wing is a highlight. For commerce, explore local farmers' markets and antique shops.

• Natural highlight: Starved Rock State Park, IL (off I-80)
• Hidden gem: Galena, IL (historic main street)
• Cultural stop: Frank Lloyd Wright's Taliesin, Spring Green, WI