The Wayro route from Guadalajara to Tlaxcala is 401 miles (646 km), about 6 h 18 min of driving without stops.
| Distance | 401 mi (646 km) |
|---|---|
| Driving time, no stops | 6 h 18 min |
| Main roads, in order | MEX-15D → MEX-M40D → MEX-117D |
| Mexican states on the route | Jalisco (Level 3), Michoacán (Level 4), State of Mexico (Level 2), Hidalgo (Level 2), Tlaxcala (Level 2), Puebla (Level 2) |
| Toll roads | MEX-15D, MEX-M40D, MEX-117D |
| Fuel estimate (car at 25 mpg) | about 16.1 gal; actual use varies by vehicle and traffic |
| Stops listed below | 8 |
Driving this route in a car with U.S. plates
| Temporary vehicle import permit (TIP) | Required: this route is outside the zones where U.S.-registered cars can skip the temporary import permit (Baja California, Baja California Sur and part of Sonora) |
|---|---|
| Mexican auto insurance | Required for all vehicles: buy a Mexican policy before you drive |
Sources: U.S. State Department, Mexico travel information (updated August 11, 2026); permits are issued by Banjercito.
What the drive from Guadalajara to Tlaxcala is like
MEX-15D (245 mi) and MEX-M40D (137 mi) carry about 95% of the 401 miles. MEX-15D, MEX-M40D, MEX-117D are toll highways (cuota). It runs through 6 states: Jalisco, Michoacán, State of Mexico, Hidalgo, Tlaxcala, Puebla. Of the 8 stops listed below, 1 are within a mile of the road.
The route from Guadalajara to Tlaxcala, road by road
| Road | Route miles (from–to) | Length, mi | State |
|---|---|---|---|
| local roads | 0–6 | 6 | Jalisco |
| MEX-15D | 6–251 | 245 | Jalisco, Michoacán, State of Mexico |
| MEX-M40D | 251–388 | 137 | State of Mexico, Hidalgo, Tlaxcala, Puebla |
| MEX-117D | 388–400 | 12 | Puebla, Tlaxcala |
| local roads | 400–401 | 1 | Tlaxcala |
- Mile 65 of this route: Jalisco → Michoacán (state line)
- Mile 233 of this route: Michoacán → State of Mexico (state line)
- Mile 283 of this route: State of Mexico → Hidalgo (state line)
- Mile 313 of this route: Hidalgo → State of Mexico (state line)
- Mile 327 of this route: State of Mexico → Hidalgo (state line)
- Mile 344 of this route: Hidalgo → State of Mexico (state line)
- Mile 356 of this route: State of Mexico → Hidalgo (state line)
- Mile 364 of this route: Hidalgo → Tlaxcala (state line)
- Mile 386 of this route: Tlaxcala → Puebla (state line)
- Mile 391 of this route: Puebla → Tlaxcala (state line)
Stops between Guadalajara and Tlaxcala
- Right off the route (under 1 mile): Tula National Park (mile 296)
- Nature and outdoors: Rayón National Park (mile 229), Tula National Park (mile 296)
- Museums and history: Teatro Morelos de Maravatío (mile 211), Museo Arqueológico de Apaxco (mile 312), Teotihuacan (mile 344)
Teatro Morelos de Maravatío
Maravatío's Teatro Morelos is a late-19th-century theater in a French-influenced neoclassical style, designed by architect Rafael Guerrero Torres. It opened on January 11, 1879, with a performance by opera singer Ángela Peralta.
Rayón National Park
Just outside Tlalpujahua, Rayón National Park (Parque Nacional Rayón) marks the start of the area's famous butterfly reserve country, which stretches south and west from here.
Atlantean figures
Crowning the main pyramid at the Tula archaeological zone, these basalt sculptures of Toltec warriors stand more than four meters tall in what was once the Toltec capital; the nearby Wall of Snakes shows carved serpents devouring skeletons.
Tula National Park
This park protects the ruins of Tula, ancient capital of the Toltecs. Walk up to the main pyramid to stand beside the Atlantes, basalt warrior figures more than four meters tall, and look for the Coatepantli wall's reliefs of snakes devouring skeletons.
Museo Arqueológico de Apaxco
Founded in 1985, the Museo Arqueológico de Apaxco sits across from the parish church of San Francisco de Asís and beside the town hall in Apaxco, State of Mexico.
