Guadalupe, Zacatecas to Oaxtepec Road Trip: Stops & Tolls

By admin, 3 October, 2026

The Wayro route from Guadalupe, Zacatecas to Oaxtepec is 434 miles (699 km), about 7 h 23 min of driving without stops.

U.S. State Department travel advisory: Zacatecas — Level 4, Do Not Travel; Aguascalientes — Level 2, Exercise Increased Caution; Jalisco — Level 3, Reconsider Travel; Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased Caution; State of Mexico — Level 2, Exercise Increased Caution; Hidalgo — Level 2, Exercise Increased Caution; Mexico City — Level 2, Exercise Increased Caution; Morelos — Level 3, Reconsider TravelAdvisory issued May 29, 2026; checked September 29, 2026. Morelos is the Mexican state that contains Oaxtepec. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Museo de la InsurgenciaMuseo Espacio, AguascalientesCerro de las CampanasEl Cimatario National ParkTemplo y exconvento de San FranciscoSalón de la Plástica MexicanaMuseo Nacional de HistoriaTeatro de los InsurgentesMuseo Dolores OlmedoGuadalupe, ZacatecasOaxtepec
Route from Guadalupe, Zacatecas to Oaxtepec with the 9 stops listed below (blue dots).
Distance434 mi (699 km)
Driving time, no stops7 h 23 min
Main roads, in orderMEX-45D → MEX-45 → MEX-47D → MEX-57D → MEX-57 → Periférico → MEX-95D → MEX-160D
Mexican states on the routeZacatecas (Level 4), Aguascalientes (Level 2), Jalisco (Level 3), Guanajuato (Level 3), Querétaro (Level 2), State of Mexico (Level 2), Hidalgo (Level 2), Mexico City (Level 2), Morelos (Level 3)
Toll roadsMEX-45D, MEX-43D, MEX-47D, MEX-57D, MEX-95D, MEX-115D, MEX-160D
Fuel estimate (car at 25 mpg)about 17.4 gal; actual use varies by vehicle and traffic
Stops listed below9

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Guadalupe, Zacatecas to Oaxtepec is like

MEX-45D (163 mi) and MEX-57D (74 mi) carry about 55% of the 434 miles. MEX-45D, MEX-47D, MEX-57D, MEX-95D, MEX-160D are toll highways (cuota); MEX-45, MEX-57 are free federal roads (libre). It runs through 9 states: Zacatecas, Aguascalientes, Jalisco, Guanajuato, Querétaro, State of Mexico, Hidalgo, Mexico City, Morelos. Of the 9 stops listed below, 4 are within a mile of the road.

The route from Guadalupe, Zacatecas to Oaxtepec, road by road

RoadRoute miles (from–to)Length, miState
local roads0–44Zacatecas
MEX-45D4–2521Zacatecas
MEX-4525–5328Zacatecas, Aguascalientes
local roads53–574Aguascalientes
MEX-4557–8730Aguascalientes, Jalisco
MEX-45D87–229142Jalisco, Guanajuato
MEX-47D229–28152Guanajuato, Querétaro
MEX-57D281–35574Querétaro, State of Mexico, Hidalgo
MEX-57355–3638State of Mexico
connecting roads363–3641State of Mexico
Periférico364–38218State of Mexico, Mexico City
connecting roads382–3842Mexico City
MEX-95D384–41632Mexico City, Morelos
connecting roads416–4171Morelos
MEX-160D417–43215Morelos
local roads432–4342Morelos
  • Mile 30 of this route: Zacatecas → Aguascalientes (state line)
  • Mile 83 of this route: Aguascalientes → Jalisco (state line)
  • Mile 132 of this route: Jalisco → Guanajuato (state line)
  • Mile 241 of this route: Guanajuato → Querétaro (state line)
  • Mile 283 of this route: Querétaro → State of Mexico (state line)
  • Mile 316 of this route: State of Mexico → Hidalgo (state line)
  • Mile 336 of this route: Hidalgo → State of Mexico (state line)
  • Mile 368 of this route: State of Mexico → Mexico City (state line)
  • Mile 401 of this route: Mexico City → Morelos (state line)

