Guanajuato to Oaxtepec Road Trip: Route, Stops & Safety

By admin, 3 October, 2026

The Wayro route from Guanajuato to Oaxtepec is 281 miles (452 km), about 4 h 50 min of driving without stops.

U.S. State Department travel advisory: Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Mexico City — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Oaxtepec. Check the full advisory for this state before you go.
El Cimatario National ParkTemplo y exconvento de San FranciscoMuseo Nacional de HistoriaLeon Trotsky House MuseumMuseo Universitario de Ciencias y ArtesSix Flags MéxicoZoológico Los CoyotesArchivo Diseño y ArquitecturaGuanajuatoOaxtepec
Route from Guanajuato to Oaxtepec with the 8 stops listed below (blue dots).
Distance281 mi (452 km)
Driving time, no stops4 h 50 min
Main roads, in orderMEX-110 → MEX-45 → MEX-45D → MEX-47D → MEX-57D → MEX-57 → Periférico → MEX-95D → MEX-160D
Mexican states on the routeGuanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Mexico City (Level 2), Morelos (Level 3)
Toll roadsMEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-95D, MEX-115D, MEX-160D
Fuel estimate (car at 25 mpg)about 11.2 gal; actual use varies by vehicle and traffic
Stops listed below8

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Guanajuato to Oaxtepec is like

MEX-57D (73 mi) and MEX-47D (52 mi) carry about 44% of the 281 miles. MEX-45D, MEX-47D, MEX-57D, MEX-95D, MEX-160D are toll highways (cuota); MEX-110, MEX-45, MEX-57 are free federal roads (libre). It runs through 6 states: Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos. Of the 8 stops listed below, 3 are within a mile of the road.

The route from Guanajuato to Oaxtepec, road by road

RoadRoute miles (from–to)Length, miState
local roads0–11Guanajuato
MEX-1101–76Guanajuato
local roads7–136Guanajuato
MEX-4513–2310Guanajuato
connecting roads23–241Guanajuato
MEX-45D24–7551Guanajuato
connecting roads75–761Guanajuato
MEX-47D76–12852Guanajuato, Querétaro
MEX-57D128–20173Querétaro, State of Mexico, Hidalgo
MEX-57201–2109State of Mexico
Periférico210–22919State of Mexico, Mexico City
connecting roads229–2312Mexico City
MEX-95D231–26332Mexico City, Morelos
MEX-160D263–27916Morelos
local roads279–2812Morelos
  • Mile 88 of this route: Guanajuato → Querétaro (state line)
  • Mile 130 of this route: Querétaro → State of Mexico (state line)
  • Mile 163 of this route: State of Mexico → Hidalgo (state line)
  • Mile 183 of this route: Hidalgo → State of Mexico (state line)
  • Mile 215 of this route: State of Mexico → Mexico City (state line)
  • Mile 248 of this route: Mexico City → Morelos (state line)

Stops between Guanajuato and Oaxtepec

  • Right off the route (under 1 mile): Templo y exconvento de San Francisco (mile 176), Museo Nacional de Historia (mile 216), Six Flags México (mile 226)
  • Nature and outdoors: El Cimatario National Park (mile 93)
  • Museums and history: Museo Nacional de Historia (mile 216), Leon Trotsky House Museum (mile 220), Museo Universitario de Ciencias y Artes (mile 222), Archivo Diseño y Arquitectura (mile 237)
  • With kids: Six Flags México (mile 226), Zoológico Los Coyotes (mile 229)

El Cimatario National Park

Mile 93 · National Park of Mexico · 9 mi from the route · side trip; actual detour depends on access roads

El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.

Templo y exconvento de San Francisco

Mile 176 · Convent · 0.6 mi from the route

The Templo y Exconvento de San Francisco is a church and former convent located in the city of Tepeji del Río, in the Mexican state of Hidalgo.

Museo Nacional de Historia

Mile 216 · National museum · 0.9 mi from the route

Inside Chapultepec Castle in Chapultepec Park, the National Museum of History (Museo Nacional de Historia) covers Mexico's past as one of the country's national museums.

Leon Trotsky House Museum

Mile 220 · Historic house museum · 2 mi from the route · side trip; actual detour depends on access roads

In Coyoacán, the house museum honoring Leon Trotsky, officially the Instituto del Derecho de Asilo - Museo Casa de León Trotsky, also works to promote political asylum.

Museo Universitario de Ciencias y Artes

Mile 222 · Museum · 1 mi from the route

MUCA, the Museo Universitario de Ciencias y Artes, is a university venue that promotes multidisciplinary exhibitions and also offers academic and outreach activities.

Six Flags México

Mile 226 · Amusement park · 0.7 mi from the route

Six Flags México is an amusement park operated by Six Flags on the southern edge of Mexico City, in the forested Tlalpan borough.

Zoológico Los Coyotes

Mile 229 · Zoo · 3 mi from the route · side trip; actual detour depends on access roads

Opened on February 2, 1999, Los Coyotes is Mexico City's third zoo, created to complement the capital's other zoos.

Archivo Diseño y Arquitectura

Mile 237 · Museum · 2 mi from the route

Founded in 2012 by architect Fernando Romero and Soumaya Slim, Archivo Diseño y Arquitectura in Mexico City exhibits and studies design, with more than 1,500 objects and Enrique del Moral's personal library.

When you get to Oaxtepec

Former convent of Saint Dominic de Guzmán

Convent · in Oaxtepec

In Oaxtepec, the Exconvento de Santo Domingo de Guzmán is among the first convents the Dominicans built in Mexico, and its walls preserve extensive fresco painting from the colonial era.

Templo y Exconvento de San Juan Bautista de Tlayacapan

Convent · in Oaxtepec

Augustinian friars began this fortress-like church and monastery in the 16th century. Part of the UNESCO-listed group of monasteries on the slopes of Popocatépetl, its former cloister now holds a museum with 17th-century murals and religious art.

More drives to Oaxtepec

From Guanajuato to other places in Mexico

Frequently asked questions

How long is the drive from Guanajuato to Oaxtepec?

About 4 h 50 min of driving without stops, over 281 miles.

How far is Oaxtepec from Guanajuato by car?

About 281 miles (452 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Guanajuato to Oaxtepec?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Guanajuato to Oaxtepec?

The U.S. State Department rates Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Mexico City Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Guanajuato to Oaxtepec use?

In order: MEX-110, MEX-45, MEX-45D, MEX-47D, MEX-57D, MEX-57, Periférico, MEX-95D and MEX-160D. The road-by-road table above shows the route miles and states for each one.

What are good stops between Guanajuato and Oaxtepec?

Closest to the road: Templo y exconvento de San Francisco (convent, mile 176, 0.6 mi from the route); Museo Nacional de Historia (National museum, mile 216, 0.9 mi from the route); Six Flags México (amusement park, mile 226, 0.7 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.