Teotihuacan
Built between the 1st and 7th centuries AD, this UNESCO-listed ancient city lines the Avenue of the Dead, where you can walk between the Pyramid of the Sun, the Pyramid of the Moon and the Temple of the Feathered Serpent.
Aqueduct of Padre Tembleque
Built by Franciscan friar Francisco de Tembleque between 1554 and 1572, this 16th-century water system runs more than 48 km between Zempoala and Otumba. Its tallest arcade at Tepeyahualco reaches almost 40 meters, and UNESCO listed it in 2015.
Exconvent of Santa María Magdalena
The former convent of Santa María Magdalena (Exconvento de Santa María Magdalena) is a 17th-century Baroque church built by the Dieguino friars, still in use as a Catholic temple of the Archdiocese of Puebla.
When you get to Tlaxcala
Teatro Xicohténcatl
Tlaxcala's Teatro Xicohténcatl opened in 1873 and was reopened in 1888 after remodeling. Look up to see John Fulton's ceiling mural of the nine muses, painted in Art Nouveau style against a Tlaxcalan landscape.
Museo de Sitio de Ocotelulco
Ocotelulco was the principal Tlaxcalan lordship in 1519; its site museum displays about 750 excavated objects beside temple remains painted with Tezcatlipoca and the fire serpent, and an ethnobotanical garden surrounds the building.
Tlaxcala Cathedral
Part of a 16th-century Franciscan complex among the earliest in the Americas, Tlaxcala's cathedral is famous for its carved Mudéjar-style wooden ceiling. Look for the freestanding bell tower and the stone font where Tlaxcalan lords were baptized.
More drives to Tlaxcala
- Cuautla to Tlaxcala
- Toluca to Tlaxcala
- Cuernavaca to Tlaxcala
- San Juan del Río to Tlaxcala
- Zitácuaro to Tlaxcala
- San Miguel de Allende to Tlaxcala
From Guadalajara to other places in Mexico
- Guadalajara to Pabellón de Arteaga
- Guadalajara to Pabellón de Hidalgo
- Guadalajara to Calvillo
- Guadalajara to Real de Asientos
- Guadalajara to Guadalupe, Zacatecas
- Guadalajara to Zacatecas
Continue Your Adventure
Frequently asked questions
How long is the drive from Guadalajara to Tlaxcala?
About 6 h 18 min of driving without stops, over 401 miles.
How far is Tlaxcala from Guadalajara by car?
About 401 miles (646 km) on the Wayro route. Other map services may show a few miles more or less, depending on where they start and end in each city.
Do I need a permit to drive my U.S. car from Guadalajara to Tlaxcala?
Yes. A temporary vehicle import permit (TIP) is required for a U.S.-registered car on this route, which is outside the zones where it can be skipped. Mexican auto insurance is required for every vehicle.
Is it safe to drive from Guadalajara to Tlaxcala?
The U.S. State Department rates Jalisco Level 3: Reconsider Travel; Michoacán Level 4: Do Not Travel; State of Mexico Level 2: Exercise Increased Caution; Hidalgo Level 2: Exercise Increased Caution; Tlaxcala Level 2: Exercise Increased Caution; Puebla Level 2: Exercise Increased Caution (advisory issued May 29, 2026). Read the full advisory before you go.
What roads does the drive from Guadalajara to Tlaxcala use?
In order: MEX-15D, MEX-M40D and MEX-117D. The road-by-road table above shows the route miles and states for each one.
What are good stops between Guadalajara and Tlaxcala?
Closest to the road: Teatro Morelos de Maravatío (opera house, mile 211, 1 mi from the route); Tula National Park (National Park of Mexico, mile 296, 1 mi from the route); Atlantean figures (atlantean figures, mile 296, 1 mi from the route). All stops are described above.
How we put this guide together
Wayro calculates the route from OpenStreetMap road data; mile numbers are positions along this route, not highway mile markers, and "from the route" distances are straight-line, so the real detour depends on access roads. Stops are chosen from parks, natural sites, museums, historic sites and attractions close to the route (roughly 2 to 7 miles depending on the type, farther for World Heritage sites): at least one strong stop for each stretch of the drive, then the best-known places nearest the road, with no more than five of one type, up to nine in all. Places that are closed, private or not open to visitors are removed. Place and city descriptions are written by the Wayro team from official park, museum, tourism and government websites and other published sources. Safety levels and entry rules were checked against the U.S. Department of State on September 29, 2026. Conditions change, so check the linked sources before you travel.
Route data © OpenStreetMap contributors.