The Wayro route from Guanajuato to Zacatelco is 289 miles (465 km), about 4 h 49 min of driving without stops.
| Distance | 289 mi (465 km) |
|---|---|
| Driving time, no stops | 4 h 49 min |
| Main roads, in order | MEX-110 → MEX-45 → MEX-45D → MEX-47D → MEX-57D → MEX-M40D → MEX-117D → MEX-119 |
| Mexican states on the route | Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Tlaxcala (Level 2), Puebla (Level 2) |
| Toll roads | MEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-M40D, MEX-117D |
| Fuel estimate (car at 25 mpg) | about 11.6 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Guanajuato to Zacatelco is like
MEX-M40D (104 mi) and MEX-47D (52 mi) carry about 54% of the 289 miles. MEX-45D, MEX-47D, MEX-57D, MEX-M40D, MEX-117D are toll highways (cuota); MEX-110, MEX-45, MEX-119 are free federal roads (libre). It runs through 6 states: Guanajuato, Querétaro, State of Mexico, Hidalgo, Tlaxcala, Puebla. Of the 8 stops listed below, 1 are within a mile of the road.
The route from Guanajuato to Zacatelco, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–1 | 1 | Guanajuato |
| MEX-110 | 1–7 | 6 | Guanajuato |
| local roads | 7–13 | 6 | Guanajuato |
| MEX-45 | 13–23 | 10 | Guanajuato |
| connecting roads | 23–24 | 1 | Guanajuato |
| MEX-45D | 24–75 | 51 | Guanajuato |
| connecting roads | 75–76 | 1 | Guanajuato |
| MEX-47D | 76–128 | 52 | Guanajuato, Querétaro |
| MEX-57D | 128–163 | 35 | Querétaro, State of Mexico |
| connecting roads | 163–164 | 1 | Hidalgo |
| MEX-M40D | 164–268 | 104 | Hidalgo, State of Mexico, Tlaxcala, Puebla |
| MEX-117D | 268–283 | 15 | Puebla, Tlaxcala |
| MEX-119 | 283–288 | 5 | Tlaxcala |
| local roads | 288–289 | 1 | Tlaxcala |
- Mile 88 of this route: Guanajuato → Querétaro (state line)
- Mile 130 of this route: Querétaro → State of Mexico (state line)
- Mile 163 of this route: State of Mexico → Hidalgo (state line)
- Mile 193 of this route: Hidalgo → State of Mexico (state line)
- Mile 207 of this route: State of Mexico → Hidalgo (state line)
- Mile 224 of this route: Hidalgo → State of Mexico (state line)
- Mile 236 of this route: State of Mexico → Hidalgo (state line)
- Mile 244 of this route: Hidalgo → Tlaxcala (state line)
- Mile 267 of this route: Tlaxcala → Puebla (state line)
- Mile 270 of this route: Puebla → Tlaxcala (state line)
Stops between Guanajuato and Zacatelco
- Right off the route (under 1 mile): Tula National Park (mile 176)
- Nature and outdoors: Cerro de las Campanas (mile 87), El Cimatario National Park (mile 93), Tula National Park (mile 176)
- Museums and history: Celaya Cathedral (mile 63), Museo Arqueológico de Apaxco (mile 191), Tlaxcala Cathedral (mile 280)
Celaya Cathedral
Celaya's main Catholic church, the Immaculate Conception Cathedral, occupies the space of a former chapel that was annexed to the neighboring Temple of St. Francis.
Cerro de las Campanas
Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.
El Cimatario National Park
El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.
Atlantean figures
Crowning the main pyramid at the Tula archaeological zone, these basalt sculptures of Toltec warriors stand more than four meters tall in what was once the Toltec capital; the nearby Wall of Snakes shows carved serpents devouring skeletons.
Tula National Park
This park protects the ruins of Tula, ancient capital of the Toltecs. Walk up to the main pyramid to stand beside the Atlantes, basalt warrior figures more than four meters tall, and look for the Coatepantli wall's reliefs of snakes devouring skeletons.
Museo Arqueológico de Apaxco
Founded in 1985, the Museo Arqueológico de Apaxco sits across from the parish church of San Francisco de Asís and beside the town hall in Apaxco, State of Mexico.
Aqueduct of Padre Tembleque
Built by Franciscan friar Francisco de Tembleque between 1554 and 1572, this 16th-century water system runs more than 48 km between Zempoala and Otumba. Its tallest arcade at Tepeyahualco reaches almost 40 meters, and UNESCO listed it in 2015.
Tlaxcala Cathedral
Part of a 16th-century Franciscan complex among the earliest in the Americas, Tlaxcala's cathedral is famous for its carved Mudéjar-style wooden ceiling. Look for the freestanding bell tower and the stone font where Tlaxcalan lords were baptized.
When you get to Zacatelco
Laguna de Acomulco
A quiet lagoon in the state of Tlaxcala, Laguna de Acomulco is surrounded by vegetation and rural scenery and works well for a short walk, landscape photos or a calm break in nature.
Parque ecológico Los Ladrillos
Opened on April 2, 2015, Los Ladrillos Ecological Park is a nature reserve in the municipality of Zacatelco, in Tlaxcala.
More drives to Zacatelco
- Huamantla to Zacatelco
- Cuautla to Zacatelco
- Pachuca to Zacatelco
- Tulancingo to Zacatelco
- Tepotzotlán to Zacatelco
- Cuernavaca to Zacatelco
From Guanajuato to other places in Mexico
- Guanajuato to Amatitán
- Guanajuato to Tequila
- Guanajuato to Jerez, Zacatecas
- Guanajuato to Sombrerete
- Guanajuato to El Rosario, Sinaloa
- Guanajuato to San Ignacio, Sinaloa
Continue Your Adventure
Frequently asked questions
How long is the drive from Guanajuato to Zacatelco?
About 4 h 49 min of driving without stops, over 289 miles.
How far is Zacatelco from Guanajuato by car?
About 289 miles (465 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Guanajuato to Zacatelco?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Guanajuato to Zacatelco?
The U.S. State Department rates Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Guanajuato to Zacatelco use?
In order: MEX-110, MEX-45, MEX-45D, MEX-47D, MEX-57D, MEX-M40D, MEX-117D and MEX-119. The road-by-road table above shows the route miles and states for each one.
What are good stops between Guanajuato and Zacatelco?
Closest to the road: Atlantean figures (atlantean figures, mile 175, 1 mi from the route); Tula National Park (National Park of Mexico, mile 176, 1 mi from the route); Tlaxcala Cathedral (catholic cathedral, mile 280, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.