Guadalupe, Zacatecas to Cadereyta Road Trip: Route & Stops

By admin, 3 October, 2026

The Wayro route from Guadalupe, Zacatecas to Cadereyta is 288 miles (464 km), about 5 h 21 min of driving without stops.

U.S. State Department travel advisory: Zacatecas — Level 4, Do Not Travel; Aguascalientes — Level 2, Exercise Increased Caution; Jalisco — Level 3, Reconsider Travel; Guanajuato — Level 3, Reconsider Travel; Querétaro — Level 2, Exercise Increased CautionAdvisory issued May 29, 2026; checked September 29, 2026. Querétaro is the Mexican state that contains Cadereyta. This route passes through a state at the advisory's highest level. Read the full advisory before you plan this drive.
Museo de la InsurgenciaMuseo EscarcegaHistoric centre of AguascalientesCelaya CathedralEl CerritoQuerétaro CathedralEl Cimatario National ParkGuadalupe, ZacatecasCadereyta
Route from Guadalupe, Zacatecas to Cadereyta with the 7 stops listed below (blue dots).
Distance288 mi (464 km)
Driving time, no stops5 h 21 min
Main roads, in orderMEX-45D → MEX-45 → MEX-57D → QRO 4 → QRO 5
Mexican states on the routeZacatecas (Level 4), Aguascalientes (Level 2), Jalisco (Level 3), Guanajuato (Level 3), Querétaro (Level 2)
Toll roadsMEX-45D, MEX-43D, MEX-57D
Fuel estimate (car at 25 mpg)about 11.5 gal; actual use varies by vehicle and traffic
Stops listed below7

Driving this route in a car with U.S. plates

Temporary vehicle import permit (TIP)Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora)
Mexican auto insuranceRequired for all vehicles: buy a Mexican policy before you drive

Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.

What the drive from Guadalupe, Zacatecas to Cadereyta is like

MEX-45D (180 mi) and MEX-45 (58 mi) carry about 83% of the 288 miles. MEX-45D, MEX-57D are toll highways (cuota); MEX-45 is a free federal road (libre). It runs through 5 states: Zacatecas, Aguascalientes, Jalisco, Guanajuato, Querétaro. Of the 7 stops listed below, 2 are within a mile of the road.

The route from Guadalupe, Zacatecas to Cadereyta, road by road

RoadRoute miles (from–to)Length, miState
local roads0–44Zacatecas
MEX-45D4–2521Zacatecas
MEX-4525–5328Zacatecas, Aguascalientes
local roads53–574Aguascalientes
MEX-4557–8730Aguascalientes, Jalisco
MEX-45D87–246159Jalisco, Guanajuato, Querétaro
MEX-57D246–25610Querétaro
connecting roads256–2571Querétaro
QRO 4257–27619Querétaro
QRO 5276–2804Querétaro
local roads280–2888Querétaro
  • Mile 30 of this route: Zacatecas → Aguascalientes (state line)
  • Mile 83 of this route: Aguascalientes → Jalisco (state line)
  • Mile 132 of this route: Jalisco → Guanajuato (state line)
  • Mile 238 of this route: Guanajuato → Querétaro (state line)

Stops between Guadalupe, Zacatecas and Cadereyta

  • Right off the route (under 1 mile): Museo Escarcega (mile 68), Historic centre of Aguascalientes (mile 68)
  • Nature and outdoors: El Cimatario National Park (mile 249)
  • Museums and history: Museo de la Insurgencia (mile 48), Museo Escarcega (mile 68), Historic centre of Aguascalientes (mile 68), Celaya Cathedral (mile 217), El Cerrito (mile 241), Querétaro Cathedral (mile 245)

Museo de la Insurgencia

Mile 48 · Museum · 3 mi from the route · side trip; actual detour depends on access roads

Set in a 17th-century estate, the Museo de la Insurgencia opened in 1964 to tell the story of Mexico's independence movement. One hall shows farm, mining and textile tools from hacienda work; another displays everyday objects from past eras.

Museo Escarcega

Mile 68 · Art museum · 0.6 mi from the route

Eduardo Escárcega Rangel created this museum in the city of Aguascalientes to show his personal collection of paintings and prints by local, national and international artists.

Historic centre of Aguascalientes

Mile 68 · Historic district · 0.2 mi from the route

The historic center of Aguascalientes is the city's zone of historic monuments, which INAH has declared part of the nation's heritage.

Celaya Cathedral

Mile 217 · Church building · 2 mi from the route · side trip; actual detour depends on access roads

Celaya's main Catholic church, the Immaculate Conception Cathedral, occupies the space of a former chapel that was annexed to the neighboring Temple of St. Francis.

El Cerrito

Mile 241 · Archaeological site · 2 mi from the route

Just outside Querétaro city in Corregidora, El Cerrito is an INAH archaeological zone centered on a pyramid close to 100 feet high, later topped by a 19th-century fort, with a small site museum on the grounds.

Querétaro Cathedral

Mile 245 · Catholic cathedral · 1 mi from the route

Querétaro's cathedral, dedicated to St. Philip Neri, is a Catholic church built by the Oratory of Saint Philip Neri in Santiago de Querétaro.

El Cimatario National Park

Mile 249 · National Park of Mexico · 3 mi from the route · side trip; actual detour depends on access roads

El Cimatario National Park protects about 24 square kilometers of land just south of the city of Santiago de Querétaro.

More drives to Cadereyta

From Guadalupe, Zacatecas to other places in Mexico

Frequently asked questions

How long is the drive from Guadalupe, Zacatecas to Cadereyta?

About 5 h 21 min of driving without stops, over 288 miles.

How far is Cadereyta from Guadalupe, Zacatecas by car?

About 288 miles (464 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.

Do I need a permit to drive my U.S. car from Guadalupe, Zacatecas to Cadereyta?

Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.

Is it safe to drive from Guadalupe, Zacatecas to Cadereyta?

The U.S. State Department rates Zacatecas Level 4: Do Not Travel; Aguascalientes Level 2: Exercise Increased Caution; Jalisco Level 3: Reconsider Travel; Guanajuato Level 3: Reconsider Travel; Querétaro Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.

What roads does the drive from Guadalupe, Zacatecas to Cadereyta use?

In order: MEX-45D, MEX-45, MEX-57D, QRO 4 and QRO 5. The road-by-road table above shows the route miles and states for each one.

What are good stops between Guadalupe, Zacatecas and Cadereyta?

Closest to the road: Historic centre of Aguascalientes (historic district, mile 68, 0.2 mi from the route); Museo Escarcega (art museum, mile 68, 0.6 mi from the route); Querétaro Cathedral (catholic cathedral, mile 245, 1 mi from the route). All stops are described above.

How we put this guide together

Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.

Route data © OpenStreetMap contributors.