Plan on about 9 h 32 min of driving for the 450-mile (724 km) trip from La Plata to Minas, Uruguay, before any stops. You cross from Argentina into Uruguay at about mile 201, at the Gualeguaychú–Fray Bentos bridge.
Full advisory: Argentina, Uruguay. Advisory issued: Argentina July 10, 2026; Uruguay July 28, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Argentina: “Drivers in Argentina tend to be aggressive, especially in Buenos Aires, and often ignore traffic regulations.”
- Uruguay: “Illumination, pavement markings, and road surfaces for secondary roads can be poor.”
| Distance | 450 mi (724 km) |
|---|---|
| Drive time without stops | 9 h 32 min |
| Main roads, in order | RN1 → AV1-N → RN9 → RP6 → RN12 → RN14 → RN136 |
| Border crossing | about mile 201, Argentina → Uruguay (the Gualeguaychú–Fray Bentos bridge) |
| Regions on the route | Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja |
| Fuel estimate (car at 25 mpg) | about 18.0 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Getting across the Argentina–Uruguay border
The route crosses at about mile 201, at the Gualeguaychú–Fray Bentos bridge, from Entre Ríos into Río Negro. Plan on two checks on each side: immigration for your passport and customs for the car.
| Entering Uruguay (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. |
|---|---|
| Driving in Uruguay | You can drive on your U.S. license. |
| Entering Argentina (U.S. citizens) | No visa needed for visits of 90 days or less. Passport: must be valid when you enter; leave a blank page for the entry and exit stamps. |
| Driving in Argentina | A valid U.S. license usually works; an International Driving Permit is recommended. |
| Rental car | Cross only if the rental company authorizes it in writing and gives you the papers for the border; ask before you book. |
Sources: U.S. State Department, Uruguay (updated August 13, 2026); U.S. State Department, Argentina (updated July 16, 2026). Checked October 10, 2026; rules change, so confirm before you go.
What the drive from La Plata to Minas is like
RN12 (47 mi) and RN9 (39 mi) carry about 19% of the 450 miles. The first 201 miles are in Argentina; the last 249 are in Uruguay. It runs through 9 regions: Buenos Aires, Ciudad de Buenos Aires, Entre Ríos, Río Negro, Soriano, Colonia, San José, Canelones, Lavalleja. Of the 9 stops listed below, 7 are within a mile of the road.
Which roads connect La Plata and Minas
| Road | Route miles (from–to) | Length, mi | Region |
|---|---|---|---|
| local roads | 0–3 | 3 | Buenos Aires |
| RN1 | 3–33 | 30 | Buenos Aires, Ciudad de Buenos Aires |
| local roads | 33–37 | 4 | Ciudad de Buenos Aires |
| AV1-N | 37–42 | 5 | Ciudad de Buenos Aires |
| connecting roads | 42–45 | 3 | Ciudad de Buenos Aires |
| RN9 | 45–84 | 39 | Buenos Aires |
| connecting roads | 84–85 | 1 | Buenos Aires |
| RP6 | 85–89 | 4 | Buenos Aires |
| RN12 | 89–136 | 47 | Buenos Aires, Entre Ríos |
| RN14 | 136–173 | 37 | Entre Ríos |
| local roads | 173–179 | 6 | Entre Ríos |
| RN136 | 179–198 | 19 | Entre Ríos |
| connecting roads | 198–201 | 3 | Entre Ríos |
| local roads | 201–298 | 97 | Río Negro, Soriano |
| connecting roads | 298–299 | 1 | Soriano |
| local roads | 299–335 | 36 | Colonia, San José |
| connecting roads | 335–338 | 3 | San José |
| local roads | 338–450 | 112 | San José, Canelones, Lavalleja |
- Mile 29 of this route: Buenos Aires → Ciudad de Buenos Aires (region line)
- Mile 45 of this route: Ciudad de Buenos Aires → Buenos Aires (region line)
- Mile 107 of this route: Buenos Aires → Entre Ríos (region line)
- Mile 201 of this route: Entre Ríos → Río Negro (international border)
- Mile 217 of this route: Río Negro → Soriano (region line)
- Mile 299 of this route: Soriano → Colonia (region line)
- Mile 316 of this route: Colonia → San José (region line)
- Mile 360 of this route: San José → Canelones (region line)
- Mile 426 of this route: Canelones → Lavalleja (region line)
Places worth a stop between La Plata and Minas
- Right off the route (under 1 mile): Buenos Aires Museum of Modern Art (mile 34), Illuminated Block (mile 35), Palais de Glace (mile 37), Temaikèn (mile 68), Cathedral of Mercedes (mile 219), Cathedral of San José de Mayo (mile 336), Cathedral of Our Lady of Guadalupe (mile 370)
- Museums and history: Buenos Aires Museum of Modern Art (mile 34), Illuminated Block (mile 35), Palais de Glace (mile 37), Gualeguaychú Cathedral (mile 178), Cathedral of Mercedes (mile 219), Cathedral of San José de Mayo (mile 336), Cathedral of Our Lady of Guadalupe (mile 370), Iglesia de Cristo Obrero y Nuestra Señora de Lourdes (mile 406)
- With kids: Temaikèn (mile 68)
Buenos Aires Museum of Modern Art
Known locally as the Museo de Arte Moderno de Buenos Aires, this modern art museum is in the San Telmo district of Buenos Aires.
