The Wayro route from Guadalupe, Zacatecas to Zacualpan de Amilpas is 442 miles (711 km), about 7 h 56 min of driving without stops.
| Distance | 442 mi (711 km) |
|---|---|
| Driving time, no stops | 7 h 56 min |
| Main roads, in order | MEX-45D → MEX-45 → MEX-47D → MEX-57D → MEX-5D → MEX-115 |
| Mexican states on the route | Zacatecas (Level 4), Aguascalientes (Level 2), Jalisco (Level 3), Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Morelos (Level 3) |
| Toll roads | MEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-5D |
| Fuel estimate (car at 25 mpg) | about 17.7 gal; actual use varies by vehicle and traffic |
| Stops listed below | 9 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Guadalupe, Zacatecas to Zacualpan de Amilpas is like
MEX-45D (163 mi) and MEX-45 (58 mi) carry about 50% of the 442 miles. MEX-45D, MEX-47D, MEX-57D, MEX-5D are toll highways (cuota); MEX-45, MEX-115 are free federal roads (libre). It runs through 8 states: Zacatecas, Aguascalientes, Jalisco, Guanajuato, Querétaro, State of Mexico, Hidalgo, Morelos. Of the 9 stops listed below, 3 are within a mile of the road.
The route from Guadalupe, Zacatecas to Zacualpan de Amilpas, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | Zacatecas |
| MEX-45D | 4–25 | 21 | Zacatecas |
| MEX-45 | 25–53 | 28 | Zacatecas, Aguascalientes |
| local roads | 53–57 | 4 | Aguascalientes |
| MEX-45 | 57–87 | 30 | Aguascalientes, Jalisco |
| MEX-45D | 87–229 | 142 | Jalisco, Guanajuato |
| MEX-47D | 229–281 | 52 | Guanajuato, Querétaro |
| MEX-57D | 281–339 | 58 | Querétaro, State of Mexico, Hidalgo |
| MEX-5D | 339–393 | 54 | State of Mexico |
| connecting roads | 393–394 | 1 | State of Mexico |
| MEX-115 | 394–414 | 20 | State of Mexico |
| local roads | 414–442 | 28 | State of Mexico, Morelos |
- Mile 30 of this route: Zacatecas → Aguascalientes (state line)
- Mile 83 of this route: Aguascalientes → Jalisco (state line)
- Mile 132 of this route: Jalisco → Guanajuato (state line)
- Mile 241 of this route: Guanajuato → Querétaro (state line)
- Mile 283 of this route: Querétaro → State of Mexico (state line)
- Mile 316 of this route: State of Mexico → Hidalgo (state line)
- Mile 336 of this route: Hidalgo → State of Mexico (state line)
- Mile 423 of this route: State of Mexico → Morelos (state line)
Stops between Guadalupe, Zacatecas and Zacualpan de Amilpas
- Right off the route (under 1 mile): Museo Espacio, Aguascalientes (mile 67), Templo y exconvento de San Francisco (mile 329), Sacromonte National Park (mile 408)
- Nature and outdoors: Cerro de las Campanas (mile 240), El Cimatario National Park (mile 245), Sacromonte National Park (mile 408)
- Museums and history: Museo de la Insurgencia (mile 48), Museo Espacio, Aguascalientes (mile 67), Luis Barragán House and Studio (mile 370)
Museo de la Insurgencia
Set in a 17th-century estate, the Museo de la Insurgencia opened in 1964 to tell the story of Mexico's independence movement. One hall shows farm, mining and textile tools from hacienda work; another displays everyday objects from past eras.
Museo Espacio, Aguascalientes
Inside the Tres Centurias complex at Aguascalientes' old train station, Museo Espacio is a contemporary art museum, so a visit pairs current work with a look at the city's railroad buildings.
Cerro de las Campanas
Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.
El Cimatario National Park
El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.
Templo y exconvento de San Francisco
The Templo y Exconvento de San Francisco is a church and former convent located in the city of Tepeji del Río, in the Mexican state of Hidalgo.
Historic center of Mexico City
Built by the Spanish in the 16th century on the ruins of Tenochtitlan, Mexico City's Centro Histórico holds the Metropolitan Cathedral, the excavated Aztec Templo Mayor and the Palacio de Bellas Artes. UNESCO added it to the World Heritage List in 1987.
Luis Barragán House and Studio
Luis Barragán built his own house and studio in Mexico City in 1948, blending modern design with Mexican vernacular touches. The concrete house and its private garden joined UNESCO's World Heritage List in 2004.
Guerrero Chimalli
Rising 60 meters beside Bordo de Xochiaca Avenue in Chimalhuacán, this steel sculpture by Sebastián depicts an Indigenous warrior holding a shield (chimalli) and a mace.
Sacromonte National Park
Sacromonte National Park is a national park and protected area in the State of Mexico, established in 1952 and covering roughly 0.44 square kilometers.
More drives to Zacualpan de Amilpas
- Puebla to Zacualpan de Amilpas
- Cuernavaca to Zacualpan de Amilpas
- Zacatelco to Zacualpan de Amilpas
- Mexico City to Zacualpan de Amilpas
- Chiautempan to Zacualpan de Amilpas
- Apizaco to Zacualpan de Amilpas
From Guadalupe, Zacatecas to other places in Mexico
- Guadalupe, Zacatecas to San Juan de los Lagos
- Guadalupe, Zacatecas to Temacapulín
- Guadalupe, Zacatecas to Tepatitlán
- Guadalupe, Zacatecas to Amatitán
- Guadalupe, Zacatecas to Ajijic
- Guadalupe, Zacatecas to Tequila
Continue Your Adventure
Frequently asked questions
How long is the drive from Guadalupe, Zacatecas to Zacualpan de Amilpas?
About 7 h 56 min of driving without stops, over 442 miles.
How far is Zacualpan de Amilpas from Guadalupe, Zacatecas by car?
About 442 miles (711 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Guadalupe, Zacatecas to Zacualpan de Amilpas?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Guadalupe, Zacatecas to Zacualpan de Amilpas?
The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Guadalupe, Zacatecas to Zacualpan de Amilpas use?
In order: MEX-45D, MEX-45, MEX-47D, MEX-57D, MEX-5D and MEX-115. The road-by-road table above shows the route miles and states for each one.
What are good stops between Guadalupe, Zacatecas and Zacualpan de Amilpas?
Closest to the road: Museo Espacio, Aguascalientes (art museum, mile 67, 0.8 mi from the route); Templo y exconvento de San Francisco (convent, mile 329, 0.6 mi from the route); Sacromonte National Park (National Park of Mexico, mile 408, 0.3 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.