The Wayro route from Itu to Barretos is 222 miles (357 km), about 4 h 24 min of driving without stops.
- Level 4: Do Not Travel in Brazil: informal housing developments (favelas, vilas, comunidades or conglomerados).
Full advisory: Brazil. Advisory issued: Brazil August 31, 2026; checked October 10, 2026.
On the roads, the State Department says:
- Brazil: “Drivers must have their daytime running lights on during the day and headlights on at night on Federal Highways.”
| Distance by road | 222 mi (357 km) |
|---|---|
| Driving time, no stops | 4 h 24 min |
| Main roads, in order | SP-075 → SP-308 → SPI-162 → SP-127 → SP-310 → SP-326 |
| States on the route | São Paulo |
| Fuel estimate (car at 25 mpg) | about 8.9 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
What the drive from Itu to Barretos is like
SP-326 (79 mi) and SP-310 (75 mi) carry about 69% of the 222 miles. None of the 8 stops below is right on the road, so plan each as a short side trip.
Road-by-road breakdown: Itu to Barretos
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–2 | 2 | São Paulo |
| SP-075 | 2–6 | 4 | São Paulo |
| SP-308 | 6–44 | 38 | São Paulo |
| SPI-162 | 44–48 | 4 | São Paulo |
| connecting roads | 48–49 | 1 | São Paulo |
| SP-127 | 49–65 | 16 | São Paulo |
| SP-310 | 65–140 | 75 | São Paulo |
| SP-326 | 140–219 | 79 | São Paulo |
| local roads | 219–222 | 3 | São Paulo |
Where to stop on the way to Barretos
- Museums and history: Museu Histórico e Pedagógico Prudente de Moraes (mile 45), Museu de Minerais e Rochas Heinz Ebert (mile 67), St. Charles Borromeo Cathedral, São Carlos (mile 103), Museum of Science Professor Mario Tolentino (mile 103), Casa da Cultura Luís Antonio Martinez Corrêa (mile 127), Museu Histórico de Jaboticabal (mile 169), Our Lady of Carmel Cathedral, Jaboticabal (mile 170), André Matarazzo Museum of Arms, Vehicles and Machines Eduardo (mile 193)
- With kids: Museum of Science Professor Mario Tolentino (mile 103)
Museu Histórico e Pedagógico Prudente de Moraes
Piracicaba's Prudente de Moraes museum fills the 19th-century home where Brazil's first civilian president lived until his death in 1902, with his belongings, local art and an exhibit on the city's history.
Museu de Minerais e Rochas Heinz Ebert
The Heinz Ebert Museum of Minerals and Rocks is located on the Unesp campus in Rio Claro, in São Paulo state, inside the Department of Petrology and Metallogeny building.
St. Charles Borromeo Cathedral, São Carlos
St. Charles Borromeo Cathedral is a Catholic church on Dom José Marcondes Homem de Melo Square in the city of São Carlos, São Paulo state.
Museum of Science Professor Mario Tolentino
Opened by the city of São Carlos in 2012, this science museum offers interactive exhibits and experiments in science, technology and art, named for professor and historian Mario Tolentino.
Casa da Cultura Luís Antonio Martinez Corrêa
A small theater, rooms for cultural workshops and historical collections from documents to artworks fill Araraquara's Casa da Cultura.
Museu Histórico de Jaboticabal
Run by the city of Jaboticabal, the Museu Histórico de Jaboticabal Aloísio de Almeida was created by law in 1965 and opened to the public on July 16, 1979, to preserve the town's historic and artistic heritage.
Our Lady of Carmel Cathedral, Jaboticabal
Jaboticabal's Our Lady of Carmel Cathedral stands on Joaquim Batista Square, the city's zero point. It serves as seat of the Catholic Diocese of Jaboticabal and became a parish in 1898.
André Matarazzo Museum of Arms, Vehicles and Machines Eduardo
Known locally as the Museu do Automóvel, Bebedouro's private museum grew from Eduardo André Matarazzo's collection of vintage vehicles and also shows retired airliners outdoors, including a DC-3 and a Vickers Viscount.
Once you reach Barretos
Museu Ruy Menezes
In Barretos, São Paulo, the Ruy Menezes Historical, Artistic and Folkloric Museum safeguards the city's memory through documents and objects from local history.
More drives to Barretos
- Araraquara to Barretos
- São Carlos to Barretos
- Limeira to Barretos
- Piracicaba to Barretos
- Poços de Caldas to Barretos
- Campinas to Barretos
From Itu to other places in Brazil
Frequently asked questions
How long does it take to drive from Itu to Barretos?
About 4 h 24 min of driving without stops, over 222 miles.
How far is Barretos from Itu by car?
About 222 miles (357 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Is it safe to drive from Itu to Barretos?
The U.S. State Department rates Brazil Level 2: Exercise Increased Caution. Read the full advisory before you go.
What roads does the drive from Itu to Barretos use?
In order: SP-075, SP-308, SPI-162, SP-127, SP-310 and SP-326. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Itu to Barretos?
Closest to the road: Museum of Science Professor Mario Tolentino (museum, mile 103, 2 mi from the route); Casa da Cultura Luís Antonio Martinez Corrêa (historic site, mile 127, 2 mi from the route); Museu Histórico de Jaboticabal (museum, mile 169, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on October 10, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.