Guadalupe, Zacatecas to Ocuituco Road Trip: Stops & Tolls

By admin, 3 October, 2026

The Wayro route from Guadalupe, Zacatecas to Ocuituco is 432 miles (696 km), about 7 h 39 min of driving without stops.

U.S. State Department travel advisory: Zacatecas — Level 4, Do Not Travel; Aguascalientes — Level 2, Exercise Increased Caution; Jalisco — Level 3, Reconsider Travel; Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Ocuituco. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Museo de la InsurgenciaMuseo EscarcegaCerro de las CampanasEl Cimatario National ParkTemplo y exconvento de San FranciscoSacred Heart of Jesus Cathedral, EcatepecEl Tepeyac National ParkHistoric center of Mexico CitySacromonte National ParkGuadalupe, ZacatecasOcuituco
Route from Guadalupe, Zacatecas to Ocuituco with the 9 stops listed below (blue dots).
Distance432 mi (696 km)
Driving time, no stops7 h 39 min
Main roads, in orderMEX-45D → MEX-45 → MEX-47D → MEX-57D → MEX-5D → MEX-115
Mexican states on the routeZacatecas (Level 4), Aguascalientes (Level 2), Jalisco (Level 3), Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Morelos (Level 3)
Toll roadsMEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-5D
Fuel estimate (car at 25 mpg)about 17.3 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Guadalupe, Zacatecas to Ocuituco is like

MEX-45D (163 mi) and MEX-45 (58 mi) carry about 51% of the 432 miles. MEX-45D, MEX-47D, MEX-57D, MEX-5D are toll highways (cuota); MEX-45, MEX-115 are free federal roads (libre). It runs through 8 states: Zacatecas, Aguascalientes, Jalisco, Guanajuato, Querétaro, State of Mexico, Hidalgo, Morelos. Of the 9 stops listed below, 4 are within a mile of the road.

The route from Guadalupe, Zacatecas to Ocuituco, road by road

RoadRoute miles (from–to)Length, miState
local roads0–44Zacatecas
MEX-45D4–2521Zacatecas
MEX-4525–5328Zacatecas, Aguascalientes
local roads53–574Aguascalientes
MEX-4557–8730Aguascalientes, Jalisco
MEX-45D87–229142Jalisco, Guanajuato
MEX-47D229–28152Guanajuato, Querétaro
MEX-57D281–33958Querétaro, State of Mexico, Hidalgo
MEX-5D339–39354State of Mexico
connecting roads393–3941State of Mexico
MEX-115394–41420State of Mexico
local roads414–43218State of Mexico, Morelos
  • Mile 30 of this route: Zacatecas → Aguascalientes (state line)
  • Mile 83 of this route: Aguascalientes → Jalisco (state line)
  • Mile 132 of this route: Jalisco → Guanajuato (state line)
  • Mile 241 of this route: Guanajuato → Querétaro (state line)
  • Mile 283 of this route: Querétaro → State of Mexico (state line)
  • Mile 316 of this route: State of Mexico → Hidalgo (state line)
  • Mile 336 of this route: Hidalgo → State of Mexico (state line)
  • Mile 423 of this route: State of Mexico → Morelos (state line)

Stops between Guadalupe, Zacatecas and Ocuituco

  • Right off the route (under 1 mile): Museo Escarcega (mile 68), Templo y exconvento de San Francisco (mile 329), Sacred Heart of Jesus Cathedral, Ecatepec (mile 360), Sacromonte National Park (mile 408)
  • Nature and outdoors: Cerro de las Campanas (mile 240), El Cimatario National Park (mile 245), El Tepeyac National Park (mile 368), Sacromonte National Park (mile 408)
  • Museums and history: Museo de la Insurgencia (mile 48), Museo Escarcega (mile 68), Sacred Heart of Jesus Cathedral, Ecatepec (mile 360)

Museo de la Insurgencia

Mile 48 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Set in a 17th-century estate, the Museo de la Insurgencia opened in 1964 to tell the story of Mexico's independence movement. One hall shows farm, mining and textile tools from hacienda work; another displays everyday objects from past eras.

Museo Escarcega

Mile 68 · Art museum · 0.6 mi from the route

Eduardo Escárcega Rangel created this museum in the city of Aguascalientes to show his personal collection of paintings and prints by local, national and international artists.

Cerro de las Campanas

Mile 240 · National Park of Mexico · 12 mi from the route · side trip; actual detour depends on access roads

Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.

El Cimatario National Park

Mile 245 · National Park of Mexico · 9 mi from the route · side trip; actual detour depends on access roads

El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.

Templo y exconvento de San Francisco

Mile 329 · Convent · 0.6 mi from the route

The Templo y Exconvento de San Francisco is a church and former convent located in the city of Tepeji del Río, in the Mexican state of Hidalgo.

Sacred Heart of Jesus Cathedral, Ecatepec

Mile 360 · Cathedral · 0.7 mi from the route

The Sacred Heart of Jesus Cathedral, also called Ecatepec Cathedral, is the main Catholic church and seat of the Diocese of Ecatepec in Mexico, dedicated to the Sacred Heart of Jesus.

El Tepeyac National Park

Mile 368 · National Park of Mexico · 6 mi from the route · side trip; actual detour depends on access roads

Decreed in 1937 on reforested slopes of the Sierra de Guadalupe, including Cerro del Tepeyac, this national park was created for rest and recreation, with views toward Mexico City and the old Lake Texcoco plain.

Historic center of Mexico City

Mile 370 · Old town · 8 mi from the route · side trip; actual detour depends on access roads

Built by the Spanish in the 16th century on the ruins of Tenochtitlan, Mexico City's Centro Histórico holds the Metropolitan Cathedral, the excavated Aztec Templo Mayor and the Palacio de Bellas Artes. UNESCO added it to the World Heritage List in 1987.

Sacromonte National Park

Mile 408 · National Park of Mexico · 0.3 mi from the route

Sacromonte National Park is a national park and protected area in the State of Mexico, established in 1952 and covering roughly 0.44 square kilometers.

When you get to Ocuituco

Convento de Santiago Apóstol

Convent · in Ocuituco

In the town of Ocuituco, the Temple and Ex-convent of Santiago Apóstol (Templo y Exconvento de Santiago Apóstol) belongs to the UNESCO-listed group of 16th-century monasteries on the slopes of Popocatépetl, inscribed in 1994.

Convento de San Juan Bautista

Convent · in Ocuituco

This convent in Tetela del Volcán, known for its carved wooden sacristy and light-filled cloister walks, was cleaned of soot left from its use as a barracks during the Mexican Revolution in a conservation project completed in 2009.

More drives to Ocuituco

From Guadalupe, Zacatecas to other places in Mexico

Frequently asked questions

How long is the drive from Guadalupe, Zacatecas to Ocuituco?

About 7 h 39 min of driving without stops, over 432 miles.

How far is Ocuituco from Guadalupe, Zacatecas by car?

About 432 miles (696 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Guadalupe, Zacatecas to Ocuituco?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Guadalupe, Zacatecas to Ocuituco?

The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Guadalupe, Zacatecas to Ocuituco use?

In order: MEX-45D, MEX-45, MEX-47D, MEX-57D, MEX-5D and MEX-115. The road-by-road table above shows the route miles and states for each one.

What are good stops between Guadalupe, Zacatecas and Ocuituco?

Closest to the road: Museo Escarcega (art museum, mile 68, 0.6 mi from the route); Templo y exconvento de San Francisco (convent, mile 329, 0.6 mi from the route); Sacromonte National Park (National Park of Mexico, mile 408, 0.3 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.