Guadalupe, Zacatecas, Mexico to San Blas is about 364 road miles (585 km): roughly 6 h 20 min at the wheel if you don't stop.
| Distance by road | 364 mi (585 km) |
|---|---|
| Drive time without stops | 6 h 20 min |
| Main roads, in order | MEX-45D → MEX-45 → MEX-80D → MEX-15D → MEX-15 → NAY 12 |
| Mexican states on the route | Zacatecas, Aguascalientes, Jalisco, Nayarit |
| Toll roads (as marked in OpenStreetMap) | MEX-45D, MEX-80D, MEX-90D, MEX-15D |
| Fuel estimate (car at 25 mpg) | about 14.5 gal; actual use varies by vehicle and traffic |
| Stops listed below | 7 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
How the Guadalupe, Zacatecas to San Blas drive plays out
MEX-15D (149 mi) and MEX-80D (87 mi) carry about 65% of the 364 miles. It runs through 4 states: Zacatecas, Aguascalientes, Jalisco, Nayarit. OpenStreetMap marks tolled sections on MEX-45D, MEX-80D and MEX-90D. Of the 7 stops listed below, 2 are within a mile of the road.
Guadalupe, Zacatecas to San Blas: the road sequence
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–4 | 4 | Zacatecas |
| MEX-45D | 4–25 | 21 | Zacatecas |
| MEX-45 | 25–53 | 28 | Zacatecas, Aguascalientes |
| local roads | 53–57 | 4 | Aguascalientes |
| MEX-45 | 57–87 | 30 | Aguascalientes, Jalisco |
| MEX-45D | 87–100 | 13 | Jalisco |
| local roads | 100–112 | 12 | Jalisco |
| MEX-80D | 112–199 | 87 | Jalisco |
| MEX-15D | 199–211 | 12 | Jalisco |
| MEX-15 | 211–219 | 8 | Jalisco |
| MEX-15D | 219–356 | 137 | Jalisco, Nayarit |
| NAY 12 | 356–361 | 5 | Nayarit |
| local roads | 361–364 | 3 | Nayarit |
- Mile 30 of this route: Zacatecas → Aguascalientes (state line)
- Mile 83 of this route: Aguascalientes → Jalisco (state line)
- Mile 268 of this route: Jalisco → Nayarit (state line)
Places worth a stop between Guadalupe, Zacatecas and San Blas
- Right off the route (under 1 mile): Museum of Contemporary Art (mile 68), Ixtlán del Rio (mile 278)
- Museums and history: Museum of Contemporary Art (mile 68), Cathedral Basilica of San Juan de los Lagos (mile 119), Basílica de San Felipe Neri (mile 204), Guachimontones (mile 233), Ixtlán del Rio (mile 278), Museo Regional de Nayarit (mile 330)
- With kids: Acuario Michin Guadalajara (mile 205)
Museum of Contemporary Art
Aguascalientes' Museum of Contemporary Art shows works by contemporary Mexican artists in its Jesús F. Contreras gallery.
Cathedral Basilica of San Juan de los Lagos
Gothic-style ribbed vaults rise over the interior of San Juan de los Lagos' cathedral basilica, built from 1732 to 1769, where you'll also find a silver-framed Way of the Cross.
Basílica de San Felipe Neri
Guadalajara's Basilica of San Felipe Neri is a Catholic church built in baroque style between 1752 and 1802 by master builder Pedro José Ciprés.
Acuario Michin Guadalajara
Acuario Michin Guadalajara is an aquarium in the city of Guadalajara, in the Mexican state of Jalisco.
Guachimontones
Near the town of Teuchitlán, Guachimontones is known for its circular structures. INAH describes it as the first large population center in western Mexico, emerging around 1000 BC, with two ball courts and about 40 circular buildings across 20 hectares.
Ixtlán del Rio
Between roughly 300 BC and AD 600, people made their home at Los Toriles in Ixtlán del Río. Today visitors come for its circular temple, a rare design in Mesoamerica.
Museo Regional de Nayarit
In the city of Tepic, the Museo Regional de Nayarit focuses on the different cultural traditions of pre-Hispanic Nayarit.
More drives to San Blas
- Guadalajara to San Blas
- Tepatitlán to San Blas
- San Juan de los Lagos to San Blas
- Zamora to San Blas
- Colima to San Blas
- Lagos de Moreno to San Blas
From Guadalupe, Zacatecas to other places in Mexico
- Guadalupe, Zacatecas to San Juan de los Lagos
- Guadalupe, Zacatecas to Temacapulín
- Guadalupe, Zacatecas to Tepatitlán
- Guadalupe, Zacatecas to Amatitán
- Guadalupe, Zacatecas to Ajijic
- Guadalupe, Zacatecas to Tequila
Continue Your Adventure
Frequently asked questions
How long does it take to drive from Guadalupe, Zacatecas, Mexico to San Blas?
About 6 h 20 min of driving without stops, over 364 miles.
What is the driving distance from Guadalupe, Zacatecas, Mexico to San Blas?
About 364 miles (585 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Guadalupe, Zacatecas to San Blas?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Guadalupe, Zacatecas to San Blas?
The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Nayarit Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
Which highways go from Guadalupe, Zacatecas to San Blas?
In order: MEX-45D, MEX-45, MEX-80D, MEX-15D, MEX-15 and NAY 12. The road-by-road table above shows the route miles for each one.
Where can you stop on the way from Guadalupe, Zacatecas to San Blas?
Closest to the road: Museum of Contemporary Art (art museum, mile 68, 0.2 mi from the route); Ixtlán del Rio (archaeological site, mile 278, 0.5 mi from the route); Museo Regional de Nayarit (museum, mile 330, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route: at least one strong stop for each stretch of the drive, then the best-known places nearest the road, up to nine in all. Places that are closed, private or not open to visitors are removed. Place descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.