Stops between Guadalupe, Zacatecas and Oaxtepec

  • Right off the route (under 1 mile): Museo Espacio, Aguascalientes (mile 67), Templo y exconvento de San Francisco (mile 329), Museo Nacional de Historia (mile 369), Teatro de los Insurgentes (mile 373)
  • Nature and outdoors: Cerro de las Campanas (mile 240), El Cimatario National Park (mile 245)
  • Museums and history: Museo de la Insurgencia (mile 48), Museo Espacio, Aguascalientes (mile 67), Salón de la Plástica Mexicana (mile 369), Museo Nacional de Historia (mile 369), Museo Dolores Olmedo (mile 386)

Museo de la Insurgencia

Mile 48 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Set in a 17th-century estate, the Museo de la Insurgencia opened in 1964 to tell the story of Mexico's independence movement. One hall shows farm, mining and textile tools from hacienda work; another displays everyday objects from past eras.

Museo Espacio, Aguascalientes

Mile 67 · Art museum · 0.8 mi from the route

Inside the Tres Centurias complex at Aguascalientes' old train station, Museo Espacio is a contemporary art museum, so a visit pairs current work with a look at the city's railroad buildings.

Cerro de las Campanas

Mile 240 · National Park of Mexico · 12 mi from the route · side trip; actual detour depends on access roads

Rising within Querétaro City, the Cerro de las Campanas is a hill that is protected as a Mexican national park.

El Cimatario National Park

Mile 245 · National Park of Mexico · 9 mi from the route · side trip; actual detour depends on access roads

El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.

Templo y exconvento de San Francisco

Mile 329 · Convent · 0.6 mi from the route

The Templo y Exconvento de San Francisco is a church and former convent located in the city of Tepeji del Río, in the Mexican state of Hidalgo.

Salón de la Plástica Mexicana

Mile 369 · Art museum · 2 mi from the route · side trip; actual detour depends on access roads

Established in 1949 to expand the market for Mexican art, the Salón de la Plástica Mexicana is an institution devoted to promoting contemporary Mexican art.

Museo Nacional de Historia

Mile 369 · National museum · 0.9 mi from the route

Inside Chapultepec Castle in Chapultepec Park, the National Museum of History (Museo Nacional de Historia) covers Mexico's past as one of the country's national museums.

Teatro de los Insurgentes

Mile 373 · Theatre building · 0.6 mi from the route

Opened in 1953, Teatro de los Insurgentes is a theater on Mexico City's Avenida de los Insurgentes, with seating for 959 spectators.

Museo Dolores Olmedo

Mile 386 · Art museum · 2 mi from the route · side trip; actual detour depends on access roads

In Xochimilco, the Museo Dolores Olmedo is an art museum built around the collection of Mexican businesswoman Dolores Olmedo.

When you get to Oaxtepec

Former convent of Saint Dominic de Guzmán

Convent · in Oaxtepec

In Oaxtepec, the Exconvento de Santo Domingo de Guzmán is among the first convents the Dominicans built in Mexico, and its walls preserve extensive fresco painting from the colonial era.

Templo y Exconvento de San Juan Bautista de Tlayacapan

Convent · in Oaxtepec

Augustinian friars began this fortress-like church and monastery in the 16th century. Part of the UNESCO-listed group of monasteries on the slopes of Popocatépetl, its former cloister now holds a museum with 17th-century murals and religious art.

More drives to Oaxtepec

From Guadalupe, Zacatecas to other places in Mexico

Frequently asked questions

How long is the drive from Guadalupe, Zacatecas to Oaxtepec?

About 7 h 23 min of driving without stops, over 434 miles.

How far is Oaxtepec from Guadalupe, Zacatecas by car?

About 434 miles (699 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Guadalupe, Zacatecas to Oaxtepec?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Guadalupe, Zacatecas to Oaxtepec?

The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Mexico City Level 2: Exercise Increased Caution; Morelos Level 3: Reconsider Travel (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Guadalupe, Zacatecas to Oaxtepec use?

In order: MEX-45D, MEX-45, MEX-47D, MEX-57D, MEX-57, Periférico, MEX-95D and MEX-160D. The road-by-road table above shows the route miles and states for each one.

What are good stops between Guadalupe, Zacatecas and Oaxtepec?

Closest to the road: Museo Espacio, Aguascalientes (art museum, mile 67, 0.8 mi from the route); Templo y exconvento de San Francisco (convent, mile 329, 0.6 mi from the route); Teatro de los Insurgentes (theatre building, mile 373, 0.6 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.