Illuminated Block
The Illuminated Block (Manzana de las Luces) is a historical landmark in the Monserrat neighborhood of Buenos Aires, Argentina.
Palais de Glace
At 1430 Posadas Street in Recoleta, Buenos Aires, the Palais de Glace is a Belle Époque building modeled on the Palais des Glaces in Paris.
Temaikèn
Temaikèn is a zoo in Belén de Escobar, outside Buenos Aires, and the only zoo in Argentina accredited by the Association of Zoos and Aquariums.
Gualeguaychú Cathedral
St. Joseph's Cathedral, also called Gualeguaychú Cathedral, serves as the cathedral church of the Roman Catholic Diocese of Gualeguaychú in Argentina.
Cathedral of Mercedes
Dedicated to Our Lady of Mercy, this cathedral is the main Catholic church of Mercedes, Uruguay, and has been the seat of the Diocese of Mercedes since 1960.
Cathedral of San José de Mayo
The main Catholic church of San José de Mayo, the Cathedral Basilica of St. Joseph has been the diocesan seat since 1955, a minor basilica since 1957 and Uruguay's national shrine of Saint Joseph.
Cathedral of Our Lady of Guadalupe
Construction of Canelones' Cathedral of Our Lady of Guadalupe began in 1816; the church became a cathedral in 1961 and Uruguay's national shrine of Our Lady of Guadalupe in 2020.
Iglesia de Cristo Obrero y Nuestra Señora de Lourdes
Wavy brick walls and a rippling brick roof define this church in Estación Atlántida, along with an openwork brick bell tower and a baptistery set underground. Engineer Eladio Dieste designed it, and it opened in 1960.
When you get to Minas
Cathedral of Minas
Minas's main Catholic church, the Cathedral of the Immaculate Conception served as the seat of the Diocese of Minas from 1960 to 2020.
Teatro Lavalleja
Teatro Lavalleja is a theater complex in the city of Minas, in the Lavalleja department of Uruguay.
More drives to Minas
More drives from La Plata
- La Plata to Tigre
- La Plata to Luján
- La Plata to San Antonio de Areco
- La Plata to Arrecifes
- La Plata to Pergamino
- La Plata to Martínez
Continue Your Adventure
Frequently asked questions
How long does it take to drive from La Plata to Minas, Uruguay?
About 9 h 32 min of driving without stops, over 450 miles.
What is the driving distance from La Plata to Minas, Uruguay?
About 450 miles (724 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Where does the La Plata to Minas drive cross the border?
At about mile 201, from Argentina into Uruguay, at the Gualeguaychú–Fray Bentos bridge.
What do U.S. citizens need to drive from La Plata into Uruguay?
No visa needed for visits of 90 days or less. Passport: must be valid for 6 months beyond your arrival date. You can drive on your U.S. license. (U.S. State Department, updated August 13, 2026.)
Is it safe to drive from La Plata to Minas, Uruguay?
The U.S. State Department rates Argentina Level 1: Exercise Normal Precautions; Uruguay Level 2: Exercise Increased Caution. Read the full advisory before you go.
Which highways go from La Plata to Minas?
In order: RN1, AV1-N, RN9, RP6, RN12, RN14 and RN136. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from La Plata to Minas?
Closest to the road: Buenos Aires Museum of Modern Art (museum of modern art, mile 34, 0.4 mi from the route); Palais de Glace (museum, mile 37, 0.5 mi from the route); Cathedral of Our Lady of Guadalupe (cathedral, mile 370, 0.1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.